List of works - Jie Luo

A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

scientific article published on 01 June 2018

AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

scientific article published on 4 January 2017

Ablation of Type III Adenylyl Cyclase in Mice Causes Reduced Neuronal Activity, Altered Sleep Pattern, and Depression-like Phenotypes

scientific article published on 19 December 2015

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.

scientific article published on 12 June 2017

Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins

scientific article published on 22 May 2019

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2

scientific article published on 17 January 2020

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

scientific article published in Nature Communications

Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease

scientific article published on 10 August 2020

Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis

scientific article published on 11 November 2020

Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome.

scientific article published on 30 August 2016

Inhibition of the sterol regulatory element-binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

scientific article published on 27 December 2016

Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites

scientific article published on 08 November 2018

Measurement of Cholesterol Transfer from Lysosome to Peroxisome Using an In Vitro Reconstitution Assay

scientific article published on 01 January 2017

Mechanisms and regulation of cholesterol homeostasis

scientific article published on 17 December 2019

Numb directs the subcellular localization of EAAT3 through binding the YxNxxF motif.

scientific article published on 29 June 2016

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.

scientific article published on 20 January 2018

POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

scientific article published on 14 July 2020

Phosphorylation of eukaryotic translation initiation factor 4E and eukaryotic translation initiation factor 4E-binding protein (4EBP) and their upstream signaling components undergo diurnal oscillation in the mouse hippocampus: implications for [...]

scientific article

Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.

scientific article published on 26 January 2018

Routes and mechanisms of post-endosomal cholesterol trafficking: A story that never ends.

scientific article published on 13 February 2017

SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1

scientific article published on 05 November 2020

Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase

scientific article published on 19 July 2019

Subventricular zone-mediated ependyma repair in the adult mammalian brain.

scientific article published on April 2008

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes.

scientific article published in June 2017

The aging neurogenic subventricular zone.

scientific article

The non-canonical NF-κB pathway promotes NPC2 expression and regulates intracellular cholesterol trafficking

scientific article published on 07 August 2018

The type 3 adenylyl cyclase is required for the survival and maturation of newly generated granule cells in the olfactory bulb

scientific article

List of works by Jie Luo

A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

Ablation of Type III Adenylyl Cyclase in Mice Causes Reduced Neuronal Activity, Altered Sleep Pattern, and Depression-like Phenotypes

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.

Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease

Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis

Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome.

Inhibition of the sterol regulatory element-binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites

Measurement of Cholesterol Transfer from Lysosome to Peroxisome Using an In Vitro Reconstitution Assay

Mechanisms and regulation of cholesterol homeostasis

Numb directs the subcellular localization of EAAT3 through binding the YxNxxF motif.

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.

POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

Phosphorylation of eukaryotic translation initiation factor 4E and eukaryotic translation initiation factor 4E-binding protein (4EBP) and their upstream signaling components undergo diurnal oscillation in the mouse hippocampus: implications for [...]

Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.

Routes and mechanisms of post-endosomal cholesterol trafficking: A story that never ends.

SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1

Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase

Subventricular zone-mediated ependyma repair in the adult mammalian brain.

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes.

The aging neurogenic subventricular zone.

The non-canonical NF-κB pathway promotes NPC2 expression and regulates intracellular cholesterol trafficking

The type 3 adenylyl cyclase is required for the survival and maturation of newly generated granule cells in the olfactory bulb