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List of works by Uffe Holmskov

A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine

scientific article

A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D.

scientific article published on February 2005

A simple two-step purification procedure for the iC3b binding collectin conglutinin

scientific article published on 9 September 2010

Activation of the respiratory burst by Pneumocystis carinii. Efficiency of different antibody isotypes, complement, lung surfactant protein D, and mannan-binding lectin.

scientific article published in March 2003

An enzyme-linked immunosorbent assay (ELISA) for quantification of mouse surfactant protein D (SP-D).

scientific article published on 29 November 2007

CD163-L1 is an endocytic macrophage protein strongly regulated by mediators in the inflammatory response

scientific article

CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site

scientific article

CL-46, a novel collectin highly expressed in bovine thymus and liver

scientific article published in November 2002

CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D

scientific article

Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis

scientific article

Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin

scientific article

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation

scientific journal article

Characterization of a novel human scavenger receptor cysteine-rich molecule SCART1 expressed by lymphocytes

scientific article

Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4.

scientific article

Chemotherapeutic treatment reduces circulating levels of surfactant protein-D in children with acute lymphoblastic leukemia

scientific article published on 26 September 2016

Circulating surfactant protein -D is low and correlates negatively with systemic inflammation in early, untreated rheumatoid arthritis

scientific article

Circulating surfactant protein D is associated to mortality in elderly women: a twin study

scientific article published on 20 August 2012

Cloning and characterization of SCART1, a novel scavenger receptor cysteine-rich type I transmembrane molecule

scientific article published on 17 March 2009

Collectin 11 (CL-11, CL-K1) is a MASP-1/3-associated plasma collectin with microbial-binding activity

scientific article published on 18 October 2010

Collections and ficolins: humoral lectins of the innate immune defense

scientific article

Complement Dependent and Independent Interaction Between Bovine Conglutinin and BCG: Implications in Bovine Tuberculosis

scholarly article by Arshad Mehmood et al published 2018 in Frontiers in Immunology

Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor

scientific article published on 17 December 2004

Critical role for cross-linking of trimeric lectin domains of surfactant protein D in antiviral activity against influenza A virus

scientific article

DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease.

scientific article published on 3 August 2007

DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands

scientific article

Detection of novel biomarkers of liver cirrhosis by proteomic analysis

scientific article

Distinctive anti-influenza properties of recombinant collectin 43.

scientific article

Dynamic strength of the interaction between lung surfactant protein D (SP-D) and saccharide ligands

scientific article

Elevated numbers of SCART1+ gammadelta T cells in skin inflammation and inflammatory bowel disease

scientific journal article

Enhancement of antiviral activity of collectin trimers through cross-linking and mutagenesis of the carbohydrate recognition domain

scientific article published on 24 December 2009

Enzyme-linked immunosorbent assay characterization of basal variation and heritability of systemic microfibrillar-associated protein 4.

scientific article

Evaluation of the biomarker candidate MFAP4 for non-invasive assessment of hepatic fibrosis in hepatitis C patients

scientific article published on 04 July 2016

Expression and localization of lung surfactant protein A in human tissues

scientific article (publication date: November 2003)

Expression and tissue localization of collectin placenta 1 (CL-P1, SRCL) in human tissues

scientific article

Expression of FIBCD1 by intestinal epithelial cells alleviates inflammation-driven tumorigenesis in a mouse model of colorectal cancer

scientific article published on 16 August 2023

FIBCD1 ameliorates weight loss in chemotherapy-induced murine mucositis

scientific article published on 12 September 2020

Ficolins and FIBCD1: soluble and membrane bound pattern recognition molecules with acetyl group selectivity

scientific article

Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer.

scientific article published on June 2003

Genetic influences on mannan-binding lectin (MBL) and mannan-binding lectin associated serine protease-2 (MASP-2) activity

scientific article published on January 2007

Genomic and molecular characterization of CL-43 and its proximal promoter

scientific article

Genomic and molecular characterization of bovine surfactant protein D (SP-D).

scientific article published in June 2004

Heritability estimates for the constitutional levels of the collectins mannan-binding lectin and lung surfactant protein D. A study of unselected like-sexed mono- and dizygotic twins at the age of 6-9 years.

scientific article published on July 2002

Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1

scientific journal article

Identification and characterization of a chitin-binding protein purified from coelomic fluid of the lugworm Arenicola marina defining a novel protein sequence family.

scientific article

Identification and characterization of porcine mannan-binding lectin A (pMBL-A), and determination of serum concentration heritability

scientific article published on 4 March 2006

Immunohistochemical Localization of Fibrinogen C Domain Containing 1 on Epithelial and Mucosal Surfaces in Human Tissues

scientific article

Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer.

scientific article

Induction of innate immunity by Aspergillus fumigatus cell wall polysaccharides is enhanced by the composite presentation of chitin and beta-glucan

scientific article published on 12 October 2013

Innate defense against influenza A virus: activity of human neutrophil defensins and interactions of defensins with surfactant protein D.

scientific article published in June 2006

Intestinal protozoan infections shape fecal bacterial microbiota in children from Guinea-Bissau

scientific article published on 03 March 2021

Ligand specificity of human surfactant protein D: expression of a mutant trimeric collectin that shows enhanced interactions with influenza A virus

scientific article

Lipid composition can predict mice native pulmonary surfactant membranes. 2. Fluid phase coexistence in bilayers and monolayers

article

Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions

scientific article

Long-term stability and circadian variation in circulating levels of surfactant protein D.

scientific article

Lung and salivary scavenger receptor glycoprotein-340 contribute to the host defense against influenza A viruses

scientific article

Lung surfactant protein D (SP-D) and the molecular diverted descendants: conglutinin, CL-43 and CL-46.

scientific article

M-ficolin is present in Aspergillus fumigatus infected lung and modulates epithelial cell immune responses elicited by fungal cell wall polysaccharides

scientific article published on 6 January 2017

MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation

scientific article published on 12 November 2015

MFAP4: a candidate biomarker for hepatic and pulmonary fibrosis?

