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List of works by Ali G Turhan

A mesenchymal glioma stem cell profile is related to clinical outcome

scientific article published on 17 March 2014

AHI-1 interacts with BCR-ABL and modulates BCR-ABL transforming activity and imatinib response of CML stem/progenitor cells

scientific journal article

Alteration Analysis of Bone Marrow Mesenchymal Stromal Cells from De Novo Acute Myeloid Leukemia Patients at Diagnosis

scientific article published on 10 April 2017

Altered IFNgamma signaling and preserved susceptibility to activated natural killer cell-mediated lysis of BCR/ABL targets.

scientific article

Amniotic fluid-derived mesenchymal stem cells prevent fibrosis and preserve renal function in a preclinical porcine model of kidney transplantation.

scientific article

Aryl hydrocarbon receptor (AHR) is a novel druggable pathway controlling malignant progenitor proliferation in chronic myeloid leukemia (CML)

scientific article published in PLoS ONE

BCR-ABL Fails to Inhibit Apoptosis in U937 Myelomonocytic Cells Expressing a Carboxyl-Terminal Truncated Stat5 ⬇️

scientific article published on July 1, 2001

BCR-ABL activates STAT3 via JAK and MEK pathways in human cells

scientific article published on 01 July 2006

BCR-ABL and constitutively active erythropoietin receptor (cEpoR) activate distinct mechanisms for growth factor-independence and inhibition of apoptosis in Ba/F3 cell line.

scientific article

BCR-ABL delays apoptosis upstream of procaspase-3 activation

scientific article published on 01 April 1998

BCR-ABL does not prevent apoptotic death induced by human natural killer or lymphokine-activated killer cells.

scientific article published on February 1996

BCR-ABL expression in leukemic progenitors and primitive stem cells of patients with chronic myeloid leukemia.

scientific article

BCR-ABL-induced deregulation of the IL-33/ST2 pathway in CD34+ progenitors from chronic myeloid leukemia patients

scientific article published on 27 March 2014

BCR/ABL promotes dendritic cell-mediated natural killer cell activation

scientific article published in July 2005

Biological effects induced by variable levels of BCR-ABL protein in the pluripotent hematopoietic cell line UT-7.

scientific article

Biological effects of T315I-mutated BCR-ABL in an embryonic stem cell-derived hematopoiesis model.

scientific article

Bone marrow mesenchymal stromal cell (MSC) gene profiling in chronic myeloid leukemia (CML) patients at diagnosis and in deep molecular response induced by tyrosine kinase inhibitors (TKIs).

scientific article published on 26 July 2017

Carcinoma cell leukemia

scientific article published on 01 September 1996

Cerebro-retinal microangiopathy with calcifications and cysts due to recessive mutations in the CTC1 gene

scientific article published on 2 April 2015

Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy.

scientific article published on September 2011

Chronic myeloid leukemia stem cells: cross-talk with the niche

scientific article

Clonal hematopoiesis demonstrated by X-linked DNA polymorphisms after allogeneic bone marrow transplantation

scientific article published on 01 June 1989

Comprehensive characterization of a novel intronic pseudo-exon inserted within an e14/a2 BCR-ABL rearrangement in a patient with chronic myeloid leukemia

scientific article

Constitutive and specific activation of STAT3 by BCR-ABL in embryonic stem cells.

scientific article

Corrigendum: Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells

scientific article

Cryptic del(13q14.2) and physiological deletions of immunoglobulin genes detected by high-resolution array comparative genomic hybridization in a patient with indolent chronic lymphocytic leukemia

scientific article published on 01 July 2007

Detection of breakpoint cluster region- negative and nonclonal hematopoiesis in vitro and in vivo after transplantation of cells selected in cultures of chronic myeloid leukemia marrow

scientific article published on 01 December 1990

Detection of clonal CD34+19+ progenitors in bone marrow of BCL2-IgH-positive follicular lymphoma patients

scientific article published on 01 December 1995

Differential contributions of STAT5A and STAT5B to stress protection and tyrosine kinase inhibitor resistance of chronic myeloid leukemia stem/progenitor cells

scientific article

Direct and rapid identification of T315I-Mutated BCR-ABL expressing leukemic cells using infrared microspectroscopy

scientific article published on 26 July 2018

Drug reaction with eosinophilia and systemic symptoms (DRESS) induced by imatinib in chronic myeloid leukemia

scientific article published on 07 July 2016

Duplication of the Ph-chromosome as a possible mechanism of resistance to imatinib mesylate in patients with chronic myelogenous leukemia.

scientific article

EGR1 dysregulation defines an inflammatory and leukemic program in cell trajectory of human-aged hematopoietic stem cells (HSC)

scientific article published on 22 July 2021

Efficient ex vivo expansion of NOD/SCID-repopulating cells with lympho-myeloid potential in hematopoietic grafts of children with solid tumors

scientific article published on 01 January 2001

Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding

scientific article published on 05 June 2020

Evaluation of beta-catenin activating mutations in chronic myeloid leukemia

scientific article published on 30 October 2007

Evaluation of hematopoietic potential generated by transplantation of muscle-derived stem cells in mice.

