List of works by Thomas R. Kozel

A critical role for FcgammaRIIB in up-regulation of Fas ligand induced by a microbial polysaccharide

scientific article published on 23 May 2011

A defect in ATP-citrate lyase links acetyl-CoA production, virulence factor elaboration and virulence in Cryptococcus neoformans

scientific article

Accelerated decay of C3b to iC3b when C3b is bound to the Cryptococcus neoformans capsule

scientific article published on October 1993

Activated neutrophils exhibit enhanced phagocytosis of Cryptococcus neoformans opsonized with normal human serum

scientific article published in October 1987

Activation and binding of C3 by Candida albicans.

scientific article published on August 1987

Activation and binding of opsonic fragments of C3 on encapsulated Cryptococcus neoformans by using an alternative complement pathway reconstituted from six isolated proteins

scientific article

Activation of C3 and binding to Aspergillus fumigatus conidia and hyphae

scientific article

Activation of the alternative complement pathway by fungal melanins

scientific article

Activation of the complement system by Cryptococcus neoformans leads to binding of iC3b to the yeast

scientific article published on April 1986

Activation of the complement system by pathogenic fungi

scientific article

Activation of the complement system by the capsule of Cryptococcus neoformans

scientific article

Acute lethal toxicity following passive immunization for treatment of murine cryptococcosis

scientific article published on May 1997

Adherence to and damage of endothelial cells by Cryptococcus neoformans in vitro: role of the capsule ⬇️

scientific article published on November 1, 1995

An immunohistochemical method that differentiates Cryptococcus neoformans varieties and serotypes in formalin-fixed paraffin-embedded tissues

scientific article published on December 2001

Antibody interactions with the capsule of Cryptococcus neoformans

scientific article

Antibody to Cryptococcus neoformans capsular glucuronoxylomannan promotes expression of interleukin-12Rbeta2 subunit on human T cells in vitro through effects mediated by antigen-presenting cells

scientific article published in June 2002

Antigenic and biological characteristics of mutant strains of Cryptococcus neoformans lacking capsular O acetylation or xylosyl side chains

scientific article

Antigenic structure of Cryptococcus neoformans capsular polysaccharides

scientific article published on January 1989

Antigenic variation within serotypes of Cryptococcus neoformans detected by monoclonal antibodies specific for the capsular polysaccharide

scientific article published on October 1989

Benzoquinone activation of Cryptococcus neoformans capsular polysaccharide for construction of an immunoaffinity column

scientific article published on 01 February 1988

Binding and internalization of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans, by murine peritoneal macrophages

scientific article

Binding of Cryptococcus neoformans to heterologously expressed human complement receptors

scientific article published on March 1997

Binding of cryptococcal polysaccharide to Cryptococcus neoformans ⬇️

scientific article published on March 1, 1984

Biological activities of naturally occurring antibodies reactive with Candida albicans mannan

scientific article

Biosensing with nanofluidic diodes

scientific article

Bivalency is required for anticapsular monoclonal antibodies to optimally suppress activation of the alternative complement pathway by the Cryptococcus neoformans capsule

scientific article

Brief Report: Geographical Variation in Prevalence of Cryptococcal Antigenemia Among HIV-Infected, Treatment-Naive Patients in Nigeria: A Multicenter Cross-Sectional Study

scientific article published on 03 May 2016

Capsular polysaccharide induction of apoptosis by intrinsic and extrinsic mechanisms.

scientific article

Capsular polysaccharide of Cryptococcus neoformans induces proinflammatory cytokine release by human neutrophils

scientific article published on August 1996

Capsular reactions of Cryptococcus neoformans with polyspecific and oligospecific polyclonal anticapsular antibodies

scientific article

Characteristics of Fc-independent human antimannan antibody-mediated alternative pathway initiation of C3 deposition to Candida albicans

scientific article

Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies.

scientific article

Chemotaxigenesis and activation of the alternative complement pathway by encapsulated and non-encapsulated Cryptococcus neoformans ⬇️

scientific article published on November 1, 1979

Complement is essential for protection by an IgM and an IgG3 monoclonal antibody against experimental, hematogenously disseminated candidiasis.

