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List of works by Jan Holmgren

5 year efficacy of a bivalent killed whole-cell oral cholera vaccine in Kolkata, India: a cluster-randomised, double-blind, placebo-controlled trial.

scientific article published on 18 October 2013

A Randomized, Controlled Trial of the Toxin-Blocking Effects of B Subunit in Family Members of Patients with Cholera ⬇️

scientific article published on 01 April 1984

A case for control of cholera in Africa by vaccination ⬇️

scientific article published on 04 September 2012

A double mutant heat-labile toxin from Escherichia coli, LT(R192G/L211A), is an effective mucosal adjuvant for vaccination against Helicobacter pylori infection

scientific article published on 25 February 2013

A novel non-antibiotic, lgt-based selection system for stable maintenance of expression vectors in Escherichia coli and Vibrio cholerae

scientific article

A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection

scientific article

A radial diffusion agar plaque technique for estimation of the avidity of bactericidal antibodies against Vibrio cholerae.

scientific article

A randomized, placebo-controlled trial of the bivalent killed, whole-cell, oral cholera vaccine in adults and children in a cholera endemic area in Kolkata, India

scientific article

A recombinant Escherichia coli heat-stable enterotoxin (STa) fusion protein eliciting anti-STa neutralizing antibodies

scientific article published on August 15, 1991

Absence of CD4+CD25+ regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice

scientific article published in June 2003

Actions of cholera toxin and the prevention and treatment of cholera

scientific article published on July 1981

Adoptive transfer of gut mucosal antitoxin memory by isolated B cells 1 year after oral immunization with cholera toxin.

scientific article

Alteration of the antibody response to Escherichia coli O antigen in mice by prior exposure to various somatic antigens

scientific article published on September 1975

Amplified ELISPOT assay for the detection of HIV-specific antibody-secreting cells in subhuman primates

scientific article published on August 30, 1992

An Antigenic Relationship Between Human Kidney, Colon and the Common Antigen of Enterobacteriaceae ⬇️

scientific article published on January 1, 1972

An agar plaque method for quantitation of vibriocidal antibodies

scientific article

An antigenic relationship between kidney and certain Escherichia coli strains

scientific article published on 01 January 1971

An oral B subunit-whole cell vaccine against cholera: from concept to successful field trial

scientific article published on 01 January 1987

An oral B subunit: whole cell vaccine against cholera

scientific article published on January 1, 1992

Analysis of expression of toxin-coregulated pili in classical and El Tor Vibrio cholerae O1 in vitro and in vivo ⬇️

scientific article published on October 1, 1992

Anatomic segmentation of the intestinal immune response in nonhuman primates: differential distribution of B cells after oral and rectal immunizations to sites defined by their source of vascularization

scientific article published on November 1999

Anti-bacterial and anti-toxic immunity induced by a killed whole-cell-cholera toxin B subunit cholera vaccine is essential for protection against lethal bacterial infection in mouse pulmonary cholera model

scientific article published on 28 November 2012

Antibodies and Antibody-Secreting Cells in the Female Genital Tract after Vaginal or Intranasal Immunization with Cholera Toxin B Subunit or Conjugates ⬇️

scientific article published on February 1, 1998

Antibodies in Human Serum and Milk Induced by Enterobacteria and Food Proteins ⬇️

scientific article published on April 26, 1977

Antibody responses in the lower respiratory tract and male urogenital tract in humans after nasal and oral vaccination with cholera toxin B subunit.

scientific article

Antibody-producing cells in peripheral blood and salivary glands after oral cholera vaccination of humans.

scientific article published on March 1991

Antigen-specific in vitro suppression of murine Helicobacter pylori-reactive immunopathological T cells by CD4CD25 regulatory T cells

scientific article published in July 2004

Antisense inhibition of delta-opioid receptor gene function in vivo by peptide nucleic acids.

scientific article published on April 2000

Antitoxic cholera immunity in mice: influence of antigen deposition on antitoxin-containing cells and protective immunity in different parts of the intestine

scientific article published on April 1980

Antitoxic immunity in experimental cholera: protection, and serum and local antibody responses in rabbits after enteral and parenteral immunization ⬇️

scientific article published on December 1, 1975

Asymptomatic bacteriuria--a serious disease? ⬇️

scientific article published on May 27, 1972

B Lymphocytes Treated In Vitro with Antigen Coupled to Cholera Toxin B Subunit Induce Antigen-Specific Foxp3+ Regulatory T Cells and Protect against Experimental Autoimmune Encephalomyelitis ⬇️

scientific article published on January 16, 2012

B-cell activation in duodenal mucosa after oral cholera vaccination in IgA deficient subjects with or without IgG subclass deficiency

scientific article published on 01 August 1993

Bacterial enteric infections and vaccine development

scientific article published on June 1, 1992

Binding of intraluminal toxin in cholera: trial of GM1 ganglioside charcoal ⬇️

scientific article published on October 25, 1980

Binding specificity of monoclonal antibodies to ganglioside, Fuc-GM1

scientific article published on 01 February 1986

Biodegradable polymeric microparticles for drug delivery and vaccine formulation: the surface attachment of hydrophilic species using the concept of poly(ethylene glycol) anchoring segments ⬇️

scientific article published on September 1, 1997

Boosting of Secretory IgA Antibody Responses in Man by Parenteral Cholera Vaccination ⬇️

scientific article published on January 1, 1977

Broad up-regulation of innate defense factors during acute cholera

scientific article published on 16 February 2007

CD4+CD25+ suppressor T cells regulate pathogen induced inflammation and disease

scientific article

COMMENTARY

scientific article (publication date: May 2007)

Cellular basis of immunomodulation by cholera toxin in vitro with possible association to the adjuvant function in vivo

scientific article published on 01 January 1989

Ceruloplasmin in patients with Duchenne muscular dystrophy

scientific article published on March 1, 1991

Changes in Intestinal Fluid Transport and Immune Responses to Enterotoxins Due to Concomitant Parasitic Infection ⬇️

scientific article published on December 1, 1980

Changes in intestinal fluid and mucosal immune responses to cholera toxin in Giardia muris infection and binding of cholera toxin to Giardia muris trophozoites

scientific article published on October 1985

Characterization of an internal permissive site in the cholera toxin B-subunit and insertion of epitopes from human immunodeficiency virus-1, hepatitis B virus and enterotoxigenic Escherichia coli

scientific article

Chemical and immunological characterisation of the major glucosamine-containing ganglioside of human tissues

scientific article published in August 1974

Chemical modification of cholera toxin for characterization of antigenic receptor-binding and toxic sites

scientific article published in August 1974

Chemical structure of carcinoma ganglioside antigens defined by monoclonal antibody C-50 and some allied gangliosides of human pancreatic adenocarcinoma

scientific article published on 01 March 1985

Chlorpromazine Reverses Diarrhea in Piglets Caused by Enterotoxigenic Escherichia coli ⬇️

scientific article published on June 1, 1979

Chlorpromazine inhibits cholera toxin-induced intestinal hypersecretion

scientific article published on June 1, 1977

Chlorpromazine reduces fluid-loss in cholera ⬇️

scientific article published on February 24, 1979

Cholera Toxin Induces a Transient Depletion of CD8+ Intraepithelial Lymphocytes in the Rat Small Intestine as Detected by Microarray and Immunohistochemistry.

scientific article published in November 2005

Cholera Toxin and the Adenylate Cyclase-Activating Signal ⬇️

scientific article published on March 1, 1976

Cholera Toxin, Ganglioside Receptors and the Immune Response ⬇️

scientific article published on January 1, 1976

Cholera and the immune response

scientific article published on January 1, 1983

Cholera antibody production in vitro by peripheral blood lymphocytes following oral immunization of humans and mice

scientific article published in October 1985

Cholera as a model for research on mucosal immunity and development of oral vaccines

scientific article published on August 1, 1992

Cholera due to altered El Tor strains of Vibrio cholerae O1 in Bangladesh

scientific article

Cholera toxin - a foe & a friend.

scientific article

Cholera toxin B subunit as a carrier molecule promotes antigen presentation and increases CD40 and CD86 expression on antigen-presenting cells

scientific article published on September 2001

Cholera toxin B subunit as transmucosal carrier-delivery and immunomodulating system for induction of antiinfectious and antipathological immunity

scientific article published on February 1996

Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance

scientific article published in November 1994

Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems

scientific article

Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 development

scientific article

Cholera toxin enhances alloantigen presentation by cultured intestinal epithelial cells

scientific article published on April 1993

Cholera toxin expression by El Tor Vibrio cholerae in shallow culture growth conditions

scientific article published on 14 November 2013

Cholera toxin induces a transient depletion of CD8+ intraepithelial lymphocytes in the rat small intestine as detected by microarray and immunohistochemistry

scientific article published on September 2005

Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro.

scientific article published on May 1991

Cholera toxin structure, gene regulation and pathophysiological and immunological aspects

scientific article

Cholera.

scientific article

Circulating cholera antitoxin memory cells in the blood one year after oral cholera vaccination in humans

scientific article published in August 1987

Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid protein

scientific article published on 7 January 2013

Cloning and sequencing of Vibrio cholerae mannose-sensitive haemagglutinin pilin gene: localization of mshA within a cluster of type 4 pilin genes

scientific article published on July 1994

Coexpression of ganglioside antigen Fuc-GM1, neural-cell adhesion molecule, carcinoembryonic antigen, and carbohydrate tumor-associated antigen CA 50 in lung cancer

scientific article published on 01 January 1992

Colorectal carcinomas have a characteristic ganglioside pattern

scientific article published on 01 February 1983

Comparison of different methods for serial dilution used in serological routine work

scientific article published on 01 January 1970

Comparison of receptors for cholera and Escherichia coli enterotoxins in human intestine.

scientific article

Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural cholera toxoid.

scientific article

Conformation of protein secreted across bacterial outer membranes: a study of enterotoxin translocation from Vibrio cholerae

scientific article

Construction and expression of immunogenic hybrid enterotoxigenic Escherichia coli CFA/I and CS2 colonization fimbriae for use in vaccines.

scientific article

Construction of a non-toxigenic Escherichia coli oral vaccine strain expressing large amounts of CS6 and inducing strong intestinal and serum anti-CS6 antibody responses in mice

scientific article published on 6 October 2011

Controlled trial of chlorpromazine as antisecretory agent in patients with cholera hydrated intravenously.

scientific article published on May 1982

Correlates of protection for enteric vaccines

scientific article published on 11 May 2017

Correlation between intestinal synthesis of specific immunoglobulin A and protection against experimental cholera in mice

scientific article

Cost of immunization with a locally produced, oral cholera vaccine in Viet Nam.

scientific article published on June 2001

Coupling of antigen to cholera toxin for dendritic cell vaccination promotes the induction of MHC class I-restricted cytotoxic T cells and the rejection of a cognate antigen-expressing model tumor

scientific article

CpG DNA as a potent inducer of mucosal immunity: implications for immunoprophylaxis and immunotherapy of mucosal infections

scientific article published on February 2004

CpG oligodeoxynucleotide augments HSV-2 glycoprotein D DNA vaccine efficacy to generate T helper 1 response and subsequent protection against primary genital herpes infection in mice

scientific article published on 17 October 2005

Cross-reactivity between heat labile enterotoxins of Vibrio cholerae and Escherichia coli in neutralization tests in rabbit ileum and skin ⬇️

scientific article published on 01 December 1973

Current status and future prospects for a vaccine against schistosomiasis

scientific article published on June 2004

Current status of an oral B subunit whole cell cholera vaccine

scientific article published in January 1983

Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin

scientific article published on 11 September 2017

Dendritic cell vaccination protects mice against lethality caused by genital herpes simplex virus type 2 infection

scientific article published in May 2001

Dendritic cell-mediated induction of mucosal cytotoxic responses following intravaginal immunization with the nontoxic B subunit of cholera toxin

scientific article published on March 2006

Detection by monoclonal antibody of carbohydrate antigen CA 50 in serum of patients with carcinoma

scientific article

Detection of a ganglioside antigen associated with small cell lung carcinomas using monoclonal antibodies directed against fucosyl-GM1.

