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List of works by Heike Bickeböller

"Tradition is not preserving the ashes, it is passing on the fire". On strengthening ties with GMDS.

scientific article

A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia

scientific article

A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma

scientific article published on 10 June 2011

A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer

scientific article published on 07 October 2016

A common MLP (muscle LIM protein) variant is associated with cardiomyopathy

scientific article

A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease.

scientific article published on 6 July 2006

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

scientific article

A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers

scientific article published on 30 December 2008

A network-based kernel machine test for the identification of risk pathways in genome-wide association studies

scientific article

A novel kernel for correcting size bias in the logistic kernel machine test with an application to rheumatoid arthritis

scientific article published on January 2012

Abstract 4597: A novel variant in DNA repair gene GTF2H4 is associated with lung cancer risk: A reanalysis of GWAS datasets from the TRICL consortium

article

Analysis of principal component based quantitative phenotypes for alcoholism

scientific article published on 01 January 1999

Angiotensin converting enzyme gene polymorphism and myocardial infarction a large association and linkage study

scientific article published in June 2003

Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex

scientific article

Application of genomewide SNP arrays for detection of simulated susceptibility loci

scientific article published in June 2005

Aspirin and NSAID use and lung cancer risk: a pooled analysis in the International Lung Cancer Consortium (ILCCO).

scientific article published on 11 October 2011

Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

scientific article

Association of HLA-E polymorphism with the outcome of hematopoietic stem-cell transplantation with unrelated donors.

scientific article

Association of beta(2)-adrenoreceptor variants with bronchial hyperresponsiveness.

scientific article

Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs

scientific article published on 17 March 2017

Asthma and lung cancer risk: a systematic investigation by the International Lung Cancer Consortium

scientific article

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis

scientific article published in May 2015

CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences

scientific article

Case-control association tests correcting for population stratification

scientific article published on 01 January 2006

Case-control studies with affected sibships.

scientific article

Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study

scientific article published on 31 October 2017

Comparing strategies for combined testing of rare and common variants in whole sequence and genome-wide genotype data

scientific article

Comparing the power of linkage detection by the transmission disequilibrium test and the identity-by-descent test

article

Comparison of pathway analysis approaches using lung cancer GWAS data sets

scientific article

Comparison of three summary statistics for ranking genes in genome-wide association studies.

scientific article published on 9 December 2013

Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia.

scientific article published on 19 April 2010

Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R

scientific article

Correlation of Hsp70-1 and Hsp70-2 gene expression with the degree of graft-versus-host reaction in a rat skin explant model

scientific article published on 01 June 2008

Coverage and efficiency in current SNP chips.

scientific article published on 22 January 2014

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer

scientific article

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

scientific article

Dealing with high dimensionality for the identification of common and rare variants as main effects and for gene-environment interaction

scientific article published in January 2011

Detecting responses to treatment with fenofibrate in pedigrees

article

Detection of ATM gene mutations in young lung cancer patients: a population-based control study

scientific article published on 31 October 2007

Dissection of heterogeneous phenotypes for quantitative trait mapping.

scientific article published in January 2005

Dissociation of accumulated genetic risk and disease severity in patients with schizophrenia

scientific article published on 4 October 2011

Distribution of genome shared IBD by half-sibs: approximation by the Poisson clumping heuristic.

scientific article published on August 1996

Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years

scientific article

Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene

scientific article

Empirical hierarchical bayes approach to gene-environment interactions: development and application to genome-wide association studies of lung cancer in TRICL.

scientific article published on 26 July 2013

Erratum to: Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

scientific article

Fine mapping and single nucleotide polymorphism association results of candidate genes for asthma and related phenotypes.

scientific article

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

scientific article published in Nature Communications

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 ⬇️

scientific article

Functional impact of endotoxin receptor CD14 polymorphisms on transcriptional activity.

scientific article published on 27 May 2009

Functional variants in DCAF4 associated with lung cancer risk in European populations

scientific article published on 5 April 2017

GENESTAT: an information portal for design and analysis of genetic association studies

scientific article (publication date: April 2009)

GPC5 rs2352028 variant and risk of lung cancer in never smokers

scientific article published in August 2010

Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report

scientific article

Gene-set meta-analysis of lung cancer identifies pathway related to systemic lupus erythematosus

scientific article

Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans

scientific article (publication date: 30 December 2005)

Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci

scientific article

Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses

scientific article

Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

scientific article

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis

scientific article published on 10 August 2016

Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians

scientific article published in February 1999

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

scientific article

Genetic factors in individual radiation sensitivity

scientific article published on 4 March 2014

Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners

journal article published in 2018

Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer

scientific article published in October 2010

Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium

scientific article published on 10 June 2016

Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

scientific article

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

scientific article published on 20 October 2017

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence

scientific article published on 06 October 2015

German cattle allergy study (CAS): public health relevance of cattle-allergic farmers

scientific article published on 17 July 2007

Heritability of radiation response in lung cancer families

scientific article

Hidden population substructures in an apparently homogeneous population bias association studies

scientific article

Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

scientific article published on February 2013

High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11

scientific article published on 07 September 2004

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

scientific article

Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions

scientific article

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

scientific article published in Nature Communications

Identifying rare variants from exome scans: the GAW17 experience

scientific article

Impact of HLA-DPB1 allelic and single amino acid mismatches on HSCT.

scientific article

Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia.

scientific article

Impact of genomic risk factors on survival after haematopoietic stem cell transplantation for patients with acute leukaemia.

scientific article published on 9 November 2016

Impact of the MICA-129Met/Val Dimorphism on NKG2D-Mediated Biological Functions and Disease Risks

scientific article

Inclusion of a priori information in genome-wide association analysis

scientific article (publication date: 2009)

Incorporating larger families in identity-by-descent based linkage analysis

scientific article published on 01 January 1999

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

scientific article

Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium

scientific article

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

scientific article

Informed conditioning on clinical covariates increases power in case-control association studies

scientific article published on 8 November 2012

Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer

scientific article

Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia

scientific article published on 12 July 2017

Integration of a priori gene set information into genome-wide association studies

scientific article

Interferon regulatory factor-1 promoter polymorphism and the outcome of hepatitis C virus infection.

scientific article published in September 2006

International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants

scientific article

Inverse relationship between cerebrovascular lesions and severity of lewy body pathology in patients with lewy body diseases

scientific article published in May 2010

Investigating the genetic relationship between Alzheimer's disease and cancer using GWAS summary statistics

scientific article published on 5 August 2017

Investigation of the candidate genes ACTHR and golf for bipolar illness by the transmission/disequilibrium test

scientific article published on 01 January 1997

Issues in association mapping with high-density SNP data and diverse family structures

scientific article

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation

scientific article published on 26 January 2009

Kernel score statistic for dependent data

scientific article

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

scientific article published on 12 June 2017

Linkage analysis of Alzheimer's disease with methods using relative pairs

scientific article published in January 1993

Linkage analysis of malignant melanoma with the chromosome 1 markers D1S47 and PND

scientific article published on 01 January 1992

META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies

scientific article

Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer

scientific article published in May 2008

Meta analysis of whole-genome linkage scans with data uncertainty: an application to Parkinson's disease

scientific article

Minor ABO-mismatches are risk factors for acute graft-versus-host disease in hematopoietic stem cell transplant patients

scientific article published in November 2009

Modeling and dissection of longitudinal blood pressure and hypertension phenotypes in genetic epidemiological studies

scientific article published in January 2003

Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms

scientific article published in September 2010

NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity

scientific article

Nonparametric longitudinal allele-sharing model

scientific article

Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk

scientific article

Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer

scientific article published on 26 October 2017

OUP accepted manuscript

article published 2018 in International Journal of Epidemiology

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

scientific article published on 8 June 2017

Odor naming and interpretation performance in 881 schizophrenia subjects: association with clinical parameters

scientific article

Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies

scientific article published on 13 July 2017

Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus

scientific article

Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia

scientific article published on 27 June 2017

Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls

scientific article published on 10 February 2016

Post-genome respiratory epidemiology: a multidisciplinary challenge

scientific article published in September 2004

Predicting survival using clinical risk scores and non-HLA immunogenetics.

scientific article published on 27 July 2015

Prevention, Diagnosis, Therapy, and Follow-up of Lung Cancer

scientific article published on 14 December 2010

Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium

scientific article

Protein-altering germline mutations implicate novel genes related to lung cancer development

scientific article published on 11 May 2020

Prävention, Diagnostik, Therapie und Nachsorge des Lungenkarzinoms

scientific article published on 09 March 2010

Prävention, Diagnostik, Therapie und Nachsorge des Lungenkarzinoms

scientific article published in August 2011

Quantifying the contribution of genetic variants for survival phenotypes

article

Relating drug response to epigenetic and genetic markers using a region-based kernel score test

scientific article published on 17 September 2018

Relationship of Apolipoprotein E and Age at Onset to Parkinson Disease Neuropathology

scientific article published on 01 February 2006

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium

scientific article

Shared heritability and functional enrichment across six solid cancers

Significant association of a M129V independent polymorphism in the 5' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study

scientific article published in October 2006

Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markers

article

Strategy for Detecting Susceptibility Genes with Weak or No Marginal Effect

article

Surrogate phenotype definition for alcohol use disorders: a genome-wide search for linkage and association.

scientific article published on 30 December 2005

Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk - a re-analysis of eight GWASs

scientific article (publication date: 15 November 2016)

Systematic search for susceptibility genes in different populations

scientific article published on 01 January 1999

Systematic search of susceptibility loci with methods using gametic disequilibrium

scientific article published on 01 January 1995

Tests for candidate-gene interaction for longitudinal quantitative traits measured in a large cohort

scientific article

The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation

scientific article

The National Genome Research Network. Genome research in Germany

scientific article published in February 2007

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

scientific article published on 03 October 2016

The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells.

scientific article published on April 2010

The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands

scientific article

The longitudinal nonparametric test as a new tool to explore gene-gene and gene-time effects in cohorts

article

The probability distribution of the amount of an individual's genome surviving to the following generation

scientific article

The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response

scientific article

Validation of a fully automated COMET assay: 1.75 million single cells measured over a 5 year period

scientific article published on 14 January 2011

Weighting schemes in pooled linkage analysis.

scientific article published in January 2001

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