scientific article

Concomitant but not causal association between surface charge and inhibition of phagocytosis by cryptococcal polysaccharide.

scientific article

Conservation of Mannan Synthesis in Fungi of the Zygomycota and Ascomycota Reveals a Broad Diagnostic Target.

scientific article

Constant domains influence binding of mouse-human chimeric antibodies to the capsular polypeptide of Bacillus anthracis

scientific article published on 17 July 2013

Contrasting roles of mannan-specific monoclonal immunoglobulin M antibodies in the activation of classical and alternative pathways by Candida albicans.

scientific article

Contribution of antibody in normal human serum to early deposition of C3 onto encapsulated and nonencapsulated Cryptococcus neoformans ⬇️

scientific article published on March 1, 1992

Contribution of epitope specificity to the binding of monoclonal antibodies to the capsule of Cryptococcus neoformans and the soluble form of its major polysaccharide, glucuronoxylomannan

scientific article

CrAg lateral flow assay for cryptococcosis

scientific article published on 19 April 2012

Cryptococcus neoformans capsular glucuronoxylomannan induces expression of fas ligand in macrophages

scientific article

Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence

scientific article

Detection of Bacillus anthracis in animal tissues using InBios active anthrax detect rapid test lateral flow immunoassay

scientific article published on 28 March 2019

Differential localization of complement component 3 within the capsular matrix of Cryptococcus neoformans

scientific article

Dissociation of a hydrophobic surface from phagocytosis of encapsulated and non-encapsulated cryptococcus neoformans ⬇️

scientific article published on March 1, 1983

Distinct characteristics of initiation of the classical and alternative complement pathways by Candida albicans

scientific article published on August 1996

Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes

scientific article

Early events in initiation of alternative complement pathway activation by the capsule of Cryptococcus neoformans ⬇️

scientific article published on September 1, 1991

Effects of strain variation, serotype, and structural modification on kinetics for activation and binding of C3 to Cryptococcus neoformans.

scientific article published on July 1993

Efficacy of opsonic and nonopsonic serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibodies against intranasal challenge with Streptococcus pneumoniae in mice

scientific article published on 21 January 2009

Encapsulation of Cryptococcus neoformans with glucuronoxylomannan inhibits the antigen-presenting capacity of monocytes

scientific article published on February 1998

Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis

scientific article

Extracellular Deoxyribonuclease Production by Yeasts ⬇️

scientific article

Fc-dependent and Fc-independent opsonization of Cryptococcus neoformans by anticapsular monoclonal antibodies: importance of epitope specificity

scientific article

Fungal diagnostics

scientific article

Genetic and pathological characteristics of Cryptococcus gattii and Cryptococcus neoformans var. neoformans from meningoencephalitis in autochthonous goats and mouflons, Sardinia, Italy

scientific article published on 17 March 2015

Glucuronoxylomannan, a microbial compound, regulates expression of costimulatory molecules and production of cytokines in macrophages

scientific article

Glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans, inhibits the progression of group B streptococcal arthritis

scientific article

Human recombinant antimannan immunoglobulin G1 antibody confers resistance to hematogenously disseminated candidiasis in mice

scientific article

Identification of Burkholderia cepacia complex bacteria with a lipopolysaccharide-specific monoclonal antibody

scientific article

Identification of a monoclonal antibody from Peromyscus maniculatus (deer mouse) cytomegalovirus (PCMV) which binds to a protein with homology to the human CMV matrix protein HCMV pp71.