scientific article

Detoxification of cholera toxin without removal of its immunoadjuvanticity by the addition of (STa-related) peptides to the catalytic subunit. A potential new strategy to generate immunostimulants for vaccination

scientific article published on 27 June 2002

Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administe

scientific article published on 27 March 2013

Development of improved cholera vaccine based on subunit toxoid ⬇️

scientific article published on October 13, 1977

Development of oral vaccines against cholera and enterotoxinogenic Escherichia coli diarrhea

scientific article published on January 1990

Development of oral vaccines against enterotoxinogenic Escherichia coli diarrhoea

scientific article

Development of pathogenicity-driven definitions of outcomes for a field trial of a killed oral vaccine against enterotoxigenic Escherichia coli in Egypt: application of an evidence-based method

scientific article published on 25 May 2004

Development of stable Vibrio cholerae O1 Hikojima type vaccine strains co-expressing the Inaba and Ogawa lipopolysaccharide antigens

scientific article

Diagnostic tests, treatment and follow-up in heart failure patients--is there a gender bias in the coherence to guidelines?

scientific article published in December 1999

Different secretory immunoglobulin A antibody responses to cholera vaccination in Swedish and Pakistani women.

scientific article

Differential Kinetics and Distribution of Antibodies in Serum and Nasal and Vaginal Secretions after Nasal and Oral Vaccination of Humans ⬇️

scientific article published on July 1, 1998

Differential effect of cholera toxin on CD45RA+ and CD45RO+ T cells: specific inhibition of cytokine production but not proliferation of human naive T cells

scientific article published in August 2000

Differential expression of intestinal membrane transporters in cholera patients

scientific article

Differential expression of tissue-specific adhesion molecules on human circulating antibody-forming cells after systemic, enteric, and nasal immunizations. A molecular basis for the compartmentalization of effector B cell responses

scientific article published on March 1997

Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice

scientific article published in April 2001

Distribution of lymphocytes and adhesion molecules in human cervix and vagina

article published in 1999

Duchenne muscular dystrophy. Effects of vitamin E administration on urinary luminescence

scientific article published on 01 October 1998

Effect of experimental trichinosis on intestinal secretion and on local antibody formation to cholera toxin

scientific article published on 01 January 1980

Effect of neutralization of gastric acid on immune responses to an oral B subunit, killed whole-cell cholera vaccine

scientific article published on 01 July 1986

Effect of pre-existing immunity for systemic and mucosal immune responses to intranasal immunization with group B Streptococcus type III capsular polysaccharide-cholera toxin B subunit conjugate

scientific article published on 01 May 2001

Effect of protein release rates from tablet formulations on the immune response after sublingual immunization ⬇️

scientific article published on August 29, 2012

Effects of oral vaccination and immunomodulation by cholera toxin on experimental Helicobacter pylori infection, reinfection, and gastritis

scientific article

Effects of undernutrition on infection with Vibrio cholerae O1 and on response to oral cholera vaccine.

scientific article

Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial

scientific article published on 8 October 2009

Efficacy of a low-cost, inactivated whole-cell oral cholera vaccine: results from 3 years of follow-up of a randomized, controlled trial

scientific article

Enhanced immunological tolerance against allograft rejection by oral administration of allogeneic antigen linked to cholera toxin B subunit

scientific article published on 01 November 2000

Enhancement of the IgG antibody production to Escherichia coli O antigen by prior exposure to serologically different E. coli bacteria

scientific article published on 01 January 1974

Enteric infections in an endemic area induce a circulating antibody-secreting cell response with homing potentials to both mucosal and systemic tissues

scientific article published in June 1998

Enteric vaccines for the developing world: a challenge for mucosal immunology

scientific article published on 6 May 2009

Enterotoxigenic Escherichia coli diarrhea in an endemic area prepares the intestine for an anamnestic immunoglobulin A antitoxin response to oral cholera B subunit vaccination.

scientific article published on January 1988

Enterotoxin antibodies in relation to diarrhoea in Swedish soldiers in Cyprus ⬇️

scientific article published on January 1, 1977

Enterotoxin-producing bacteria and parasites in stools of Ethiopian children with diarrhoeal disease ⬇️

scientific article published on November 1, 1976

Enterotoxin-specific immunoglobulin E responses in humans after infection or vaccination with diarrhea-causing enteropathogens

scientific article published on October 2000

Enzyme-linked immunosorbent assay for determination of antibodies to Vibrio cholerae toxin-coregulated pili

scientific article published on November 1, 1992

Enzyme-linked immunosorbent assays for cholera serology

scientific article

Epitope differences in toxin-coregulated pili produced by classical and El Tor Vibrio cholerae O1.

scientific article published in September 1991

European Commission COST/STD Initiative. Report of the expert panel VI. Concerted efforts in the field of mucosal immunology

scientific article published on May 1996

Evaluation of a ganglioside immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin ⬇️

scientific article published on December 1, 1979

Evidence for several waves of global transmission in the seventh cholera pandemic

scientific article

Experimental Studies on Cholera Immunisation: The Protective Immunogenicity in Rabbits of Monomeric and Polymeric Crude Exotoxin

scientific article published on August 1, 1973

Experimental studies on cholera immunization. 1. The response of neutralizing and vibriocidal antibodies in rabbits after immunization with culture filtrate material from V. cholerae

scientific article published on January 1, 1972

Experimental studies on cholera immunization. II. Evidence for protective antitoxic immunity mediated by serum antibodies as well as local antibodies.

