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List of works by Miguel Manzanares

A functional survey of the enhancer activity of conserved non-coding sequences from vertebrate Iroquois cluster gene deserts.

scientific article published on 15 July 2005

A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system.

scientific article published on 24 June 2014

Active DNA demethylation at enhancers during the vertebrate phylotypic period

scientific article published on 29 February 2016

Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H.

scientific article

An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms

scientific article published on 30 August 2017

An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo

scientific journal article

An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation.

scientific article published in January 2011

Biological potential of a functional human SNAIL retrogene.

scientific article published on 31 July 2002

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.

scientific article published on 28 August 2017

Comparison of extraembryonic expression of Eomes and Cdx2 in pregastrulation chick and mouse embryo unveils regulatory changes along evolution.

scientific article published in February 2010

Conserved and distinct roles of kreisler in regulation of the paralogous Hoxa3 and Hoxb3 genes.

scientific article

Development: Hippo signalling turns the embryo inside out.

scientific article published in July 2013

Developmental biology. Raising the roof.

scientific article published in February 2000

Dorsal patterning defects in the hindbrain, roof plate and skeleton in the dreher (dr(J)) mouse mutant.

scientific article published in June 2000

Functional genomics of cardiovascular development and disease

scientific article published in January 2014

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes.

scientific article

Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.

scientific article

Germ cell restricted expression of chick Nanog.

scientific article published in October 2006

Krox20 and kreisler co-operate in the transcriptional control of segmental expression of Hoxb3 in the developing hindbrain.

scientific article

Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia.

scientific article

Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP.

scientific article published on 17 April 2015

MiRNA-mediated regulation of cell signaling and homeostasis in the early mouse embryo.

scientific article published on 15 February 2011

MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM.

scientific article

Modularity and reshuffling of Snail and Slug expression during vertebrate evolution.

scientific article

Nanog regulates Pou3f1 expression at the exit from pluripotency during gastrulation

scientific article published on 02 December 2019

Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst

scientific article

Our First Choice: Cellular and Genetic Underpinnings of Trophectoderm Identity and Differentiation in the Mammalian Embryo

scientific article published in January 2018

Patterning the ascidian nervous system: structure, expression and transgenic analysis of the CiHox3 gene.

scientific article published in November 1999

Pluripotency and lineages in the mammalian blastocyst: an evolutionary view.

scientific article published in June 2011

Reprogramming in vivo produces teratomas and iPS cells with totipotency features.

scientific article

Requirement for downregulation of kreisler during late patterning of the hindbrain.

scientific article published in March 2002

Segmental regulation of Hoxb-3 by kreisler.

scientific article published in May 1997

Segmentation in the crustacean Artemia: engrailed staining studied with an antibody raised against the Artemia protein

scientific article

Selective maintenance of Drosophila tandemly arranged duplicated genes during evolution

scientific article published on 16 December 2008

Signaling pathways in mammalian preimplantation development: Linking cellular phenotypes to lineage decisions.

scientific article published on 18 November 2016

Snail3 orthologues in vertebrates: divergent members of the Snail zinc-finger gene family.

scientific article published on 4 December 2003

The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation.

scientific article published on September 1996

The increasing complexity of the Snail gene superfamily in metazoan evolution.

scientific article published in April 2001

The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates

scientific article published on 27 February 2019

Transitions in cell potency during early mouse development are driven by Notch

article

Transposon tools for recombinant DNA manipulation: characterization of transcriptional regulators from yeast, Xenopus, and mouse.

scientific article published on April 1996

Understanding the regulatory genome.

scientific article published on January 2009

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