List of works - Marko Hyvönen

A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody–drug conjugates

article

Alternative modulation of protein-protein interactions by small molecules

scientific article published on 30 April 2015

Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase-TPX2 protein-protein interaction

scientific article published on 8 August 2017

Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody–drug conjugates

article

Development of a multipurpose scaffold for the display of peptide loops

scientific article published on 24 April 2017

Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction

scientific article published on 11 May 2020

Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein-protein interaction.

scientific article published on 12 April 2019

Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset

article published in the Proceedings of the National Academy of Sciences of the United States of America

Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats

scientific article published on 01 November 2021

Molecular characterization of latent GDF8 reveals mechanisms of activation.

scientific article published on 18 January 2018

Proposed Allosteric Inhibitors Bind to the ATP Site of CK2α

scientific article published on 29 October 2020

Second-generation CK2α inhibitors targeting the αD pocket.

scientific article

Specific inhibition of CK2α from an anchor outside the active site

scientific article published on 12 July 2016

Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2.

scientific article published on 5 June 2017

Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester

scientific article published on 16 February 2018

Structure of the human myostatin precursor and determinants of growth factor latency.

scientific article published on 12 January 2018

Structure of the human pro-myostatin precursor and determinants of growth factor latency

The thrombospondin module 1 domain of the matricellular protein CCN3 shows an atypical disulfide pattern and incomplete CWR layers

scientific article published on 24 January 2020

Two-Component Stapling of Biologically Active and Conformationally Constrained Peptides: Past, Present, and Future

scholarly article published 7 August 2018

Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry

scientific article published on 01 August 2019

List of works by Marko Hyvönen