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List of works by Paul S. Brookes

A cell-based phenotypic assay to identify cardioprotective agents

scientific article

A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel

scientific article

Accumulation of Succinate in Cardiac Ischemia Primarily Occurs via Canonical Krebs Cycle Activity.

scientific article

Cardioprotection and mitochondrial S-nitrosation: effects of S-nitroso-2-mercaptopropionyl glycine (SNO-MPG) in cardiac ischemia-reperfusion injury

scientific article

Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I.

scientific article

Cardioprotection by metabolic shut-down and gradual wake-up

scientific article published on 10 March 2009

Cyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging Bone

scientific article

Different mechanisms of mitochondrial proton leak in ischaemia/reperfusion injury and preconditioning: implications for pathology and cardioprotection

scientific article published on May 2006

Direct evidence for S-nitrosation of mitochondrial complex I.

scientific article published in March 2006

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

In vivo cardioprotection by S-nitroso-2-mercaptopropionyl glycine

scientific article published on 03 February 2009

Internet publicity of data problems in the bioscience literature correlates with enhanced corrective action

scientific article

Intra-myocyte ion homeostasis during ischemia-reperfusion injury: effects of pharmacologic preconditioning and controlled reperfusion

scientific article published in October 2003

Ischemic preconditioning: the role of mitochondria and aging

scientific article published on 10 November 2011

Kir6.2 is not the mitochondrial KATP channel but is required for cardioprotection by ischemic preconditioning

scientific article published on 12 April 2013

Krebs cycle metabolites and preferential succinate oxidation following neonatal hypoxic-ischemic brain injury in mice

scientific article

Lysine deacetylation in ischaemic preconditioning: the role of SIRT1

scientific article

Metabolism: A Direct Link Between Cardiac Structure and Function

scientific article published in November 2017

Metabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation

scientific article

Methods for measuring the regulation of respiration by nitric oxide

scientific article published on January 2007

Mitochondria as a drug target in ischemic heart disease and cardiomyopathy

scientific article

Mitochondria as a target for the cardioprotective effects of nitric oxide in ischemia-reperfusion injury

scientific article published on March 2008

Mitochondrial H(+) leak and ROS generation: an odd couple

scientific article

Mitochondrial function in response to cardiac ischemia-reperfusion after oral treatment with quercetin

scientific article published in June 2002

Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: implications for cardioprotection

scientific article published on 02 December 2008

Mitochondrially targeted nitro-linoleate: a new tool for the study of cardioprotection

scientific article published on April 2014

Modulation of mitochondrial adenosine triphosphate-sensitive potassium channels and sodium-hydrogen exchange provide additive protection from severe ischemia-reperfusion injury

scientific article published in April 2003

NDUFS4: creation of a mouse model mimicking a Complex I disorder

scientific article published on 11 February 2009

Nitroalkenes confer acute cardioprotection via adenine nucleotide translocase 1.

scientific article

Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions

scientific article published on 14 April 2009

Redox regulation of the mitochondrial K(ATP) channel in cardioprotection

scientific article

Reversible inhibition of cytochrome c oxidase by peroxynitrite proceeds through ascorbate-dependent generation of nitric oxide

scientific article published on 12 May 2003

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

scientific article

SIRT1-mediated acute cardioprotection

scientific article

SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts

scientific article

SLO-2 is cytoprotective and contributes to mitochondrial potassium transport

scientific article

The C. elegans mitochondrial K+(ATP) channel: a potential target for preconditioning

scientific article published on 20 September 2008

The RSK Inhibitor BIX02565 Limits Cardiac Ischemia/Reperfusion Injury

scientific article published on 30 June 2015

The Slo(w) path to identifying the mitochondrial channels responsible for ischemic protection

scientific article

The cardioprotective compound cloxyquin uncouples mitochondria and induces autophagy

scientific article published on 30 October 2015

The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels

scientific article published on 26 February 2009

The coordinated increased expression of biliverdin reductase and heme oxygenase-2 promotes cardiomyocyte survival: a reductase-based peptide counters β-adrenergic receptor ligand-mediated cardiac dysfunction

scientific article

The endogenous mitochondrial complex II inhibitor malonate regulates mitochondrial ATP-sensitive potassium channels: implications for ischemic preconditioning

scientific article published on 8 April 2008

The mitochondrial complex II and ATP-sensitive potassium channel interaction: quantitation of the channel in heart mitochondria ⬇️

scientific article published on November 19, 2010

p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: a pathogenic mechanism for ischemia-reperfusion injury

scientific article

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