Search filters

List of works by Josep Rizo

A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?

scientific article

A broken alpha -helix in folded alpha -Synuclein

scientific article

A cascade of multiple proteins and lipids catalyzes membrane fusion

scientific article published on March 2017

A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis

scientific article

A conformational switch in the Piccolo C2A domain regulated by alternative splicing

scientific article

A minimal domain responsible for Munc13 activity

scientific article

A protein sequence that can encode native structure by disfavoring alternate conformations

scientific article published on May 2002

A quaternary SNARE-synaptotagmin-Ca2+-phospholipid complex in neurotransmitter release

scientific article published on 23 January 2007

Analysis of SNARE Complex/Synaptotagmin-1 Interactions by One-Dimensional NMR Spectroscopy ⬇️

scientific article published on 07 May 2013

Analysis of asymmetry in lipid and content mixing assays with reconstituted proteoliposomes containing the neuronal SNAREs

scientific article published on 19 February 2020

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

scientific article

At the junction of SNARE and SM protein function

scientific article

Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing

scientific article

Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion.

scientific article published on 6 May 2017

Bimodal-hybrid heterocyclic amine targeting oxidative pathways and copper mis-regulation in Alzheimer's disease

scientific article published on November 2014

Binding of Munc18-1 to synaptobrevin and to the SNARE four-helix bundle

scientific article

Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes

scientific journal article

Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression

scientific article published on December 2010

Cell biology. Staging membrane fusion

scientific article published in Science

Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint

scientific article

Conformational switch of syntaxin-1 controls synaptic vesicle fusion

scientific article

Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins

scientific article

Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution

scientific article

Crystal structure of the RIM2 C2A-domain at 1.4 A resolution

scientific article

Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release

scientific article

Distinct domains of complexin I differentially regulate neurotransmitter release

scientific article published on 9 September 2007

Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus

scientific article

Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution

scientific article

Endocytosis of synaptotagmin 1 is mediated by a novel, tryptophan-containing motif

scientific article

Enlightening molecular mechanisms through study of protein interactions

scientific article

Evidence for SNARE zippering during Ca2+-triggered exocytosis in PC12 cells ⬇️

scientific article published on November 1, 2003

Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release

scientific article published on 18 September 2017

Facile detection of protein-protein interactions by one-dimensional NMR spectroscopy

scientific article published on 01 March 2003

Functional synergy between the Munc13 C-terminal C1 and C2 domains

scientific article published on 23 May 2016

Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release

scientific article

Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis

scientific article

How Tlg2p/syntaxin 16 'snares' Vps45

scientific article

Illuminating membrane fusion

scholarly article

Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer

scientific article

Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1.

scientific article published in February 2005

Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor

scientific article

KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes

scientific article

Measurement of One Bond Dipolar Couplings through Lanthanide-Induced Orientation of a Calcium-Binding Protein

scientific article published in 1999

Mechanism of neurotransmitter release coming into focus

scholarly article by Josep Rizo published in August 2018

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.

scientific article published on 08 February 2017

Membrane Bridging and Hemifusion by Denaturated Munc18 ⬇️

scientific article published on July 6, 2011

Membrane bridging by Munc13-1 is crucial for neurotransmitter release

scientific article published on 28 February 2019

Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.

scientific article

Multiple factors maintain assembled trans-SNARE complexes in the presence of NSF and αSNAP

scholarly article by Eric A Prinslow et al published 18 January 2019 in eLife

Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis

scientific article

Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex ⬇️

scientific article published on April 17, 2011

Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming

scientific article

Munc18-1 binds directly to the neuronal SNARE complex

scientific article

Munc18-1 is crucial to overcome the inhibition of synaptic vesicle fusion by αSNAP

scientific article published on 23 September 2019

NMR analysis of the closed conformation of syntaxin-1.

scientific article published on 6 May 2008

NMR structure and calcium-binding properties of the tellurite resistance protein TerD from Klebsiella pneumoniae

scientific article

NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family

scientific article

Open syntaxin overcomes exocytosis defects of diverse mutants in C. elegans

scientific article published on 02 November 2020

Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1.

scientific article published on 4 April 2006

Preparation and Characterization of Stable α-Synuclein Lipoprotein Particles

scientific article published on 4 February 2016

Prevalent mechanism of membrane bridging by synaptotagmin-1 ⬇️

scientific article published on 05 August 2013

RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes

scientific article published on 29 March 2018

RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction

scientific article

Rabphilin regulates SNARE-dependent re-priming of synaptic vesicles for fusion

scientific article

Re-examining how Munc13-1 facilitates opening of syntaxin-1

scientific article published on 22 February 2020

Re-examining how complexin inhibits neurotransmitter release

scientific article

Reconciling isothermal titration calorimetry analyses of interactions between complexin and truncated SNARE complexes

scientific article published on 7 September 2017

Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release ⬇️

scientific article published on December 20, 2012

Reluctance to membrane binding enables accessibility of the synaptobrevin SNARE motif for SNARE complex formation

scientific article

Remote homology between Munc13 MUN domain and vesicle tethering complexes

scientific article published on 27 June 2009

Reversible protection of lysine to facilitate the purification of protected peptide segments

Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I.

scientific article published in February 2002

Roles of the fission yeast UNC-13/Munc13 protein Ync13 in late stages of cytokinesis.

scientific article published on 25 July 2018

SNARE function revisited

scientific article published on 01 June 2003

SNARE-mediated lipid mixing depends on the physical state of the vesicles

scientific article

Sequence-specific assignment of methyl groups from the neuronal SNARE complex using lanthanide-induced pseudocontact shifts

scientific article published on 17 December 2016

Simultaneous lipid and content mixing assays for in vitro reconstitution studies of synaptic vesicle fusion

scientific article published on 31 August 2017

Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif

scientific journal article

Snares and Munc18 in synaptic vesicle fusion

scientific article (publication date: August 2002)

Solution structure of the RIM1alpha PDZ domain in complex with an ELKS1b C-terminal peptide

scientific journal article

Solution structure of the Vam7p PX domain

scientific article

Structural analysis of conserved oligomeric Golgi complex subunit 2

scientific article

Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7

scientific article

Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch

scientific article

Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4

scientific journal article

Structure and Ca²⁺-binding properties of the tandem C₂ domains of E-Syt2

scientific article

Structure of Antimycin A1, a Specific Electron Transfer Inhibitor of Ubiquinol−CytochromecOxidoreductase

scientific article published in 1999

Subtle Interplay between Synaptotagmin and Complexin Binding to the SNARE Complex ⬇️

scientific article published on July 9, 2013

Synaptic vesicle exocytosis

scientific article

Synaptic vesicle fusion

scientific article published on July 2008

Synaptic vesicle fusion without SNARE transmembrane regions

scientific article

Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cells

scientific article published on 01 July 2002

The Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering Factors

scientific article

The Mad2 spindle checkpoint protein has two distinct natively folded states

scientific article published on 14 March 2004

The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20

scientific article

The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged? ⬇️

scientific article published on January 1, 2012

The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly

scientific article (publication date: 27 September 2002)

The Synaptic Vesicle Release Machinery

scientific article published on June 2015

Three-dimensional structure of the complexin/SNARE complex

scientific article

Three-dimensional structure of the rSly1 N-terminal domain reveals a conformational change induced by binding to syntaxin 5

scientific journal article

UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans

scientific article published on 8 August 2017

Unexpected Ca2+-binding properties of synaptotagmin 9

scientific article

Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release

scientific article

p31comet blocks Mad2 activation through structural mimicry

scientific article

Paulina is supported by:

About Paulina

Help