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List of works by Zachary T Schug

3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers

scientific article published on 26 November 2018

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

scientific article published on January 2017

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

scientific article

BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

scientific article published on 18 November 2020

Calcium-dependent conformational changes in inositol trisphosphate receptors.

scientific article

Cancer metabolism at a glance

scientific article published in September 2016

Cardiolipin acts as a mitochondrial signalling platform to launch apoptosis.

scientific article published on 18 May 2009

Changes in Aged Fibroblast Lipid Metabolism Induce Age-dependent Melanoma Cell Resistance to Targeted Therapy Via the Fatty Acid Transporter FATP2

scientific article published on 04 June 2020

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

scientific article published on 18 March 2020

Formaldehyde Detoxification Creates a New Wheel for the Folate-Driven One-Carbon "Bi"-cycle

scientific article

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.

scientific article

NAD+ metabolism governs the proinflammatory senescence-associated secretome

scientific article published on 18 February 2019

Polyunsaturated Fatty Acids from Astrocytes Activate PPARγ Signaling in Cancer Cells to Promote Brain Metastasis

scientific article published on 02 October 2019

Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection

scientific article

Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability

scientific article

Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma

scientific article published on 20 January 2022

Role of inositol 1,4,5-trisphosphate receptors in apoptosis in DT40 lymphocytes.

scientific article

Targeting ACSS2 with a transition state mimetic inhibits triple-negative breast cancer growth

scientific article published on 07 January 2021

Targeting cancer metabolism in the era of precision oncology

scientific article published in 2021

The Nurture of Tumors Can Drive Their Metabolic Phenotype

scientific article published on 01 March 2016

The Primary Effect on the Proteome of ARID1A-mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-transcriptional Level.

scientific article published on 21 September 2016

The metabolic fate of acetate in cancer

scientific article

The music of lipids: how lipid composition orchestrates cellular behaviour

scientific article

The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth.

scientific article published on 19 May 2016

The role of the S4-S5 linker and C-terminal tail in inositol 1,4,5-trisphosphate receptor function

scientific article published on 30 June 2006

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