Search filters

List of works by Graham Le Gros

A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development

scientific article published on 22 March 2018

Absence of airway inflammation in a large proportion of adolescents with asthma

scientific article

Absence of preproenkephalin increases the threshold for T cell activation

scientific article published in July 2003

Activation of p38 MAP kinase in T cells facilitates the immune response to the influenza virus.

scientific article published in June 2000

Allergen-specific CTL require perforin expression to suppress allergic airway inflammation

scientific article published on 16 January 2012

Allergic airway inflammation is exacerbated during acute influenza infection and correlates with increased allergen presentation and recruitment of allergen-specific T-helper type 2 cells.

scientific article published in August 2004

Analysis of two IL-4 promoter polymorphisms in a cohort of atopic and asthmatic subjects

scientific article published on 01 January 1999

Annotated mitochondrial genome with Nanopore R9 signal for Nippostrongylus brasiliensis.

scientific article

Antibodies and IL-3 support helminth-induced basophil expansion.

scientific article

Association of beta2-adrenergic receptor polymorphisms with severe asthma

scientific article published on 01 August 2000

Basophils Are the Major Producers of IL-4 during Primary Helminth Infection ⬇️

scientific article published on January 26, 2011

Blimp-1 induced by IL-4 plays a critical role in suppressing IL-2 production in activated CD4 T cells

scientific article published on 01 October 2008

Blockade of CD28/B7 co-stimulation by mCTLA4-Hgamma1 inhibits antigen-induced lung eosinophilia but not Th2 cell development or recruitment in the lung

article

Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells

scholarly article

CD326(lo)CD103(lo)CD11b(lo) dermal dendritic cells are activated by thymic stromal lymphopoietin during contact sensitization in mice

scientific article published on 23 July 2014

CD8+ T cells and immunoregulatory networks in asthma.

scientific article published on 18 October 2003

CD80 costimulation is essential for the induction of airway eosinophilia

scientific article published on January 1997

Can bacterial endotoxin exposure reverse atopy and atopic disease?

scientific article published on November 2004

Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection

scientific article (publication date: March 2015)

Constitutive expression of interleukin 4 in vivo does not lead to the development of T helper 2 type CD8+ T cells secreting interleukin 4 or interleukin 5

scientific article published on 01 June 1999

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells

scientific article

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) can regulate dendritic cell-induced activation and cytotoxicity of CD8(+) T cells independently of CD4(+) T cell help.

scientific article published on April 1999

De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads

scientific article published on 11 January 2018

Dermal group 2 innate lymphoid cells in atopic dermatitis and allergy.

scientific article published on 28 October 2014

Development of CD4 T Cell Dependent Immunity Against N. brasiliensis Infection

scientific article published on 20 March 2013

Development of an asthma vaccine: research into BCG.

scientific article

Differential requirements for IL-4/STAT6 signalling in CD4 T-cell fate determination and Th2-immune effector responses

scientific article published on 15 December 2009

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

scientific article published in March 1993

Effector lymphoid tissue and its crucial role in protective immunity.

scientific article published in May 2005

Eosinophils Determine Dermal Thickening and Water Loss in an MC903 Model of Atopic Dermatitis

scientific article published on 30 June 2018

Epigenetic regulation of Th2 cytokine expression in atopic diseases.

scientific article published on 28 June 2008

Evaluating the in vivo Th2 priming potential among common allergens

scientific article published on 17 May 2013

Expression of receptors for atrial natriuretic peptide on the murine bone marrow-derived stromal cells

scientific article published on May 1, 1992

Farm exposure in utero may protect against asthma, hay fever and eczema.

scientific article

Genetic regulation of antibody responsiveness to immunization in substrains of BALB/c mice

scientific article published on 14 October 2018

Growth of fetal thymocytes in organ culture: effect of recombinant lymphokines on thymocyte maturation

scientific article published on 01 January 1989

Helminth-conditioned dendritic cells prime CD4+ T cells to IL-4 production in vivo.

scientific article published on 8 August 2014

High-dimensional analysis of intestinal immune cells during helminth infection

scientific article published on 11 February 2020

Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps

scientific article published on 01 February 2020

How epigenetic imprinting contributes to stabilizing the Th2 phenotype ⬇️

scientific article published on September 25, 2012

IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation

scientific article published on 27 May 2015

IL-25 exhibits disparate roles during Th2-cell differentiation versus effector function

scientific article published on 19 May 2014

IL-4 Derived from Non-T Cells Induces Basophil- and IL-3-independent Th2 Immune Responses

scientific article published on 20 December 2013

IL-4 Haploinsufficiency Specifically Impairs IgE Responses against Allergens in Mice.

scientific article published on 23 January 2017

IL-4 Is a Key Requirement for IL-4- and IL-4/IL-13-Expressing CD4 Th2 Subsets in Lung and Skin.

scientific article

IL-4 differentiates naive CD8+ T cells to a "Th2-like" phenotype: a link between viral infections and bronchial asthma.

