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List of works by Simon L Goodman

A simple and rapid method for the reversible removal of lipids from a membrane-bound enzyme ⬇️

scientific article published on February 1, 1978

Atomic Basis for the Species-specific Inhibition of  V Integrins by Monoclonal Antibody 17E6 Is Revealed by the Crystal Structure of  V 3 Ectodomain-17E6 Fab Complex

scientific article

CYR61 and alphaVbeta5 integrin cooperate to promote invasion and metastasis of tumors growing in preirradiated stroma.

scientific article

Cell-cell interaction and polarity of epithelial cells: specific perturbation using a monoclonal antibody.

scientific article

Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome

scientific article published on 22 February 2016

Circulating and imaging markers for angiogenesis.

scientific article published on 17 October 2008

Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist.

scientific article

Dissecting the role of matrix metalloproteinases (MMP) and integrin alpha(v)beta3 in angiogenesis in vitro: absence of hemopexin C domain bioactivity, but membrane-Type 1-MMP and alpha(v)beta3 are critical.

scientific article

Distinctive role of integrin-mediated adhesion in TNF-induced PKB/Akt and NF-kappaB activation and endothelial cell survival.

scientific article published on 19 March 2007

Divalent cations and the relationship between alphaA and betaA domains in integrins.

scientific article

Immunohistochemical screening for beta6-integrin subunit expression in adenocarcinomas using a novel monoclonal antibody reveals strong up-regulation in pancreatic ductal adenocarcinomas in vivo and in vitro.

scientific article published on September 2004

Improving implant materials by coating with nonpeptidic, highly specific integrin ligands.

scientific article published in December 2004

Integrin control of the transforming growth factor-β pathway in glioblastoma.

scientific article published on 31 January 2013

Integrins and their ligands are expressed in non-small cell lung cancer but not correlated with parameters of disease progression

scientific article published on 26 November 2013

Integrins as Therapeutic Targets: Successes and Cancers.

scientific article published on 23 August 2017

Integrins as therapeutic targets.

scientific article published on 25 May 2012

Integrins in cell migration

scientific article published on 01 January 1999

Integrins αvβ3 and αvβ5 as prognostic, diagnostic, and therapeutic targets in gastric cancer

scientific article

Invasion patterns in brain metastases of solid cancers

scientific article published on 30 September 2013

Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy

scientific article published on 01 February 2006

Multimeric cyclic RGD peptides as potential tools for tumor targeting: solid-phase peptide synthesis and chemoselective oxime ligation

scientific article published in June 2003

Neovascular targeting with cyclic RGD peptide (cRGDf-ACHA) to enhance delivery of radioimmunotherapy

New insights into the structural basis of integrin activation.

scientific article

Ouabain binding to phospholipid-dependent adenosine triphosphatase ⬇️

scientific article published on February 1, 1978

Pharmacological inhibition of the vitronectin receptor abrogates PDGF-BB-induced hepatic stellate cell migration and activation in vitro

scientific article published on 12 December 2006

Piltdown wasn't cricket but does the hobbit ring true?

scientific article published in September 2006

Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectin

scientific article

Structure and mechanics of integrin-based cell adhesion.

scientific article published on 24 October 2007

The 3rd Antibody Validation meeting: Bath UK 20-21 September 2018

scientific article published on 31 December 2018

The Antibody Society's antibody validation webinar series

scientific article published on 01 January 2020

The path to VICTORy - a beginner's guide to success using commercial research antibodies

scientific article published on 15 May 2018

The αVβ3/αVβ5 integrin inhibitor cilengitide augments tumor response to melphalan isolated limb perfusion in a sarcoma model

scientific article published on 05 December 2012

Titanium implant materials with improved biocompatibility through coating with phosphonate-anchored cyclic RGD peptides.

scientific article

Validation and comparison of anti-αvβ3 and anti-αvβ5 rabbit monoclonal versus murine monoclonal antibodies in four different tumor entities

scientific article published on December 2013

alphav beta 3 and alphav beta 5 integrin antagonists inhibit angiogenesis in vitro.

scientific article

αvβ3, αvβ5 and αvβ6 integrins in brain metastases of lung cancer

scientific article

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