scientific article

Exploration of mucosal immunity in humans: relevance to vaccine development

scientific article published in January 1994

Expression of cholera toxin under non-AKI conditions in Vibrio cholerae El Tor induced by increasing the exposed surface of cultures.

scientific article published on March 2004

Expression of the Escherichia coli lamB gene in Vibrio cholerae

scientific article published in June 1986

Extracellular secretion of STa heat-stable enterotoxin by Escherichia coli after fusion to a heterologous leader peptide

scientific article published on 01 September 1993

Field trial of inactivated oral cholera vaccines in Bangladesh: results from 5 years of follow-up

scientific article

Five-year immunologic memory in Swedish volunteers after oral cholera vaccination

scientific article published in February 1988

Fixation and inactivation of cholera toxin by GM1 ganglioside

scientific article published on 01 January 1973

Fracture strength of two oxide ceramic crown systems after cyclic pre-loading and thermocycling

scientific article published in September 2006

Fusion of genes encoding Escherichia coli heat-stable enterotoxin and outer membrane protein OmpC.

scientific article

Gamma-interferon-mediated down-regulation of electrolyte secretion by intestinal epithelial cells: a local immune mechanism?

scientific article

Gangliosides as receptors for bacterial toxins and Sendai virus.

scientific article published in January 1980

Genetic fusion of a non-toxic heat-stable enterotoxin-related decapeptide antigen to cholera toxin B-subunit

scientific article published on December 1988

Genetic fusion of human insulin B-chain to the B-subunit of cholera toxin enhances in vitro antigen presentation and induction of bystander suppression in vivo.

scientific article

Genital antibody responses in mice after intranasal infection with an attenuated candidate vector strain of Bordetella pertussis

scientific article

Group B Streptococcus capsular polysaccharide-cholera toxin B subunit conjugate vaccines prepared by different methods for intranasal immunization

scientific article

Gut mucosal, salivary and serum antitoxic and antibacterial antibody responses in Swedes after oral immunization with B subunit-whole cell cholera vaccine

scientific article published on 01 January 1984

Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis

scientific article

High frequency of spontaneous interferon-gamma-producing cells in human tonsils: role of local accessory cells and soluble factors

scientific article published on 01 January 1993

Identification of a mannose-binding pilus on Vibrio cholerae El Tor.

scientific article published in December 1991

IgA isotype restriction in the mucosal but not in the extramucosal immune response after oral immunizations with cholera toxin or cholera B subunit

scientific article published on 01 January 1983

IgG and IgA Subclass Distribution of Antitoxin Antibody Responses after Oral Cholera Vaccination or Cholera Disease ⬇️

scientific article published on 01 January 1988

Immune mechanisms and protective antigens of Vibrio cholerae serogroup O139 as a basis for vaccine development

scientific article published on September 1996

Immunizations of monkeys with synthetic peptides disclose conserved areas on gp120 of human immunodeficiency virus type 1 associated with cross-neutralizing antibodies and T-cell recognition

scientific article published on December 1991

Immunoactive chimeric ST-LT enterotoxins of Escherichia coli generated by in vitro gene fusion.

scientific article

Immunoassays based on plastic-adsorbed gangliosides

scientific article published on 01 January 1980

Immunochemical Studies of Two Cholera Toxin-Containing Standard Culture Filtrate Preparations of Vibrio cholerae.

scientific article

Immunodiffusion studies of pneumococcal antigens with special reference to serotype 27.

scientific article published in June 1973

Immunodiffusion studies on Escherichia coli. 1. Identification of O, K and H antigens in an O6 strain

scientific article

Immunodiffusion studies on Escherichia coli. 2. Characterization of antigens used for passive haemagglutination with an O 6 strain as model

scientific article published in January 1969

Immunodiffusion studies on pneumococcal antigens with special reference to serotype 27.

scientific article

Immunoglobulin and specific-antibody synthesis in vitro by enteral and nonenteral lymphoid tissues after subcutaneous cholera immunization

scientific article

Immunohistochemical detection of two small cell lung carcinoma-associated antigens defined by MAbs F12 and 123C3 in bronchoscopy biopsy tissues ⬇️

scientific article published on 01 September 1991

Immunohistological detection of fucosyl-GM1 ganglioside in human lung cancer and normal tissues with monoclonal antibodies

scientific article published in March 1989

Immunological Cross-Reactivity Between Human Kidney and Certain <i>E. coli</i> and Streptococcal Strains ⬇️

scientific article published on 01 January 1972

Immunological aspects of urinary tract infections

scientific article published on January 1, 1975

Immunological characterization of a rotavirus-neutralizing epitope fused to the cholera toxin B subunit

scientific article

Immunological memory after immunization with oral cholera B subunit--whole-cell vaccine in Swedish volunteers

scientific article published in September 1994

Impaired IFN-γ production after stimulation with bacterial components by natural killer cells from gastric cancer patients

article

Impaired mucosal antibody response to cholera toxin in vitamin A-deficient rats immunized with oral cholera vaccine.

scientific article published on September 1993

Impaired mucosal immune response in vitamin A deficient rats immunized with oral cholera vaccine

scientific article published on 01 January 1995

Important role for FcγRIIB on B lymphocytes for mucosal antigen-induced tolerance and Foxp3+ regulatory T cells

scientific article published on 13 September 2013

In vivo modulation of intracellular cAMP and cell growth of a lymphatic tumour in mice by cholera toxin ⬇️

scientific article published on August 1, 1977

In vivo suppression of allograft rejection by cyclic AMP increasing agents

scientific article published on January 1979

Induction and assessment of immunity at enteromucosal surfaces in humans: implications for vaccine development

scientific article

Induction and expression of intestinal humoral immunity in HIV-infected individuals: prospects for vaccination against secondary enteric infections

scientific article published on 01 January 1998

Induction of compartmentalized B-cell responses in human tonsils

scientific article

Induction of protective immunity by vaccination against Chlamydia trachomatis using the major outer membrane protein adjuvanted with CpG oligodeoxynucleotide coupled to the nontoxic B subunit of cholera toxin

scientific article published on 15 August 2009

Infection of vaginal and colonic epithelial cells by the human immunodeficiency virus type 1 is neutralized by antibodies raised against conserved epitopes in the envelope glycoprotein gp120.

scientific article

Insertion of a HIV-1-neutralizing epitope in a surface-exposed internal region of the cholera toxin B-subunit ⬇️

scientific article published on November 18, 1994

Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin

scientific article published on 01 March 2001

Interaction of cholera toxin and membrane GM1 ganglioside of small intestine ⬇️

scientific article published on July 1, 1975

Interaction of cholera toxin and toxin derivatives with lymphocytes. I. Binding properties and interference with lectin-induced cellular stimulation

scientific article

Interaction of cholera toxin and toxin derivatives with lymphocytes. II. Modulating effects of cholera toxin on in vivo humoral and cellular immune responses

scientific article published on January 1, 1976

Interaction of cholera toxin and toxin derivatives with lymphocytes. III. Modulating effects in vivo by cholera toxin on the graft-versus-host reactivity of lymphoid cells: suggested inhibition of suppressor cells

scientific article published on January 1, 1978

Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity

scientific article

Intestinal and circulating antibody-forming cells in IgA-deficient individuals after oral cholera vaccination

scientific article published on 01 February 1994

Intestinal and systemic immune responses in humans after oral immunization with a bivalent B subunit-O1/O139 whole cell cholera vaccine

scientific article published in October 1996

Intestinal antibody response after oral immunization with a prototype cholera B subunit-colonization factor antigen enterotoxigenic Escherichia coli vaccine

scientific article published in 1993

Intestinal antibody responses to oral vaccination in HIV-infected individuals

scientific article published on 01 August 1993

Intestinal immune response to cholera toxin: dependence on route and dosage of antigen for priming and boosting

scientific article

Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memory

scientific article

Intestinal immunoglobulin production after oral cholera vaccination in patients with IgA deficiency with or without IgG subclass deficiency

scientific article published on 01 January 1993

Intestinal mucosal memory and presence of memory cells in lamina propria and Peyer's patches in mice 2 years after oral immunization with cholera toxin

scientific article published in May 1986

Intranasal immunization of mice with group B streptococcal protein rib and cholera toxin B subunit confers protection against lethal infection

scientific article published on February 2004

Investigations into the safety and immunogenicity of a killed oral cholera vaccine developed in Viet Nam.

scientific article published on January 2002

Lack of Fc Gamma Receptor IIIA Promotes Rather than Suppresses Humoral and Cellular Immune Responses after Mucosal or Parenteral Immunization with Antigen and Adjuvants

scientific article published on 27 January 2017

Large-scale production of Vibrio cholerae toxin B subunit for use in oral vaccines

scientific article published on 01 December 1993

Local and systemic antibody responses and immunological memory in humans after immunization with cholera B subunit by different routes.

scientific article published on January 1984

Local and systemic antibody responses to naturally acquired enterotoxigenic Escherichia coli diarrhea in an endemic area

scientific article published on 01 March 1986

Local and systemic immune responses to rectal administration of recombinant cholera toxin B subunit in humans

scientific article

Local antibody production in experimental pyelonephritis: amount, avidity, and immunoglobulin class.

scientific article

Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours of an oral challenge immunization

scientific article published on 01 April 1987

Maternal cholera immunisation and scecretory IgA in breast milk

scientific article published on 01 April 1980

Mechanism of action of cholera toxin. Specific inhibition of toxin-induced activation of adenylate cyclase

scientific article published on July 15, 1975

Mechanism of toxin secretion by Vibrio cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins of Escherichia coli

scientific article published on December 1984

Mechanisms of Disease and Immunity in Cholera: A Review ⬇️

scientific article published on August 1, 1977

Migration routes and strategies in a highly aerial migrant, the common swift Apus apus, revealed by light-level geolocators

scientific article published in 2012

Monoclonal antibodies against Escherichia coli heat-stable toxin (STa) and their use in a diagnostic ST ganglioside GM1-enzyme-linked immunosorbent assay

scientific article published on October 1986

Monoclonal antibodies against gastrointestinal tumour-associated antigens isolated as monosialogangliosides

scientific article published on 01 January 1983

Monoclonal antibodies raised against NeuAc alpha 2-6neolactotetraosylceramide detect carcinoma-associated gangliosides

scientific article published in July 1985

Monoclonal antibodies to Escherichia coli heat-labile enterotoxins: neutralising activity and differentiation of human and porcine LTs and cholera toxin

scientific article published on 01 January 1986

Monoclonal antibodies to cholera toxin with special reference to cross-reactions with Escherichia coli heat-labile enterotoxin

scientific article published on May 1983

Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA.

scientific article

Mucosal and systemic antibody responses after peroral or intranasal immunization: effects of conjugation to enterotoxin B subunits and/or of co-administration with free toxin as adjuvant

scientific article published on 01 March 2000

Mucosal antitoxic and antibacterial immunity after cholera disease and after immunization with a combined B subunit-whole cell vaccine

scientific article published in June 1984

Mucosal delivery routes for optimal immunization: targeting immunity to the right tissues

scientific article published on January 2012

Mucosal immune response to cholera toxin--cellular basis of memory and adjuvant action

scientific article published in January 1988

Mucosal immunisation and adjuvants: a brief overview of recent advances and challenges

scientific article

Mucosal immunity and tolerance: relevance to vaccine development

scientific article

Mucosal immunity and vaccination.

scientific article published on December 1991

Mucosal immunity and vaccines

scientific article

Mucosal immunity: implications for vaccine development

scientific article

Mucosal vaccination increases local chemokine production attracting immune cells to the stomach mucosa of Helicobacter pylori infected mice ⬇️

scientific article published on 09 January 2012

Mucosal vaccines based on the use of cholera toxin B subunit as immunogen and antigen carrier

scientific article published in January 1994

Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit

scientific article published on January 2010

Multiple Attacks of Hepatitis in Drug Addicts: Biochemical, Immunochemical, and Morphologic Characteristics ⬇️

scientific article published on May 1, 1973

Nasal Administration of Schistosoma mansoni Egg Antigen-Cholera B Subunit Conjugate Suppresses Hepatic Granuloma Formation and Reduces Mortality in S. mansoni-Infected Mice

scientific article published on 01 November 2001

Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans

scientific article

Natural evolution and human consciousness

scientific article published on January 2014

Natural killer cells and Helicobacter pylori infection: bacterial antigens and interleukin-12 act synergistically to induce gamma interferon production

scientific article published on March 2005

Neutralizing antibodies against Escherichia coli and Vibrio cholerae enterotoxins in human milk from a developing country

scientific article published on 01 January 1976

New cholera vaccines

scientific article published in April 1989

New vaccines against bacterial enteric infections

scientific article published on January 1990

New-generation vaccines against cholera

scientific article

Non-O1 Vibrio cholerae in Thailand: homology with cloned cholera toxin genes.

scientific article published on February 1985

Nonimmunoglobulin fraction of human milk inhibits bacterial adhesion (hemagglutination) and enterotoxin binding of Escherichia coli and Vibrio cholerae.

scientific article

Novel carbohydrate binding site recognizing blood group A and B determinants in a hybrid of cholera toxin and Escherichia coli heat-labile enterotoxin B-subunits

scientific article published on 01 February 2000

Oligomeric structure of cholera toxin: characteristics of the H and L subunits

scientific article published on 01 January 1975

Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues

scientific article

Oral administration of cholera toxin B subunit conjugated to myelin basic protein protects against experimental autoimmune encephalomyelitis by inducing transforming growth factor-beta-secreting cells and suppressing chemokine expression

scientific article published on 01 October 2000

Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells

scientific article published on 01 November 1999

Oral immunization against cholera

scientific article published on January 1989

Oral tolerance induction with antigen conjugated to cholera toxin B subunit generates both Foxp3+CD25+ and Foxp3-CD25- CD4+ regulatory T cells

scientific article published on 01 December 2006

Oral tolerization with peptide 336-351 linked to cholera toxin B subunit in preventing relapses of uveitis in Behcet's disease

scientific article published in July 2004

Orally Administered CpG Oligodeoxynucleotide Induces Production of CXC and CC Chemokines in the Gastric Mucosa and Suppresses Bacterial Colonization in a Mouse Model of Helicobacter pylori Infection.

scientific article

Orally administered CpG oligodeoxynucleotide induces production of CXC and CC chemokines in the gastric mucosa and suppresses bacterial colonization in a mouse model of Helicobacter pylori infection

scientific article

Over-expression of major colonization factors of enterotoxigenic Escherichia coli, alone or together, on non-toxigenic E. coli bacteria.

scientific article

Phage display for site-specific immunization and characterization of high-risk human papillomavirus specific E7 monoclonal antibodies

scientific article

Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers

scientific article

Polystyrene-adsorbed gangliosides for investigation of the structure of the tetanus-toxin receptor

scientific article published on 01 May 1980

Precipitating antibodies to E. coli O antigens: a suggested difference in the antibody response of infants and children with first and recurrent attacks of pyelonephritis ⬇️

scientific article published in September 1969

Predisposition for cholera of individuals with O blood group. Possible evolutionary significance

scientific article

Preparation and preclinical evaluation of a freeze-dried formulation of a novel combined multivalent whole-cell/B-subunit oral vaccine against enterotoxigenic Escherichia coli diarrhea

scientific article published on 30 July 2016

Preparation and preclinical evaluation of experimental group B streptococcus type III polysaccharide-cholera toxin B subunit conjugate vaccine for intranasal immunization

scientific article

Prevention of mucosally induced uveitis with a HSP60-derived peptide linked to cholera toxin B subunit

scientific article published on 01 January 2003

Prolonged oral treatment with low doses of allergen conjugated to cholera toxin B subunit suppresses immunoglobulin E antibody responses in sensitized mice

scientific article published on 01 July 2000

Protection against Vibrio cholerae El Tor infection by specific antibodies against mannose-binding hemagglutinin pili ⬇️

scientific article published on November 1, 1992

Protection against cholera in breast-fed children by antibodies in breast milk.

scientific article

Protection against cholera toxin after oral immunization is thymus-dependent and associated with intestinal production of neutralizing IgA antitoxin

scientific article published on 01 April 1987

Protection against experimental Helicobacter pylori infection after immunization with inactivated H. pylori whole-cell vaccines

scientific article

Protective Capacity of Antibodies Against <i>E. coli</i>·Antigen with Special Reference to the Avidity ⬇️

scientific article published on 01 January 1974

Protective antitoxic cholera immunity in mice: influence of route and number of immunizations and mode of action of protective antibodies

scientific article published on August 1, 1978

Protective efficacy in humans of killed whole-vibrio oral cholera vaccine with and without the B subunit of cholera toxin

scientific article published on May 1987

Protective vaccination against genital herpes simplex virus type 2 (HSV-2) infection in mice is associated with a rapid induction of local IFN-gamma-dependent RANTES production following a vaginal viral challenge

scientific article published in December 2001

Protein Reagent Modification of Cholera Toxin: Characterization of Effects on Antigenic, Receptor-binding and Toxic Properties ⬇️

scientific article published on December 1, 1975

Proteomic analysis of cholera toxin adjuvant-stimulated human monocytes identifies Thrombospondin-1 and Integrin-β1 as strongly upregulated molecules involved in adjuvant activity