scientific article

IL-4, IL-5 and IL-10 are not required for the control of M. bovis-BCG infection in mice

scientific article published on 01 February 1998

ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms.

scientific article published on 27 April 2015

ILC2s-Trailblazers in the Host Response Against Intestinal Helminths

scientific article published on 04 April 2019

Immature murine NKT cells pass through a stage of developmentally programmed innate IL-4 secretion.

scientific article published on 31 August 2012

Immunity without innate lymphoid cells.

scientific article published in October 2016

In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation

scholarly article

Increased frequency of interleukin 4-producing T cells as a result of polyclonal priming. Use of a single-cell assay to detect interleukin 4-producing cells ⬇️

scientific article published on May 1, 1991

Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils

scientific article published on 01 April 2007

Interleukin-3-treated non-B, non-T cells switch activated B cells to IgG1/IgE synthesis

scientific article published on 01 November 1992

Interleukin-4 is required for the induction of lung Th2 mucosal immunity

scientific article published on 01 July 1995

Intestinal helminth infection promotes IL-5- and CD4 T cell-dependent immunity in the lung against migrating parasites

scientific article published on 06 November 2018

Large Particle Sorting to Isolate Live Parasitic Nematode Eggs.

scientific article published in April 2016

Lifelong farm exposure may strongly reduce the risk of asthma in adults.

scientific article

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden.

scientific article

Mast cells in the front line. Innate immunity

scientific article published on August 1996

Mechanistic studies of copper(I)-catalyzed 1,3-halogen migration

scientific article

Mucosal trapping and degradation of Nippostrongylus brasiliensis occurs in the absence of STAT6.

scientific article published on 27 February 2013

Mycobacterium-based vaccines for the prevention of allergic disease: a progress report

scientific article published on 01 August 2002

New concepts of IgE regulation

scientific article published on January 1991

Non-cytotoxic, IL-4, IL-5, IL-10 producing CD8+ T cells: their activation and effector functions.

scientific article published on June 1994

Nuclear factor of activated T (NFAT) cells activity within CD4+ T cells is influenced by activation status and tissue localisation

scientific article published on 12 September 2005

Preproenkephalin is a Th2 cytokine but is not required for Th2 differentiation in vitro

scientific article published on 01 October 1999

Production of interleukin-4 and other cytokines following stimulation of mast cell lines and in vivo mast cells/basophils.

scientific article published on January 1991

Role of interleukin 2 and interleukin 3 in haemopoiesis ⬇️

1987 doctoral thesis by Graham Stephen Le Gros at University of Auckland

Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis

scientific article

Secretory products from infective forms of Nippostrongylus brasiliensis induce a rapid allergic airway inflammatory response.

scientific article published in February 2005

Serum levels of interleukins 8 and 10, interferon gamma, granulocyte-macrophage colony stimulating factor and soluble CD23 in patients with primary sclerosing cholangitis

scientific article published in January 1997

Staphylococcal‐derived superantigen enhances peanut induced Th2 responses in the skin ⬇️

scientific article published on September 21, 2011

Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells.

scientific article

T cell-derived IL-3 plays key role in parasite infection-induced basophil production but is dispensable for in vivo basophil survival.

scientific article

Th2-dependent airway eosinophilia is regulated by preproenkephalin

scientific article published on 01 July 2000

Th2-like CD8 T cells: their role in protection against infectious diseases

scientific article published on 01 August 1994

The Basoph8 Mice Enable an Unbiased Detection and a Conditional Depletion of Basophils

scientific article published on 10 September 2019

The Differentiation of CD4(+) T-Helper Cell Subsets in the Context of Helminth Parasite Infection

scientific article

The Gastrointestinal Helminth Heligmosomoides bakeri Suppresses Inflammation in a Model of Contact Hypersensitivity

scientific article published on 19 May 2020

The Study of Host Immune Responses Elicited by the Model Murine Hookworms Nippostrongylus brasiliensis and Heligmosomoides polygyrus

scientific article published on 20 December 2017

The effect of delipidated deglycolipidated (DDMV) and heat-killed Mycobacterium vaccae in asthma

scientific article published on 01 May 2001

The lung is an important site for priming CD4 T-cell-mediated protective immunity against gastrointestinal helminth parasites

scientific article

The role of CTLA-4 in the regulation of T cell immune responses.

scientific article

The role of ILC2 in hookworm infection.

scientific article

Thymic stromal lymphopoietin drives the development of IL-13+ Th2 cells.

scientific article published on 16 January 2018

Tissue localization and frequency of antigen-specific effector CD4 T cells determines the development of allergic airway inflammation

scientific article published in October 2005

Toll-Like Receptor 4, but Not Neutrophil Extracellular Traps, Promote IFN Type I Expression to Enhance Th2 Responses to Nippostrongylus brasiliensis

scientific article published on 16 November 2017

Which is the true regulator of TH2 cell development in allergic immune responses? ⬇️

scientific article published on 01 August 1998

Paulina is supported by:

About Paulina

Help