scientific article

Identification of circulating bacterial antigens by in vivo microbial antigen discovery

scientific article

IgG subclass and heavy chain domains contribute to binding and protection by mAbs to the poly γ-D-glutamic acid capsular antigen of Bacillus anthracis

scientific article

Immune Response to Cryptococcus neoformans Soluble Polysaccharide I. Serological Assay for Antigen and Antibody ⬇️

scientific article published on January 1, 1972

Immune response to Cryptococcus neoformans soluble polysaccharide: immunological unresponsiveness ⬇️

scientific article published on December 1, 1977

Immunoassay for Capsular Antigen of Bacillus anthracis Enables Rapid Diagnosis in a Rabbit Model of Inhalational Anthrax

scientific article published on 5 May 2015

Immunomodulation with CD40 stimulation and interleukin-2 protects mice from disseminated cryptococcosis

scientific article

In Vivo Microbial Antigen Discovery (InMAD) to identify diagnostic proteins and polysaccharides that are circulating during microbial infections

scientific article published on January 2013

In vivo complement activation and binding of C3 to encapsulated Cryptococcus neoformans ⬇️

scientific article published on September 1, 1992

In vivo fate and distribution of poly-gamma-D-glutamic acid, the capsular antigen from Bacillus anthracis

scientific article

Influence of IgG Subclass on Human Antimannan Antibody-Mediated Resistance to Hematogenously Disseminated Candidiasis in Mice

scientific article published on 16 November 2015

Influence of mannan and glucan on complement activation and C3 binding by Candida albicans

scientific article

Influence of opsonization conditions on C3 deposition and phagocyte binding of large- and small-capsule Cryptococcus neoformans cells.

scientific article

Inhibition of phagocytosis by cryptococcal polysaccharide: dissociation of the attachment and ingestion phases of phagocytosis ⬇️

scientific article published on July 1, 1976

Interdependency of interleukin-10 and interleukin-12 in regulation of T-cell differentiation and effector function of monocytes in response to stimulation with Cryptococcus neoformans

scientific article

Interleukin-12 counterbalances the deleterious effect of human immunodeficiency virus type 1 envelope glycoprotein gp120 on the immune response to Cryptococcus neoformans

scientific article published on 21 November 2000

Involvement of C3a and C5a in interleukin-8 secretion by human polymorphonuclear cells in response to capsular material of Cryptococcus neoformans

scientific article

Isolation and characterization of Cryptococcus neoformans spores reveal a critical role for capsule biosynthesis genes in spore biogenesis

scientific article published on 30 January 2009

Kinetic analysis of the amplification phase for activation and binding of C3 to encapsulated and nonencapsulated Cryptococcus neoformans ⬇️

scientific article published on August 1, 1992

Kinetics of lethal factor and poly-D-glutamic acid antigenemia during inhalation anthrax in rhesus macaques

scientific article

Large-scale evaluation of the immuno-mycologics lateral flow and enzyme-linked immunoassays for detection of cryptococcal antigen in serum and cerebrospinal fluid

scientific article published on 31 October 2012

Localization on encapsulated Cryptococcus neoformans of serum components opsonic for phagocytosis by macrophages and neutrophils ⬇️

scientific article published on February 1, 1984

Mannan-specific immunoglobulin G antibodies in normal human serum accelerate binding of C3 to Candida albicans via the alternative complement pathway.

scientific article

Mannan-specific immunoglobulin G antibodies in normal human serum mediate classical pathway initiation of C3 binding to Candida albicans ⬇️

scientific article published on September 1, 1997

Microbial immune suppression mediated by direct engagement of inhibitory Fc receptor

scientific article published on November 2006

Modulation of C5aR expression on human neutrophils by encapsulated and acapsular Cryptococcus neoformans

scientific article

Molecular and idiotypic analysis of antibodies to Cryptococcus neoformans glucuronoxylomannan.

scientific article published on September 1994

Molecular architecture of the Cryptococcus neoformans capsule

scientific article

Monoclonal antibodies reactive with immunorecessive epitopes of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans

scientific article published in September 2003

Monoclonal antibodies specific for immunorecessive epitopes of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans, reduce serotype bias in an immunoassay for cryptococcal antigen

scientific article

Non-encapsulated variant of Cryptococcus neoformans. II. Surface receptors for cryptococcal polysaccharide and their role in inhibition of phagocytosis by polysaccharide ⬇️

scientific article published on April 1, 1977

Nonencapsulated Variant of Cryptococcus neoformans I. Virulence Studies and Characterization of Soluble Polysaccharide.

