List of works - Alexander N Weber

1-ethyl-3-(6-methylphenanthridine-8-il) urea modulates TLR3/9 activation and induces selective pro-inflammatory cytokine expression in vitro.

scientific article

A Genetic Variation of Lipopolysaccharide Binding Protein Affects the Inflammatory Response and Is Associated with Improved Outcome during Sepsis

scientific article published in 2021

A Naturally Occurring Variant in Human TLR9, P99L, Is Associated with Loss of CpG Oligonucleotide Responsiveness ⬇️

scientific article published on September 14, 2010

Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival

scientific article

Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis.

scientific article published on 20 December 2013

Conserved mechanisms of signal transduction by Toll and Toll-like receptors

scientific article published on 01 January 2005

Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria.

scientific article published on 19 October 2010

Four N-linked glycosylation sites in human toll-like receptor 2 cooperate to direct efficient biosynthesis and secretion.

scientific article published on June 2004

Gadd45a is an RNA binding protein and is localized in nuclear speckles.

scientific article

Heterozygous carriage of a dysfunctional Toll-like receptor 9 allele affects CpG oligonucleotide responses in B cells.

scientific article

Ligand-receptor and receptor-receptor interactions act in concert to activate signaling in the Drosophila toll pathway.

scientific article

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

scientific article published on 08 January 2020

Neutrophils express distinct RNA receptors in a non-canonical way.

scientific article

Neutrophils: Between host defence, immune modulation, and tissue injury

scientific article

Oncogenic MYD88 mutations in lymphoma: novel insights and therapeutic possibilities

scientific article published on 11 September 2018

Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus

scientific article published on 8 October 2015

Recent insights into the regulatory networks of NLRP3 inflammasome activation

scientific article published on 03 December 2020

Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA

scientific article

Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling ⬇️

scientific article published on July 16, 2012

Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle.

scientific article

The Bruton tyrosine kinase inhibitor ibrutinib abrogates triggering receptor on myeloid cells 1-mediated neutrophil activation

scientific article published on 25 January 2017

The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold.

scientific article

The NLRP3 inflammasome and bruton's tyrosine kinase in platelets co-regulate platelet activation, aggregation, and in vitro thrombus formation.

scientific article

The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity

scientific article

The fungal ligand chitin directly binds TLR2 and triggers inflammation dependent on oligomer size

scientific article published on 18 October 2018

The role of FIBCD1 in response to Aspergillus fumigatus in lung epithelial cells

scientific article published in 2023

Toll and IMD pathways synergistically activate an innate immune response in Drosophila melanogaster

scientific article published on 16 April 2007

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes

scientific article published on 24 November 2009

Toll-like receptor genetic variants and colorectal cancer.

scientific article published on 10 January 2014

List of works by Alexander N Weber

1-ethyl-3-(6-methylphenanthridine-8-il) urea modulates TLR3/9 activation and induces selective pro-inflammatory cytokine expression in vitro.

A Genetic Variation of Lipopolysaccharide Binding Protein Affects the Inflammatory Response and Is Associated with Improved Outcome during Sepsis

A Naturally Occurring Variant in Human TLR9, P99L, Is Associated with Loss of CpG Oligonucleotide Responsiveness ⬇️

Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival

Cell death triggered by Yersinia enterocolitica identifies processing of the proinflammatory signal adapter MyD88 as a general event in the execution of apoptosis.

Conserved mechanisms of signal transduction by Toll and Toll-like receptors

Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria.

Four N-linked glycosylation sites in human toll-like receptor 2 cooperate to direct efficient biosynthesis and secretion.

Gadd45a is an RNA binding protein and is localized in nuclear speckles.

Heterozygous carriage of a dysfunctional Toll-like receptor 9 allele affects CpG oligonucleotide responses in B cells.

Ligand-receptor and receptor-receptor interactions act in concert to activate signaling in the Drosophila toll pathway.

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

Neutrophils express distinct RNA receptors in a non-canonical way.

Neutrophils: Between host defence, immune modulation, and tissue injury

Oncogenic MYD88 mutations in lymphoma: novel insights and therapeutic possibilities

Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus

Recent insights into the regulatory networks of NLRP3 inflammasome activation

Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA

Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling ⬇️

Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle.

The Bruton tyrosine kinase inhibitor ibrutinib abrogates triggering receptor on myeloid cells 1-mediated neutrophil activation

The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold.

The NLRP3 inflammasome and bruton's tyrosine kinase in platelets co-regulate platelet activation, aggregation, and in vitro thrombus formation.

The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity

The fungal ligand chitin directly binds TLR2 and triggers inflammation dependent on oligomer size

The role of FIBCD1 in response to Aspergillus fumigatus in lung epithelial cells

Toll and IMD pathways synergistically activate an innate immune response in Drosophila melanogaster

Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes

Toll-like receptor genetic variants and colorectal cancer.