scientific article

Evidence for BCR‐ABL‐dependent dysfunctions of iNKT cells from chronic myeloid leukemia patients ⬇️

scientific article published on July 1, 2012

Experimental and integrative analyses identify an ETS1 network downstream BCR-ABL in chronic myeloid leukemia (CML).

scientific article published on 4 May 2018

Extensive analysis of the T315I substitution and detection of additional ABL mutations in progenitors and primitive stem cell compartment in a patient with tyrosine kinase inhibitor-resistant chronic myeloid leukemia ⬇️

scientific article published on October 7, 2010

Generation of an induced pluripotent stem cell (iPSC) line from a patient with maturity-onset diabetes of the young type 13 (MODY13) with a the potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) mutation.

scientific article published on 25 July 2017

Generation of an induced pluripotent stem cell (iPSC) line from a patient with maturity-onset diabetes of the young type 3 (MODY3) carrying a hepatocyte nuclear factor 1-alpha (HNF1A) mutation.

scientific article published on 7 March 2018

Generation of an induced pluripotent stem cell line from a patient with chronic myeloid leukemia (CML) resistant to targeted therapies.

scientific article published on 04 August 2016

Generation of an induced pluripotent stem cell line from a patient with hereditary multiple endocrine neoplasia 2A (MEN2A) syndrome with RET mutation

scientific article published on 27 June 2016

Generation of an induced pluripotent stem cell line from a patient with hereditary multiple endocrine neoplasia 2B (MEN2B) syndrome with "highest risk" RET mutation.

scientific article published on 22 July 2017

Generation of induced pluripotent stem cell (iPSC) line from a patient with triple negative breast cancer with hereditary exon 17 deletion of BRCA1 gene.

scientific article

Generation of multipotent early lymphoid progenitors from human embryonic stem cells.

scientific article

Global MicroRNA Profiling Uncovers miR-206 as a Negative Regulator of Hematopoietic Commitment in Human Pluripotent Stem Cells ⬇️

scientific article published on 08 April 2019

Haemophagocytic histiocyte in a peripheral blood film.

scientific article

Hematologic and immunologic changes in hairy cell leukemia patients treated with alpha interferon

scientific article published on 01 October 1988

High level of glutathione-S-transferase pi expression in mantle cell lymphomas.

scientific article

Highly purified primitive hematopoietic stem cells are PML-RARA negative and generate nonclonal progenitors in acute promyelocytic leukemia.

scientific article published in April 1995

Hodgkin's disease primarily involving the oropharynx: case report and review of the literature.

scientific article

Identification of spectral modifications occurring during reprogramming of somatic cells

scientific article

Imatinib mesylate: a major breakthrough in the treatment of chronic myelogenous leukemia

scientific article published in June 2003

In vitro culture and phenotypic and molecular characterization of gastric stem cells from human stomach

scientific article published on 4 September 2016

Ketoconazole versus nystatin as prophylaxis against fungal infection for lymphoma patients receiving chemotherapy

scientific article published on 01 August 1987

Leukemic stem cell persistence in chronic myeloid leukemia patients in deep molecular response induced by tyrosine kinase inhibitors and the impact of therapy discontinuation

scientific article published on 5 May 2016

Leukemic stem cell persistence in chronic myeloid leukemia patients with sustained undetectable molecular residual disease ⬇️

scientific article published on July 25, 2011

Leukemic target susceptibility to natural killer cytotoxicity: relationship with BCR-ABL expression

scientific article published on March 2002

Long-term follow-up of subtotal splenectomy for hereditary spherocytosis: a single-center study

scientific article published on 15 January 2016

Loss of major molecular response as a trigger for restarting tyrosine kinase inhibitor therapy in patients with chronic-phase chronic myelogenous leukemia who have stopped imatinib after durable undetectable disease

scientific article

Malignant Germ Cell–Like Tumors, Expressing Ki-1 Antigen (CD30), Are Revealed during in Vivo Differentiation of Partially Reprogrammed Human-Induced Pluripotent Stem Cells ⬇️

scientific article published on March 13, 2012

Mesenchymal cells generated from patients with myelodysplastic syndromes are devoid of chromosomal clonal markers and support short- and long-term hematopoiesis in vitro.

scientific article

Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia

scientific article

Modeling the influence of stromal microenvironment in the selection of ENU-induced BCR-ABL1 mutants by tyrosine kinase inhibitors.

scientific article published on 30 January 2014

Molecular analysis of clonality in Kaposi's sarcoma.

scientific article published on August 1997

Molecular investigation of adequate sources of mesenchymal stem cells for cell therapy of COVID-19-associated organ failure

scientific article published on 25 November 2020

Molecular pathophysiology of chronic myelogenous leukemia

scientific article published on 01 October 1998

Morphological analysis of human induced pluripotent stem cells during induced differentiation and reverse programming

scientific article

Multiple molecular mechanisms contribute to radiation sensitivity in mantle cell lymphoma.