Public health. The cholera crisis in Africa

scientific article published in May 2009

Purification of El Tor cholera enterotoxins and comparisons with classical toxin

scientific article published on 01 September 1990

Purification of Vibrio cholerae soluble hemagglutinin and development of enzyme-linked immunosorbent assays for antigen and antibody quantitations ⬇️

scientific article published on July 1, 1983

Quantitation of Escherichia coli O antibodies by direct and indirect agglutination in comparison with a radioimmunoassay

scientific article published on 01 January 1975

Quantitation of vibriocidal antibodies using agar plague techniques

scientific article published on January 1, 1971

Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin.

scientific article

Recent advances in mucosal vaccines and adjuvants

scientific article

Recent developments in mucosal immunomodulatory adjuvants

scientific article

Receptor blocking, cholera, and Escherichia coli toxins

scientific article published on 01 November 1988

Receptor-Specific Large-Scale Purification of Cholera Toxin on Silica Beads Derivatized with LysoGM1 Ganglioside ⬇️

scientific article published on January 1, 1981

Receptor-like glycocompounds in human milk that inhibit classical and El Tor Vibrio cholerae cell adherence (hemagglutination) ⬇️

scientific article published on January 1, 1983

Receptors for cholera toxin and Escherichia coli heat-labile enterotoxin revisited.

scientific article published on January 1994

Recombinant cholera toxin B subunit and gene fusion proteins for oral vaccination.

scientific article

Recombinant fusion protein for simple detection of Escherichia coli heat-stable enterotoxin by GM1 enzyme-linked immunosorbent assay

scientific article published on October 1990

Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development

scientific article

Regulation of mammalian ornithine decarboxylase

scientific article

Relative significance of mannose-sensitive hemagglutinin and toxin-coregulated pili in colonization of infant mice by Vibrio cholerae El Tor.

scientific article published on August 1996

Reply on new drugs against type 2 diabetes: important to gain experience and knowledge

scientific article published in April 2008

Requirement for Cyclic AMP/Protein Kinase A-Dependent Canonical NFκB Signaling in the Adjuvant Action of Cholera Toxin and Its Non-toxic Derivative mmCT

article

Retrospective Analysis of Serotype Switching of Vibrio cholerae O1 in a Cholera Endemic Region Shows It Is a Non-random Process

scientific article

Reversal of cyclic AMP-mediated intestinal secretion in mice by chlorpromazine ⬇️

scientific article published on December 1, 1978

Robust gut associated vaccine-specific antibody-secreting cell responses are detected at the mucosal surface of Bangladeshi subjects after immunization with an oral killed bivalent V. cholerae O1/O139 whole cell cholera vaccine: comparison with other

article

Role of PCF8775 antigen and its coli surface subcomponents for colonization, disease, and protective immunogenicity of enterotoxigenic Escherichia coli in rabbits

scientific article published on February 1988

Role of antibodies against biotype-specific Vibrio cholerae pili in protection against experimental classical and El Tor cholera

scientific article

Role of local IgA antitoxin-producing cells for intestinal protection against cholera toxin challenge

scientific article published on 01 January 1989

Roles of different coli surface antigens of colonization factor antigen II in colonization by and protective immunogenicity of enterotoxigenic Escherichia coli in rabbits

scientific article published on February 1990

Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults.

scientific article

Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study

scientific article published on 5 November 2014

Safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli vaccine

scientific article published in January 1998

Safety and immunogenicity of an oral recombinant cholera B subunit-whole cell vaccine in Swedish volunteers

scientific article published on January 1, 1992

Saliva, breast milk, and serum antibody responses as indirect measures of intestinal immunity after oral cholera vaccination or natural disease

scientific article published on August 1986

Sendai virus receptor: proposed recognition structure based on binding to plastic-adsorbed gangliosides ⬇️

scientific article published on April 1, 1980

Sensitization and development of tolerance via the gut.

scientific article

Seroepidemiological studies of El Tor cholera in Bangladesh: association of serum antibody levels with protection

scientific article published in 1985

Serologic Differentiation Between Antitoxin Responses to Infection with Vibrio cholerae and Enterotoxin-Producing Escherichia coli ⬇️

scientific article published on March 1, 1983

Serum levels of the carcinoma-associated antigen CA 50 in ulcerative colitis.

scientific article

Sialosyllactotetraosylceramide, a novel ganglioside antigen detected in human carcinomas by a monoclonal antibody

scientific article published on 01 March 1985

Significance of amount and avidity of E. coli O antibodies for manifestation of their serological and protective properties. A preliminary study

scientific article published in January 1972

Specific-antibody-secreting cells in the rectums and genital tracts of nonhuman primates following vaccination

scientific article

Stool cyclic AMP in diarrhoea due to different causative organisms.

scientific article

Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier, and adjuvant.

scientific article

Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens

scientific article published on October 1986

Strong biotype and serotype cross-protective antibacterial and antitoxic immunity in rabbits after cholera infection

scientific article published on 01 August 1986

Structural basis for differential receptor binding of cholera and Escherichia coli heat-labile toxins: influence of heterologous amino acid substitutions in the cholera B-subunit.

scientific article

Structural studies of the Vibrio cholerae O-antigen ⬇️

scientific article published on January 1, 1979

Structure and arrangement of the cholera toxin genes in Vibrio cholerae O139.

scientific article published in April 1994

Studies of antibodies and immunoglobulin levels in urine from children with urinary tract infections caused by E. coli

scientific article published on 01 January 1970

Studies of methods for quantitation of agglutinins and precipitins to Escherichia coli O and K antigens

scientific article

Studies on protective effect of O and K antibodies against E. coli bacteria with regard to the immunoglobulin class.