scientific article

Occurrences, immunoglobulin classes, and biological activities of antibodies in normal human serum that are reactive with Cryptococcus neoformans glucuronoxylomannan

scientific article published on July 1994

Occurrences, specificities, and functions of ubiquitous antibodies in human serum that are reactive with the Cryptococcus neoformans cell wall

scientific article published on January 1994

Opsonization and phagocytosis of Cryptococcus neoformans.

scientific article published on January 1993

Opsonization of Cryptococcus neoformans by a family of isotype-switch variant antibodies specific for the capsular polysaccharide

scientific article published on June 1990

Opsonization of Cryptococcus neoformans by human immunoglobulin G: masking of immunoglobulin G by cryptococcal polysaccharide ⬇️

scientific article published on July 1, 1979

Opsonization of Cryptococcus neoformans by human immunoglobulin G: role of immunoglobulin G in phagocytosis by macrophages ⬇️

scientific article published on July 1, 1979

Opsonization of encapsulated Cryptococcus neoformans by specific anticapsular antibody.

scientific article

Passive immunization against Cryptococcus neoformans with an isotype-switch family of monoclonal antibodies reactive with cryptococcal polysaccharide

scientific article published on June 1990

Phagocytosis of Cryptococcus neoformans by normal and thioglycolate-activated macrophages ⬇️

scientific article published on September 1, 1978

Phenotypic heterogeneity in expression of epitopes in the Cryptococcus neoformans capsule

scientific article published on 02 September 2009

Point-of-Care Testing for Infectious Diseases: Past, Present, and Future

scientific article published on 24 May 2017

Polysaccharide specific monoclonal antibodies provide passive protection against intranasal challenge with Burkholderia pseudomallei

scientific article

Production and characterization of monoclonal antibodies specific for Cryptococcus neoformans capsular polysaccharide.

scientific article published on August 1987

Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule

scientific article

Protein-polysaccharide interactions. A monoclonal antibody specific for the capsular polysaccharide of Cryptococcus neoformans

scientific article published in January 1994

Rapid detection of the poly-gamma-D-glutamic acid capsular antigen of Bacillus anthracis by latex agglutination

scientific article published on 02 April 2009

Reactivity patterns and epitope specificities of anti-Cryptococcus neoformans monoclonal antibodies by enzyme-linked immunosorbent assay and dot enzyme assay.

scientific article published on February 1997

Recent advances in biology and immunology of Cryptococcus neoformans

scientific article published on January 1, 1992

Reply to Lee and Newton

scientific article published in 2012

Role of glucan and surface protein BAD1 in complement activation by Blastomyces dermatitidis yeast

scientific article

Role of the capsule in phagocytosis of Cryptococcus neoformans.

scientific article published on July 1988

Serological, electrophoretic, and biological properties of Cryptococcus neoformans antigens.

scientific article published on February 1988

Serotype sensitivity of a lateral flow immunoassay for cryptococcal antigen

scientific article published on 30 January 2013

Serotyping of Cryptococcus neoformans by dot enzyme assay.

scientific article published on February 1996

Specificity of the thioester-containing reactive site of human C3 and its significance to complement activation

scientific article published on September 1994

Stereo-selective binding of monoclonal antibodies to the poly-γ-D-glutamic acid capsular antigen of Bacillus anthracis

scientific article published on 17 April 2013

Strain variation in phagocytosis of Cryptococcus neoformans: dissociation of susceptibility to phagocytosis from activation and binding of opsonic fragments of C3

scientific article

Structure and biological activities of acapsular Cryptococcus neoformans 602 complemented with the CAP64 gene

scientific article published on May 1997

The capsule of Cryptococcus neoformans reduces T-lymphocyte proliferation by reducing phagocytosis, which can be restored with anticapsular antibody

scientific article

The road to toxin-targeted therapeutic antibodies

scientific article

Tracheal colonization factor A (TcfA) is a biomarker for rapid and specific detection of Bordetella pertussis

scientific article published on 14 September 2020

Virulence factors of Cryptococcus neoformans

scientific article published on August 1995

mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia

scholarly article

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