List of works by Tom Hutchinson

A copepod life-cycle test and growth model for interpreting the effects of lindane.

scientific article published in March 2003

A microplate freshwater copepod bioassay for evaluating acute and chronic effects of chemicals.

scientific article published in June 2005

A review of the biology of European cockles (Cerastoderma spp.)

article

A review of the effects of bromate on aquatic organisms and toxicity of bromate to oyster (Crassostrea gigas) embryos.

scientific article published on December 1997

A strategy to reduce the numbers of fish used in acute ecotoxicity testing of pharmaceuticals.

scientific article published in December 2003

A strategy to reduce the use of fish in acute ecotoxicity testing of new chemical substances notified in the European Union

scientific article published on 01 July 2005

Acute and chronic effects of carrier solvents in aquatic organisms: a critical review.

scientific article

Advancing the 3Rs in regulatory ecotoxicology: A pragmatic cross-sector approach

scientific article published on 6 October 2015

An optimised experimental test procedure for measuring chemical effects on reproduction in the fathead minnow, Pimephales promelas

scientific article published on 18 November 2006

Analysis of the Ecetoc Aquatic Toxicity (EAT) database I — General introduction

Analysis of the ecetoc aquatic toxicity (EAT) database II — Comparison of acute to chronic ratios for various aquatic organisms and chemical substances

article

Analysis of the ecetoc aquatic toxicity (EAT) database III — Comparative toxicity of chemical substances to different life stages of aquatic organisms

article

Analysis of the ecetoc aquatic toxicity (EAT) database IV — Comparative toxicity of chemical substances to freshwater versus saltwater organisms

article

Assessing chronic toxicity of bisphenol A to larvae of the African clawed frog (Xenopus laevis) in a flow-through exposure system.

scientific article published in October 2003

Assessing the biological potency of binary mixtures of environmental estrogens using vitellogenin induction in juvenile rainbow trout (Oncorhynchus mykiss).

scientific article

Assessment of developmental effects, cytotoxicity and genotoxicity in the marine polychaete (Platynereis dumerilii) exposed to disinfected municipal sewage effluent.

scientific article published in March 1998

Assessment of putative endocrine disrupters in an in vivo crustacean assay and an in vitro insect assay.

scientific article published in September 2002

Associations between altered vitellogenin concentrations and adverse health effects in fathead minnow (Pimephales promelas).

scientific article published on 14 September 2007

Benefits of the maximum tolerated dose (MTD) and maximum tolerated concentration (MTC) concept in aquatic toxicology.

scientific article published on 24 November 2008

Challenging the requirement for chronic fish toxicity studies on formulated plant protection products.

scientific article published on 08 September 2010

Characterisation and expression of β1-, β2- and β3-adrenergic receptors in the fathead minnow (Pimephales promelas).

scientific article published on 31 July 2011

Chronic effects assessment and plasma concentrations of the beta-blocker propranolol in fathead minnows (Pimephales promelas).

scientific article published on 16 September 2009

Chronic toxicity of ibuprofen to Daphnia magna: Effects on life history traits and population dynamics

article

Cloning and gene expression of P450 17alpha-hydroxylase,17,20-lyase cDNA in the gonads and brain of the fathead minnow Pimephales promelas

scientific article published on February 2003

Comparative metabolism as a key driver of wildlife species sensitivity to human and veterinary pharmaceuticals

scientific article

Defining the chronic impacts of atenolol on embryo-larval development and reproduction in the fathead minnow (Pimephales promelas).

scientific article published on 3 December 2007

Derivation of an aquatic predicted no-effect concentration for the synthetic hormone, 17 alpha-ethinyl estradiol.

scientific article published in October 2008

Development and validation of a direct homologous quantitative sandwich ELISA for fathead minnow (Pimephales promelas) vitellogenin.

scientific article published on 27 April 2006

Development of adherence techniques for collecting kidney phagocytes from marine fish (Limanda limanda L.)

article

Development of an in vivo genotoxicity assay using the marine worm Platynereis dumerilii (Polychaeta: Nereidae)

article

Development of chronic tests for endocrine active chemicals. Part 1. An extended fish early-life stage test for oestrogenic active chemicals in the fathead minnow (Pimephales promelas).

scientific article published on 14 February 2006

Developmental changes of thyroid hormones in the fathead minnow, Pimephales promelas.

scientific article published on October 2004

Developmental toxicity of benzotriazole in the protochordate Ciona intestinalis (Chordata, Ascidiae).

scientific article published on 24 November 2009

EVALUATION OF THE REPRODUCTIVE EFFECTS OF TAMOXIFEN CITRATE IN PARTIAL AND FULL LIFE-CYCLE STUDIES USING FATHEAD MINNOWS (PIMEPHALES PROMELAS)

article

Ecological risk assessment and testing for endocrine disruption in the aquatic environment.

scientific article

Editorial

Effect of in vivo cadmium exposure on the respiratory burst of Marine Fish (Limanda limanda L.) phagocytes

article published in 1996

Effects of ammonium perchlorate on thyroid function in developing fathead minnows, Pimephales promelas.

scientific article

Effects of human pharmaceuticals on aquatic life: next steps.

scientific article

Effects on feeding rate and biomarker responses of marine mussels experimentally exposed to propranolol and acetaminophen.