scientific article published in September 2003

NK cells: a major role in the antitumoral immunomodulation in CML

scientific article published on 01 June 2018

Neutrophil gelatinase-associated lipocalin expression in chronic myeloid leukemia

scientific article published on 01 May 2008

Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells

scientific article published on June 2016

O6-Methylguanine-Methyltransferase (MGMT) Promoter Methylation Status in Glioma Stem-Like Cells is Correlated to Temozolomide Sensitivity Under Differentiation-Promoting Conditions ⬇️

scientific article published on June 7, 2012

Osteopontin is upregulated by BCR-ABL

scientific article published on 01 August 2005

Plasticity of adult stem cells

scientific article published in June 2003

Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate

scientific article

Quantitative and qualitative in vitro analysis of the stem cell potential of hematopoietic cells purified from murine skeletal muscle

scientific article published on 01 September 2007

Quantitative monitoring of the T315I mutation in patients with chronic myeloid leukemia (CML).

scientific article

Quantitative non-radioactive clonality analysis of human leukemic cells and progenitors using the human androgen receptor (AR) gene

scientific article published on 01 September 1995

Reply to J. Richter et al.

scientific article published on 28 July 2014

Reversible lymph node follicular hyperplasia associated with dasatinib treatment of chronic myeloid leukemia in chronic phase

scientific article published in October 2013

Reversible skin telangiectasia induced by imatinib mesylate in chronic myeloid leukemia.

scientific article

Reversing clonality in leukemia.

scientific article published on July 1991

STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: a potential for targeted therapy?

scientific article published in February 2011

STAT5 as a CML target: STATinib therapies?

scientific article published on 01 March 2011

Sequential emergence of ABL-kinase mutations with loss of unmutated BCR-ABL allele during targeted therapies of CML

scientific article published on 01 September 2006

Success of interferon α therapy in a patient with hepatitis C virus-negative splenic marginal zone lymphoma associated with polycythemia vera

scientific article published on 2 February 2015

Superoxide dismutase 2 (SOD2) contributes to genetic stability of native and T315I-mutated BCR-ABL expressing leukemic cells.

scientific article published on 14 March 2018

Targeting BCR-ABL+ stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex

scientific article published on 25 May 2017

Targeting primitive chronic myeloid leukemia cells by effective inhibition of a new AHI-1-BCR-ABL-JAK2 complex

scientific article published on 27 February 2013

The Durable Clearance of the T315I BCR-ABL Mutated Clone in Chronic Phase Chronic Myelogenous Leukemia Patients on Omacetaxine Allows Tyrosine Kinase Inhibitor Rechallenge ⬇️

scientific article published on October 1, 2010

The HOXB4 homeoprotein promotes the ex vivo enrichment of functional human embryonic stem cell-derived NK cells

scientific article

The decreased susceptibility of Bcr/Abl targets to NK cell-mediated lysis in response to imatinib mesylate involves modulation of NKG2D ligands, GM1 expression, and synapse formation

scientific article published on January 2006

The downregulation of BAP1 expression by BCR-ABL reduces the stability of BRCA1 in chronic myeloid leukemia.

scientific article

The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways.

scientific article

Toxicity and phototoxicity of Hypocrellin A on malignant human cell lines, evidence of a synergistic action of photodynamic therapy with Imatinib mesylate.

scientific article published on 6 March 2010

Transcriptional landscape of a RETC634Y-mutated iPSC and its CRISPR-corrected isogenic control reveals the putative role of EGR1 transcriptional program in the development of multiple endocrine neoplasia type 2A-associated cancers

scientific article published on 23 November 2017

Tyrosine kinase inhibitor AG1024 exerts antileukaemic effects on STI571-resistant Bcr-Abl expressing cells and decreases AKT phosphorylation.

scientific article published on November 2004

Tyrosine phosphorylation of SHIP promotes its proteasomal degradation.

scientific article published on 18 March 2010

Unfractionated peripheral blood stem cell autografts and CD(34+)-enriched autografts have similar long-term culture initiating capacity in multiple myeloma

scientific article published on 01 November 1999

Unique association of systemic mastocytosis and myeloid/lymphoid neoplasm in blast crisis with abnormality of FGFR1 gene.

scientific article published on 24 October 2011

Whole-genome analysis reveals unexpected dynamics of mutant subclone development in a patient with JAK2-V617F-positive chronic myeloid leukemia.

scientific article published on 7 June 2017

[Complications caused by the sudden stopping of antihypertensive drugs (except beta-blockers)]

scientific article published on 01 July 1984

[Gene transfer in hematopoietic cells. A major therapeutic tool for the future]

scientific article published on 01 January 1994

[Small-cell anaplastic bronchopulmonary cancers. Prognostic and therapeutic review apropos 49 cases]

scientific article published on 01 January 1983

[Voluntary poisoning with captopril]

scientific article published on 01 December 1984

iPSC-Derived Embryoid Bodies as Models of c-Met-Mutated Hereditary Papillary Renal Cell Carcinoma

scientific article published on 30 September 2019

p210BCR-ABL inhibits SDF-1 chemotactic response via alteration of CXCR4 signaling and down-regulation of CXCR4 expression

scientific article

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