Macrophage migration inhibitory factor (MIF) modulates trophic signaling through interaction with serine protease HTRA1.

scientific article

Microfibrillar-Associated Protein 4: A Potential Biomarker for Screening for Liver Fibrosis in a Mixed Patient Cohort

scientific article

Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma

scientific article published on 2 June 2015

Microfibrillar-associated protein 4: A potential biomarker of chronic obstructive pulmonary disease

scientific article (publication date: September 2014)

Native Pulmonary Surfactant Membranes in Mice Show Coexistence of Two Different Phases in Bilayers and Monolayers: When the Lipid Composition can Predict the Structural Phase Segregations

article

Native pulmonary surfactant membranes show similar phase segregation in bilayers and monolayers, both qualitatively and quantitatively, as predicted by lipid composition analysis

article

Novel characterisation of the gene encoding conglutinin reveals that previously characterised promoter corresponds to the CL-43 promoter

scientific article published on 01 September 2002

Novel expression of a functional trimeric fragment of human SP-A with efficacy in neutralisation of RSV.

scientific article

Plasma C3d levels of young farmers correlate with respirable dust exposure levels during normal work in swine confinement buildings.

scientific article published in January 2003

Plasma microfibrillar-associated protein 4 is not prognostic of emphysema progression but is associated with cardiovascular disease history and mortality in COPD patients

scholarly article by Sofie Lock Johansson et al published April 2019 in ERJ open research

Post-neonatal drop in alveolar SP-A expression: biological significance for increased vulnerability to SIDS?

scientific article published in February 2008

Protective effects of surfactant protein D treatment in 1,3-β-glucan-modulated allergic inflammation.

scientific article

Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D.

scientific article published on 5 February 2007

Respiratory innate immune proteins differentially modulate the neutrophil respiratory burst response to influenza A virus

scientific article published on 10 June 2005

Restoration of miR-330 expression suppresses lung cancer cell viability, proliferation, and migration

scientific article published on 24 June 2020

Review: Gp-340/DMBT1 in mucosal innate immunity

scientific article published on 23 April 2010

Salivary agglutinin and lung scavenger receptor cysteine-rich glycoprotein 340 have broad anti-influenza activities and interactions with surfactant protein D that vary according to donor source and sialylation

scientific article published on January 2006

Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas

scientific article published in October 2002

Serum surfactant protein D is correlated to development of dementia and augmented mortality.

scientific article published on 20 April 2007

Serum-surfactant SP-D correlates inversely to lung function in cystic fibrosis

scientific article published on 8 May 2010

Species differences in the carbohydrate binding preferences of surfactant protein D.

scientific article published on 02 March 2006

Surfactant protein D (SP-D) serum levels in patients with community-acquired pneumonia

scientific article published on 01 July 2003

Surfactant protein D binds to human immunodeficiency virus (HIV) envelope protein gp120 and inhibits HIV replication

scientific article

Surfactant protein D in newborn infants: factors influencing surfactant protein D levels in umbilical cord blood and capillary blood

scientific article published on 23 September 2005

Surfactant protein D is a candidate biomarker for subclinical tobacco smoke-induced lung damage

Surfactant protein D multimerization and gene polymorphism in COPD and asthma

scientific article

Surfactant protein D, a clinical biomarker for chronic obstructive pulmonary disease with excellent discriminant values

scientific article

Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia

scientific article

Surfactant protein-D-encoding gene variant polymorphisms are linked to respiratory outcome in premature infants

scientific article published on 9 July 2014

The SARS coronavirus spike glycoprotein is selectively recognized by lung surfactant protein D and activates macrophages

scientific article published on 26 January 2007

The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer

scientific article published in November 2002

The Scavenger Receptor Cysteine-Rich (SRCR) domain: an ancient and highly conserved protein module of the innate immune system

scientific article published on January 2004

The effects of GH and hormone replacement therapy on serum concentrations of mannan-binding lectin, surfactant protein D and vitamin D binding protein in Turner syndrome

scientific article published in March 2004

The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection

scientific article (publication date: 2012)

The presence and activity of SP-D in porcine coronary endothelial cells depend on Akt/PI3K, Erk and nitric oxide and decrease after multiple passaging

scientific article published on 17 November 2008

The recognition unit of FIBCD1 organizes into a noncovalently linked tetrameric structure and uses a hydrophobic funnel (S1) for acetyl group recognition

scientific article

Tissue localization of human trefoil factors 1, 2, and 3.

scientific article

Transit-amplifying ductular (oval) cells and their hepatocytic progeny are characterized by a novel and distinctive expression of delta-like protein/preadipocyte factor 1/fetal antigen 1.

scientific article published on April 2004

Viral aggregating and opsonizing activity in collectin trimers

scientific article

miR-142-3p as tumor suppressor miRNA in the regulation of tumorigenicity, invasion and migration of human breast cancer by targeting Bach-1 expression

scientific article published on 27 November 2018

miR-142-3p is a tumor suppressor that inhibits estrogen receptor expression in ER-positive breast cancer

scientific article published on 11 February 2019

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