scientific article published on 18 October 2009

Endocrine disruption in wildlife: identification and ecological relevance.

scientific article published in August 1999

Evaluation of non-specific immune functions in dab, Limanda limanda L., following short-term exposure to sediments contaminated with polyaromatic hydrocarbons and/or polychlorinated biphenyls.

scientific article published in April 2003

Evaluation of the genotoxicity of municipal sewage effluent using the marine worm Platynereis dumerilii (Polychaeta: Nereidae).

scientific article published in July 1997

Exposure to exogenous 17beta-oestradiol disrupts p450aromB mRNA expression in the brain and gonad of adult fathead minnows (Pimephales promelas).

scientific article published in October 2002

Expression of target and reference genes in Daphnia magna exposed to ibuprofen

scientific article

Extending the environmental risk assessment for oseltamivir (Tamiflu) under pandemic use conditions to the coastal marine compartment.

scientific article

Formation of micronuclei in erythrocytes of the fathead minnow (Pimephales promelas) after acute treatment with mitomycin C or cyclophosphamide

article

I.1 Evaluation of immunological methods to monitor environmental stress in marine flatfish

scholarly article published January 1994 in Developmental and Comparative Immunology

Immunological function in marine invertebrates: responses to environmental perturbation.

scientific article published on 02 April 2011

Impacts of climate change on indirect human exposure to pathogens and chemicals from agriculture

scientific article

In vivo and in vitro liver and gill EROD activity in rainbow trout (Oncorhynchus mykiss) exposed to the beta-blocker propranolol.

scientific article

Influence of a collapsed coastal landfill on metal levels in sediments and biota--a portent for the future?

scientific article

Interference with xenobiotic metabolic activity by the commonly used vehicle solvents dimethylsulfoxide and methanol in zebrafish (Danio rerio) larvae but not Daphnia magna

scientific article

Joint effects of density and a growth inhibitor on the life history and population growth rate of the midge Chironomus riparius.

scientific article published in May 2005

Juvenile king scallop, Pecten maximus, is potentially tolerant to low levels of ocean acidification when food is unrestricted.

scientific article

Linking genotoxic responses with cytotoxic and behavioural or physiological consequences: differential sensitivity of echinoderms (Asterias rubens) and marine molluscs (Mytilus edulis).

scientific article published on 10 June 2009

Linking molecular and population stress responses in Daphnia magna exposed to cadmium.

scientific article published in March 2008

Localization of a vertebrate telomeric sequence in the chromosomes of two marine worms (phylum Annelida: class polychaeta)

scientific article published on 01 December 1995

Meeting report: risk assessment of tamiflu use under pandemic conditions.

scientific article

Metabolism of ibuprofen in zebrafish larvae

scientific article published on 17 May 2012

Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow (Pimephales promelas).

scientific article published in May 2002

Pharmaceuticals in the Marine Environment

scholarly article

Population growth rate and carrying capacity for springtails Folsomia candida exposed to ivermectin

scientific article published on April 2006

Proteomic analysis of phospholipidosis in citalopram treated U937 cells--support for the cholesterol biosynthesis hypothesis.

scientific article

Pyrosequencing of Mytilus galloprovincialis cDNAs: tissue-specific expression patterns

scientific article

Reproductive and developmental effects of endocrine disrupters in invertebrates: in vitro and in vivo approaches

scientific article

Small-scale detritus-invertebrate interactions: influence of detrital biofilm composition on development and reproduction in a meiofaunal copepod

article

Sources, impacts and trends of pharmaceuticals in the marine and coastal environment

scientific article

Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna

scientific article published on 21 February 2008

The EU-project ERAPharm - Incentives for the further development of guidance documents? (4 pages)

article

The assessment of industrial effluent toxicity using aquatic microorganisms, invertebrates and fish

article

The chromosomes Of Platynereis dumerilii (Polychaeta: Nereidae)

scholarly article in Journal of the Marine Biological Association of the United Kingdom, vol. 75 no. 3, August 1995

The ecological niche of Daphnia magna characterized using population growth rate.

scientific article

The effects of methimazole on development of the fathead minnow, Pimephales promelas, from embryo to adult.

scientific article published on 13 July 2006

The impact of oestrogenic and androgenic contamination on marine organisms in the United Kingdom--summary of the EDMAR programme. Endocrine Disruption in the Marine Environment

scientific article published in September 2002

The polychaete Platynereis dumerilii (Audouin and Milne-Edwards): a new species for assessing the hazardous potential of chemicals in the marine environment.

scientific article published on August 1995

The use of sheepshead minnow (Cyprinodon variegatus) and a benthic copepod (Tisbe battagliai) in short-term tests for estimating the chronic toxicity of industrial effluents

article

Toxicity of cadmium, hexavalent chromium and copper to marine fish larvae (Cyprinodon variegatus) and copepods (Tisbe battagliai)

article

Uptake of propranolol, a cardiovascular pharmaceutical, from water into fish plasma and its effects on growth and organ biometry.

scientific article

Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances.

scientific article published in February 2002

Validation of the use of zebrafish larvae in visual safety assessment.

scientific article published on 2 May 2008

Window of sensitivity for the estrogenic effects of ethinylestradiol in early life-stages of fathead minnow, Pimephales promelas

scientific article