List of works - Julie Charton

A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening

scientific article

A versatile solid-phase synthesis of 3-aryl-1,2,4-oxadiazolones and analogues

Access to newly functionalized imidazole derivatives: efficient synthesis of novel 5-amino-2-thioimidazoles using propylphosphonic anhydride (®T3P)

Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds

scientific article

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

scientific article

Characterization of monoclonal antibodies by a fast and easy liquid chromatography-mass spectrometry time-of-flight analysis on culture supernatant

scientific article published on 21 August 2015

Convenient synthesis of 4H-1,2,4-triazole-3-thiols using di-2-pyridylthionocarbonate

Convenient synthesis of tetrahydroisoquinoline-hydantoins

article published in 2001

Conversion of sterically hindered diacylated 1,2-phenylenediamines into 2-substituted benzimidazoles

scientific article published in May 2005

Determination of pKa values of benzimidazole derivatives from mobility obtained by capillary electrophoresis

scientific article published on 27 July 2010

Development of HPLC/fluorescence detection method for chiral resolution of dansylated benzimidazoles derivatives

scientific article

Drug to Genome to Drug: Discovery of New Antiplasmodial Compounds

scientific article published on 19 April 2011

Drug-to-genome-to-drug, step 2: reversing selectivity in a series of antiplasmodial compounds

scientific article

Enantioseparation of chiral benzimidazole derivatives by electrokinetic chromatography using sulfated cyclodextrins.

scientific article published in June 2009

Hydroxamates: relationships between structure and plasma stability

scientific article published in November 2009

Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis

scientific article

Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives

scientific article

Optimized synthesis of tetrahydroisoquinoline-hydantoins

Preparative enantiomeric separation of potent AMP-activated protein kinase activator by HPLC on amylose-based chiral stationary phase. Determination of enantiomeric purity and assignment of absolute configuration

scientific article

Single and dual cyclodextrins systems for the enantiomeric and diastereoisomeric separations of structurally related dihydropyridone analogues

scientific article published on 22 April 2017

Squaric acid is a suitable building-block in 4C-Ugi reaction: access to original bivalent compounds

Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.

scientific article

Supercritical fluid chromatography versus high performance liquid chromatography for enantiomeric and diastereoisomeric separations on coated polysaccharides-based stationary phases: Application to dihydropyridone derivatives

scientific article published on 19 March 2018

Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators

scientific article published on 2 March 2006

Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective sigma1 ligands. Part 2.

scientific article published in November 2005

Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective σ1 ligands. Part 1

scientific article published on 01 November 2005

Synthesis of a 200-member library of squaric acid N-hydroxylamide amides

scientific article

The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity

scientific article published on 28 July 2015

Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance

scientific article published on 17 April 2017

List of works by Julie Charton

A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening

A versatile solid-phase synthesis of 3-aryl-1,2,4-oxadiazolones and analogues

Access to newly functionalized imidazole derivatives: efficient synthesis of novel 5-amino-2-thioimidazoles using propylphosphonic anhydride (®T3P)

Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds

Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice

Characterization of monoclonal antibodies by a fast and easy liquid chromatography-mass spectrometry time-of-flight analysis on culture supernatant

Convenient synthesis of 4H-1,2,4-triazole-3-thiols using di-2-pyridylthionocarbonate

Convenient synthesis of tetrahydroisoquinoline-hydantoins

Conversion of sterically hindered diacylated 1,2-phenylenediamines into 2-substituted benzimidazoles

Determination of pKa values of benzimidazole derivatives from mobility obtained by capillary electrophoresis

Development of HPLC/fluorescence detection method for chiral resolution of dansylated benzimidazoles derivatives

Drug to Genome to Drug: Discovery of New Antiplasmodial Compounds

Drug-to-genome-to-drug, step 2: reversing selectivity in a series of antiplasmodial compounds

Enantioseparation of chiral benzimidazole derivatives by electrokinetic chromatography using sulfated cyclodextrins.

Hydroxamates: relationships between structure and plasma stability

Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis

Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives

Optimized synthesis of tetrahydroisoquinoline-hydantoins

Preparative enantiomeric separation of potent AMP-activated protein kinase activator by HPLC on amylose-based chiral stationary phase. Determination of enantiomeric purity and assignment of absolute configuration

Single and dual cyclodextrins systems for the enantiomeric and diastereoisomeric separations of structurally related dihydropyridone analogues

Squaric acid is a suitable building-block in 4C-Ugi reaction: access to original bivalent compounds

Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.

Supercritical fluid chromatography versus high performance liquid chromatography for enantiomeric and diastereoisomeric separations on coated polysaccharides-based stationary phases: Application to dihydropyridone derivatives

Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators

Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective sigma1 ligands. Part 2.

Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective σ1 ligands. Part 1

Synthesis of a 200-member library of squaric acid N-hydroxylamide amides

The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity

Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance