List of works - Christopher Tynan

3D visualization of additive occlusion and tunable full-spectrum fluorescence in calcite ⬇️

scientific article

A tale of the epidermal growth factor receptor: The quest for structural resolution on cells.

scientific article

A ‘pocket guide’ to total internal reflection fluorescence ⬇️

scientific article published on July 24, 2013

Automated multidimensional single molecule fluorescence microscopy feature detection and tracking.

scientific article

Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor

article

Determining the geometry of oligomers of the human epidermal growth factor family on cells with 7 nm resolution.

scientific article published on 18 April 2015

Determining the geometry of oligomers of the human epidermal growth factor family on cells with <10 nm resolution.

scientific article published on June 2015

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

scientific article

Human epidermal growth factor receptor (EGFR) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry

scientific article published on 28 March 2011

Hydrophobic fluorescent probes introduce artifacts into single molecule tracking experiments due to non-specific binding

scientific article

Investigating extracellular in situ EGFR structure and conformational changes using FRET microscopy.

scientific article

Nanometric molecular separation measurements by single molecule photobleaching.

scientific article published on 14 May 2015

Optics clustered to output unique solutions: a multi-laser facility for combined single molecule and ensemble microscopy.

scientific article

Self-association of calcium-binding protein S100A4 and metastasis

scientific article

Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.

scientific article

Structure-function relationships and supramolecular organization of the EGFR (epidermal growth factor receptor) on the cell surface.

scientific article published on February 2014

The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers

scientific article published in Nature Communications

List of works by Christopher Tynan

3D visualization of additive occlusion and tunable full-spectrum fluorescence in calcite ⬇️

A tale of the epidermal growth factor receptor: The quest for structural resolution on cells.

A ‘pocket guide’ to total internal reflection fluorescence ⬇️

Automated multidimensional single molecule fluorescence microscopy feature detection and tracking.

Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor

Determining the geometry of oligomers of the human epidermal growth factor family on cells with 7 nm resolution.

Determining the geometry of oligomers of the human epidermal growth factor family on cells with <10 nm resolution.

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

Human epidermal growth factor receptor (EGFR) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry

Hydrophobic fluorescent probes introduce artifacts into single molecule tracking experiments due to non-specific binding

Investigating extracellular in situ EGFR structure and conformational changes using FRET microscopy.

Nanometric molecular separation measurements by single molecule photobleaching.

Optics clustered to output unique solutions: a multi-laser facility for combined single molecule and ensemble microscopy.

Self-association of calcium-binding protein S100A4 and metastasis

Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.

Structure-function relationships and supramolecular organization of the EGFR (epidermal growth factor receptor) on the cell surface.

The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers