List of works - Claire Coderch

A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis.

scientific article

Comparative binding energy (COMBINE) analysis supports a proposal for the binding mode of epothilones to β-tubulin

scientific article published on 16 March 2012

Comparative binding energy COMBINE analysis for understanding the binding determinants of type II dehydroquinase inhibitors.

scientific article published on March 2013

Design and synthesis of novel dual-target agents for HDAC1 and CK2 inhibition

scholarly article in RSC Advances, vol. 6 no. 71, 2016

Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

scientific article published on 01 January 2015

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

scientific article published on 28 November 2017

Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold

scientific article published on 17 August 2018

From a MMP2/CK2 multitarget approach to the identification of potent and selective MMP13 inhibitors

scientific article published on 01 January 2019

Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity

scientific article published on 20 April 2011

In silico identification and in vivo characterization of small molecule therapeutic hypothermia mimetics.

scientific article published on 31 October 2017

Insights into the Interaction of Discodermolide and Docetaxel with Tubulin. Mapping the Binding Sites of Microtubule-Stabilizing Agents by Using an Integrated NMR and Computational Approach ⬇️

scientific article published on May 13, 2011

Mechanistic Insight into the Catalytic Activity of ββα-Metallonucleases from Computer Simulations: Vibrio vulnificus Periplasmic Nuclease as a Test Case

article

Mechanistic insight into the reaction catalysed by bacterial type II dehydroquinases

scientific article published on 01 March 2014

Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches

scientific article published on 25 February 2014

New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1′ segment

scholarly article in RSC Advances, vol. 4 no. 34, 2014

One-pot synthesis of vinca alkaloids-phomopsin hybrids

scientific article

Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel.

scientific article

Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol.

scientific article

Synthesis, biological activity and structural study of new benzotriazole-based protein kinase CK2 inhibitors

scholarly article in RSC Advances, vol. 5 no. 89, 2015

List of works by Claire Coderch

A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis.

Comparative binding energy (COMBINE) analysis supports a proposal for the binding mode of epothilones to β-tubulin

Comparative binding energy COMBINE analysis for understanding the binding determinants of type II dehydroquinase inhibitors.

Design and synthesis of novel dual-target agents for HDAC1 and CK2 inhibition

Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders

Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold

From a MMP2/CK2 multitarget approach to the identification of potent and selective MMP13 inhibitors

Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity

In silico identification and in vivo characterization of small molecule therapeutic hypothermia mimetics.

Insights into the Interaction of Discodermolide and Docetaxel with Tubulin. Mapping the Binding Sites of Microtubule-Stabilizing Agents by Using an Integrated NMR and Computational Approach ⬇️

Mechanistic Insight into the Catalytic Activity of ββα-Metallonucleases from Computer Simulations: Vibrio vulnificus Periplasmic Nuclease as a Test Case

Mechanistic insight into the reaction catalysed by bacterial type II dehydroquinases

Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches

New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1′ segment

One-pot synthesis of vinca alkaloids-phomopsin hybrids

Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel.

Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol.

Synthesis, biological activity and structural study of new benzotriazole-based protein kinase CK2 inhibitors