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List of works by Caroline Lee

42 Retroviral transfer of human MDR1 gene into human T lymphocytes

scientific article published on January 1, 1998

A non-synonymous single nucleotide polymorphism in an OPRM1 splice variant is associated with fentanyl-induced emesis in women undergoing minor gynaecological surgery

scientific article

A unique role for p53 in the regulation of M2 macrophage polarization

scientific article

Advances in genomic hepatocellular carcinoma research

scientific article published on 01 November 2018

Altered Binding Site Selection of p53 Transcription Cassettes by Hepatitis B Virus X Protein

scientific article published on November 12, 2012

An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics.

scientific article published on 31 May 2011

Analysis of MDR1 haplotypes in Parkinson's disease in a white population.

scientific article published in December 2004

Application of antibody-conjugated gold nanoparticles for optical molecular imaging of epithelial carcinoma cells

Architecture of polymorphisms in the human genome reveals functionally important and positively selected variants in immune response and drug transporter genes

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Architecture of population-differentiated polymorphisms in the human genome

scientific article published on 17 October 2019

Circulating microRNAs as Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma

scientific article published on 18 July 2019

Comprehensive analysis of transcriptome profiles in hepatocellular carcinoma

scientific article published on 20 August 2019

Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma

scientific article

DNA methylation: potential biomarker in Hepatocellular Carcinoma.

scientific article

Deep sequencing of the hepatitis B virus in hepatocellular carcinoma patients reveals enriched integration events, structural alterations and sequence variations

scientific article published on December 30, 2012

Defining the Performance Parameters of a Rapid Screening Tool for FMR1 CGG-Repeat Expansions Based on Direct Triplet-Primed PCR and Melt Curve Analysis

scientific article published on 30 June 2016

Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways

scientific article published on 28 January 2016

Dinucleotide repeats negatively modulate the promoter activity of Cyr61 and is unstable in hepatocellular carcinoma patients.

scientific article

Disruption of FAT10-MAD2 binding inhibits tumor progression.

scientific article

Efficient Long-Term Coexpression of a Hammerhead Ribozyme Targeted to the U5 Region of HIV-1 LTR by Linkage to the Multidrug-Resistance Gene

scientific article published on October 1, 1997

Efficient and highly sensitive screen for myotonic dystrophy type 1 using a one-step triplet-primed PCR and melting curve assay

scientific article

Enhanced Detection and Sizing of the HTT CAG Repeat Expansion in Huntington Disease Using an Improved Triplet-Primed PCR Assay

scientific article published on 21 May 2016

Exploiting internal ribosome entry sites in gene therapy vector design.

scientific article

FAT10, a gene up-regulated in various cancers, is cell-cycle regulated.

scientific article

FAT10, an ubiquitin-like protein, confers malignant properties in non-tumorigenic and tumorigenic cells.

scientific article published on 9 December 2013

FMR1 CGG repeat patterns and flanking haplotypes in three Asian populations and their relationship with repeat instability.

scientific article published in November 2006

Fetal polymorphisms at the ABCB1-transporter gene locus are associated with susceptibility to non-syndromic oral cleft malformations.

scientific article published on 27 February 2013

Giant hepatocellular adenoma presenting with chronic iron deficiency anemia.

scientific article published on 30 June 2006

Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein

scientific article published on 2 June 2016

HIV-1 protease inhibitors and the MDR1 multidrug transporter

scientific article published on January 15, 1998

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

scientific article published on March 1998

Hepatitis B Virus X Protein and Hepatocarcinogenesis

scientific article

Hepatitis B virus X gene and hepatocarcinogenesis.

scientific article published on 08 June 2011

Identification of microsatellite markers <1 Mb from the FMR1 CGG repeat and development of a single-tube tetradecaplex PCR panel of highly polymorphic markers for preimplantation genetic diagnosis of fragile X syndrome.

scientific article published on 7 January 2016

Improved co-expression of multiple genes in vectors containing internal ribosome entry sites (IRESes) from human genes.

scientific article

Improved high sensitivity screen for Huntington disease using a one-step triplet-primed PCR and melting curve assay

scientific article

Investigating the Promoter of FAT10 Gene in HCC Patients

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Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.

scientific article

Methylation profiles reveal distinct subgroup of hepatocellular carcinoma patients with poor prognosis

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Methylation-specific triplet-primed PCR and melting curve analysis as a rapid screening tool for identifying actionable FMR1 genotypes.

scientific article published on 5 September 2013

MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms.

scientific article

Paternal contribution of HLA-G*0106 significantly increases risk for pre-eclampsia in multigravid pregnancies.

scientific article published on 19 March 2008

Possible gene-gene interaction of KIR2DL4 with its cognate ligand HLA-G in modulating risk for preeclampsia.

scientific article published on 21 August 2009

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients

scientific article

Predicting potentially functional SNPs in drug-response genes.

scientific article published on April 2009

Role of miR-224 in Hepatocellular Carcinoma: A Tool for Possible Therapeutic Intervention?

scientific article published on April 1, 2011

Roles and Regulation of Long Noncoding RNAs in Hepatocellular Carcinoma

scientific article published on 23 July 2019

SNP web resources and their potential applications in personalized medicine.

scientific article published on September 2012

Screening for CGG repeat expansion in the FMR1 gene by melting curve analysis of combined 5' and 3' direct triplet-primed PCRs.

scientific article

Signatures of recent positive selection at the ATP-binding cassette drug transporter superfamily gene loci

scientific article published on 05 April 2007

Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity

scientific article

Single Nucleotide Polymorphisms Associated with MicroRNA Regulation.

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Single-Tube Dodecaplex PCR Panel of Polymorphic Microsatellite Markers Closely Linked to the DMPK CTG Repeat for Preimplantation Genetic Diagnosis of Myotonic Dystrophy Type 1.

scientific article

Single-step scalable-throughput molecular screening for Huntington disease.

scientific article published on 10 April 2008

Single-tube methylation-specific duplex-PCR assay for rapid and accurate diagnosis of Fragile X Mental Retardation 1-related disorders.

scientific article

Technical standards for hepatitis B virus X protein (HBx) research

scientific article

The promoter region of the MDR1 gene is largely invariant, but different single nucleotide polymorphism haplotypes affect MDR1 promoter activity differently in different cell lines.

scientific article published on 11 April 2006

Towards precision medicine: interrogating the human genome to identify drug pathways associated with potentially functional, population-differentiated polymorphisms

scientific article published on 03 October 2019

p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers.

scientific article published on April 2006

pfSNP: An integrated potentially functional SNP resource that facilitates hypotheses generation through knowledge syntheses.

scientific article published in January 2011