scientific article published in January 1971

Sublingual 'oral tolerance' induction with antigen conjugated to cholera toxin B subunit generates regulatory T cells that induce apoptosis and depletion of effector T cells

scientific article published in August 2007

Sublingual immunization protects against Helicobacter pylori infection and induces T and B cell responses in the stomach

scientific article

Sublingual immunization with nonreplicating antigens induces antibody-forming cells and cytotoxic T cells in the female genital tract mucosa and protects against genital papillomavirus infection

scientific article published in December 2009

Sublingual vaccination ⬇️

scientific article published on January 1, 2011

Subunit structure of cholera toxin

scientific article published on 01 June 1973

Suppression of HIV replication in vitro by CpG and CpG conjugated to the non toxic B subunit of cholera toxin

scientific article published in May 2008

Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy

scientific article published on 01 October 1999

Surface expression of Helicobacter pylori HpaA adhesion antigen on Vibrio cholerae, enhanced by co-expressed enterotoxigenic Escherichia coli fimbrial antigens

scientific article published on 16 February 2017

Swedish Agency for Research Cooperation with Developing Countries. Prospects for public health benefits in developing countries from new vaccines against enteric infections

scientific article published in March 1991

Synergistic protective effect in rabbits of immunization with Vibrio cholerae lipopolysaccharide and toxin/toxoid ⬇️

scientific article published on March 1, 1976

Synthesis in Vibrio cholerae and secretion of hepatitis B virus antigens fused to Escherichia coli heat-labile enterotoxin subunit B.

scientific article

Synthesis of a precursor to the B subunit of heat-labile enterotoxin in Escherichia coli ⬇️

scientific article published on April 1, 1981

Synthesis of hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits: potential for use in a broad-spectrum vaccine

scientific article

Systemic and mucosal immune responses in mice after mucosal immunization with group B streptococcus type III capsular polysaccharide-cholera toxin B subunit conjugate vaccine

scientific article

Ten years of the Global Alliance for Vaccines and Immunization: challenges and progress

article

The Protective Effect against E. coli of O and K Antibodies of Different Immunoglobulin Classes ⬇️

scientific article published on 01 January 1972

The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity

scientific article published on 01 September 1992

The antibody response of children with pyelonephritis to different antigens of E. coli

scientific article published in January 1968

The bactericidal effect of normal human serum on E. coli strains from normals and from patients with urinary tract infections

scientific article

The binding of colonization factor antigens of enterotoxigenic Escherichia coli to intestinal cell membrane proteins

scientific article published on January 1990

The design and analysis of cholera vaccine trials: recent lessons from Bangladesh

scientific article

The isolation of an oxidase negative strain of Pseudomonas aeruginosa from the urine of a cobalt irradiated patient.

scientific article

The maltose regulon of Vibrio cholerae affects production and secretion of virulence factors.

scientific article published on November 1994

The primary and secondary antibody response to Escherichia coli O6 lipopolysaccharide analysed at the humoral and cellular level. Amount and avidity of the antibodies in relation to protective capacity ⬇️

scientific article published on February 1, 1973

The subcellular location of antigen expressed by adenoviral vectors modifies adaptive immunity but not dependency on cross-presenting dendritic cells

scientific article published on 6 July 2011

The use of chlorpromazine in the treatment of cholera and other severe acute watery diarrheal diseases

scientific article published on 01 June 1982

The validity of the ammonium sulphate precipitation technique of estimation of antibody amount and avidity ⬇️

scientific article published on December 1, 1973

Thermostability of the coating, antigen and immunostimulator in an adjuvanted oral capsule vaccine formulation

scientific article published on 9 October 2017

Tissue receptor for cholera exotoxin: postulated structure from studies with GM1 ganglioside and related glycolipids.

scientific article

Tissue receptor for cholera exotoxin: structural requirements of G11 ganglioside in toxin binding and inactivation.

scientific article

Topical immunization strategies

scientific article published on 22 September 2010

Transient entry of enterotoxin subunits into the periplasm occurs during their secretion from Vibrio cholerae

scientific article

Treatment of experimental autoimmune encephalomyelitis by feeding myelin basic protein conjugated to cholera toxin B subunit

scientific article published on July 1996

Ultrastructural localization of cell membrane G M1 ganglioside by cholera toxin ⬇️

scientific article published on September 1, 1977

Vaccination with Bordetella pertussis-pulsed autologous or heterologous dendritic cells induces a mucosal antibody response in vivo and protects against infection

scientific article published on June 2001

Vaccination with dendritic cells pulsed in vitro with tumor antigen conjugated to cholera toxin efficiently induces specific tumoricidal CD8+ cytotoxic lymphocytes dependent on cyclic AMP activation of dendritic cells

scientific article

Vaccine Protection of Bangladeshi infants and young children against cholera: implications for vaccine deployment and person-to-person transmission.

scientific article

Vaccines against enteric infections for the developing world

scientific article

Vaccines against mucosal infections

scientific article published on 12 May 2012

Vibrio cholerae O139 capsular polysaccharide confers complement resistance in the absence or presence of antibody yet presents a productive target for cell lysis: implications for detection of bactericidal antibodies

scientific article published on 7 October 2009

Vibrio cholerae expresses cell surface antigens during intestinal infection which are not expressed during in vitro culture

scientific article

Vibriocidal antibody responses to a bivalent killed whole-cell oral cholera vaccine in a phase III trial in Kolkata, India

scientific article

Virulence factors, pathogenesis and vaccine protection in cholera and ETEC diarrhea

scientific article

Virus-specific antibody production and polyclonal B-cell activation in the intestinal mucosa of HIV-infected individuals

scientific article

Weak serum and intestinal antibody responses to Vibrio cholerae soluble hemagglutinin in cholera patients

scientific article published on September 1984

When, how, and where can oral cholera vaccines be used to interrupt cholera outbreaks?

scientific article published on January 2014

“PERFEXT”: a direct method for quantitative assessment of cytokine production in vivo at the local level ⬇️

scientific article published on 01 May 1997

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