List of works by Richard G Grundy

A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor

scientific article published on 01 July 2019

A common polymorphism in the 5' UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy

scientific article

A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma

scientific article published on 16 July 2019

Application of pattern recognition techniques for classification of pediatric brain tumors by in vivo 3T (1) H-MR spectroscopy-A multi-center study

scientific article published on 08 August 2017

Assessing 'second-look' tumour resectability in childhood posterior fossa ependymoma-a centralised review panel and staging tool for future studies.

scientific article

Chemical modulation of autophagy as an adjunct to chemotherapy in childhood and adolescent brain tumors

scientific article published on 16 October 2018

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

scientific article published on 25 June 2015

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

scientific article published in 2021

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease

scientific article published on 21 January 2017

Distinguishing between paediatric brain tumour types using multi-parametric magnetic resonance imaging and machine learning: A multi-site study

scientific article published on 23 January 2020

EMBR-15. DIAGNOSTIC RE-EVALUATION AND POOLED CLINICAL DATA ANALYSIS OF PATIENTS WITH PREVIOUS DIAGNOSIS OF CNS-PNET

EPEN-10. ROLE OF DNA METHYLATION ANALYSIS IN RECURRENT PAEDIATRIC EPENDYMOMA.

scientific article published on 22 June 2018

EPEN-23. MOLECULAR HETEROGENEITY AMONG PEDIATRIC POSTERIOR FOSSA EPENDYMOMA

EPND-07. MOLECULAR HETEROGENEITY AMONG PEDIATRIC POSTERIOR FOSSA EPENDYMOMA.

scientific article published on 31 May 2017

Electrical impedance tomography effectively used in a case of paediatric pulmonary Langerhans cell histiocytosis

scientific article published on 05 September 2018

Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response

scientific article

Germline mutations and somatic inactivation of TRIM28 in Wilms tumour.

scientific article published on 18 June 2018

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

scientific article

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification

scientific article

Metabolite Levels in Paediatric Brain Tumours Correlate with Histological Features

scientific article published on 10 February 2018

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

scientific article published on 28 January 2016

Modulating autophagy as a therapeutic strategy for the treatment of paediatric high-grade glioma

scientific article published on 13 May 2019

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas

scientific article published on 16 June 2018

Neurocognitive, academic and functional outcomes in survivors of infant ependymoma (UKCCSG CNS 9204)

scientific article published on 15 December 2018

OP05FUNCTIONAL ANALYSIS OF MULTI-DRUG RESISTANCE TRANSPORTER ABCB1 WHICH CORRELATES WITH POOR PROGNOSIS IN PAEDIATRIC EPENDYMOMA.

scientific article published on 17 November 2015

OP12NEW TOOLS TO STUDY HISTONE H3.3 MUTATIONS IN DIPG AND PHGG.

scientific article

OP22SIMULTANEOUS INTRA-CAVITY DELIVERY OF MULTIPLE CHEMOTHERAPEUTICS FROM A MOULDABLE NEUROSURGICALLY-APPLIED POLYMER PASTE.

scientific article

OP24ASSESSING 'SECOND-LOOK' TUMOUR RESECTABILITY IN CHILDHOOD EPENDYMOMA - A CENTRALISED REVIEW PANEL AND CLASSIFICATION TOOL FOR THE SIOP EPENDYMOMA II TRIAL.

scientific article

Outcomes of non-anaplastic stage III and 'inoperable' Wilms tumour treated in the UKW3 trial

scientific article published on 15 December 2018

Overall Survival in Malignant Glioma Is Significantly Prolonged by Neurosurgical Delivery of Etoposide and Temozolomide from a Thermo-Responsive Biodegradable Paste

scientific article published on 21 May 2019

PATH-32. MOLECULAR HETEROGENEITY AMONG PEDIATRIC POSTERIOR FOSSA EPENDYMOMA

PO10AN INVESTIGATION INTO THE POTENTIAL OF THE KETOGENIC DIET IN THE CELLULAR METABOLISM OF PAEDIATRIC BRAIN TUMOURS.

scientific article

PO32GENE CO-EXPRESSION NETWORK ANALYSIS REVEALS UNIQUE MOLECULAR CHARACTERISTICS GOVERNING THE MARGINS OF GLIOBLASTOMA.

scientific article

PO38INVESTIGATING THE ROLE THE PI3K PATHWAY PLAYS IN EPENDYMOMA PATHOGENESIS.

scientific article

PO43TRI-METHYLATED HISTONE H3K27 LEVELS ARE ASSOCIATED WITH LOCATION, AGE AND SURVIVAL.

scientific article

PO44INVESTIGATION OF THE CLINICAL POTENTIAL OF AGENTS TARGETING EPIGENETIC MODIFICATIONS IN PAEDIATRIC EPENDYMOMA.

scientific article

PO45A SYSTEMATIC REVIEW STRATEGY IDENTIFIES CHEMOTHERAPEUTIC CANDIDATES FOR EFFICACIOUS INTRA-CRANIAL DELIVERY IN GLIOBLASTOMA.

scientific article

PO48CHARACTERISING INTRATUMOUR HETEROGENEITY IN PAEDIATRIC GLIOBLASTOMA MULTIFORME USING A NOVEL ADVANCED MASS SPECTROMETRY TECHNIQUE.

scientific article

PO70COMPARISON OF THE TRANSCRIPTIONAL LANDSCAPES OF POSTERIOR FOSSA EPENDYMOMA ACROSS AGE GROUPS.

scientific article

PO72MGMT EXPRESSION, PROMOTER METHYLATION AND CIRCUMVENTION IN EPENDYMOMAS.

scientific article

Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study

scientific article published on 09 December 2019

Prospective multicentre evaluation and refinement of an analysis tool for magnetic resonance spectroscopy of childhood cerebellar tumours

scientific article published on 30 July 2018

Proton beam therapy for medulloblastoma.

scientific article published on 27 April 2016

Radiomics in paediatric neuro-oncology: A multicentre study on MRI texture analysis.

scientific article published on 26 October 2017

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

scientific article published on 05 August 2021

Switching from linear to macrocyclic gadolinium-based contrast agents halts the relative T1 -Weighted signal increase in deep gray matter of children with brain tumors: A retrospective study

scientific article published on 04 June 2019

The European Society of Paediatric Oncology Ependymoma-II program Core-Plus model: Development and initial implementation of a cognitive test protocol for an international brain tumour trial

scientific article published on 18 May 2019

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants

scientific article

The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors

scientific article

Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours

scientific article published in Scientific Reports

Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures.

scientific article published on 14 December 2017

Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.

scientific article published on 14 March 2018

Vascular stenosis in a child with visual pathway glioma treated with bevacizumab: a case report and review of literature

scientific article published on 16 December 2017

Paulina is supported by:

About Paulina

Help