List of works - Hongjun Fu

3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice

scientific article (publication date: 2016)

A shared disease-associated oligodendrocyte signature among multiple CNS pathologies

scientific article published in 2022

A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

scientific article published on 17 December 2018

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

scientific article published in Nature

Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy

scientific article published on 16 October 2020

Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels

scientific article published on 12 June 2006

Bis(7)-tacrine prevents glutamate-induced excitotoxicity more potently than memantine by selectively inhibiting NMDA receptors.

scientific article published on 6 March 2008

Changes of mandibular movement tracings after the correction of mandibular protrusion by bilateral sagittal split ramus osteotomy.

scientific article published in October 2009

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia ⬇️

scientific article published on March 21, 2012

Effects of selenium on lead-induced alterations in Aβ production and Bcl-2 family proteins.

scientific article published on 10 December 2014

Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.

scientific article published on March 2013

F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease

scientific article

MER5101, a Novel Aβ1-15:DT Conjugate Vaccine, Generates a Robust Anti-Aβ Antibody Response and Attenuates Aβ Pathology and Cognitive Deficits in APPswe/PS1ΔE9 Transgenic Mice ⬇️

scientific article published on April 17, 2013

Mecamylamine prevents neuronal apoptosis induced by glutamate and low potassium via differential anticholinergic-independent mechanisms.

scientific article published on 23 December 2007

Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons.

scientific article

Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: focus on Alzheimer's disease

scientific article published on 12 November 2020

Neuronal activity enhances tau propagation and tau pathology in vivo.

scientific article published on 20 June 2016

Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine

scientific article published in April 2006

Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors

scientific article published on 14 February 2005

Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents

scientific article published on 20 July 2007

Pathologically activated neuroprotection via uncompetitive blockade of N-methyl-D-aspartate receptors with fast off-rate by novel multifunctional dimer bis(propyl)-cognitin

scientific article

Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently

scientific article published on 16 September 2009

Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin

scientific article published on 21 July 2015

Role of synaptic structural plasticity in impairments of spatial learning and memory induced by developmental lead exposure in Wistar rats

scientific article

Selective vulnerability in neurodegenerative diseases

scientific article published on 24 September 2018

Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase.

scientific article

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease.

scientific article published on 13 January 2017

List of works by Hongjun Fu

3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice

A shared disease-associated oligodendrocyte signature among multiple CNS pathologies

A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy

Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels

Bis(7)-tacrine prevents glutamate-induced excitotoxicity more potently than memantine by selectively inhibiting NMDA receptors.

Changes of mandibular movement tracings after the correction of mandibular protrusion by bilateral sagittal split ramus osteotomy.

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia ⬇️

Effects of selenium on lead-induced alterations in Aβ production and Bcl-2 family proteins.

Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.

F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease

MER5101, a Novel Aβ1-15:DT Conjugate Vaccine, Generates a Robust Anti-Aβ Antibody Response and Attenuates Aβ Pathology and Cognitive Deficits in APPswe/PS1ΔE9 Transgenic Mice ⬇️

Mecamylamine prevents neuronal apoptosis induced by glutamate and low potassium via differential anticholinergic-independent mechanisms.

Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons.

Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: focus on Alzheimer's disease

Neuronal activity enhances tau propagation and tau pathology in vivo.

Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine

Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors

Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents

Pathologically activated neuroprotection via uncompetitive blockade of N-methyl-D-aspartate receptors with fast off-rate by novel multifunctional dimer bis(propyl)-cognitin

Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently

Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin

Role of synaptic structural plasticity in impairments of spatial learning and memory induced by developmental lead exposure in Wistar rats

Selective vulnerability in neurodegenerative diseases

Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase.

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease.