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List of works by Nicole Sampson

A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase

scientific article

A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol

scientific article

Access to Bicyclo[4.2.0]octene Monomers To Explore the Scope of Alternating Ring-Opening Metathesis Polymerization.

scientific article

Alternating ROMP copolymers containing charge-transfer units

scientific article published on August 2013

Alternating Ring-Opening Metathesis Polymerization (AROMP) of Hydrophobic and Hydrophilic Monomers Provides Oligomers with Side-Chain Sequence Control

scientific article published on 15 May 2018

Amino acid-bearing ROMP polymers with a stereoregular backbone

scientific article published in April 2006

Antibacterial Studies of Cationic Polymers with Alternating, Random, and Uniform Backbones ⬇️

scientific article published on March 17, 2011

Assessment of the Role of an Ω Loop of Cholesterol Oxidase: A Truncated Loop Mutant Has Altered Substrate Specificity† ⬇️

scientific article published on April 21, 1998

Beta1 integrin is an adhesion protein for sperm binding to eggs

scientific article published on May 2009

Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch.

scientific article

Characterization of fertilinβ-disintegrin binding specificity in sperm–egg adhesion

scientific article published on 01 April 2000

Cholesterol is not an essential source of nutrition for Mycobacterium tuberculosis during infection

scientific article

Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis.

scientific article published on May 2009

Cholesterol oxidase senses subtle changes in lipid bilayer structure

scientific article

Cholesterol oxidase: physiological functions

scientific article

Cholesterol oxidases: a study of nature's approach to protein design

scientific article

Comparison of Fertilinβ-Peptide-Substituted Polymers and Liposomes as Inhibitors of In Vitro Fertilization

scientific article published on 01 November 2003

Construction of a catalytically inactive cholesterol oxidase mutant: investigation of the interplay between active site-residues glutamate 361 and histidine 447.

scientific article published in June 2002

Correction to Hit Generation in TB Drug Discovery: From Genome to Granuloma

scientific article published on 06 May 2019

Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants

scientific article

Cyclic Alternating Ring-Opening Metathesis Polymerization (CAROMP). Rapid Access to Functionalized Cyclic Polymers ⬇️

scientific article published on September 3, 2010

Designing convergent chemistry curricula.

scientific article

Development of a high-throughput three-dimensional invasion assay for anti-cancer drug discovery

scientific article (publication date: 2013)

Dimyristoylated Peptides Incorporated into Liposomes Are Polyvalent Fertilin β Mimics

scientific article published on 01 October 2001

Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase

scientific article

Dynamic requirements for a functional protein hinge

scientific article

Entropy effects on protein hinges: the reaction catalyzed by triosephosphate isomerase

scientific article

Enzymatic β-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA

scientific article published in 2021

Evaluation of the role of His447 in the reaction catalyzed by cholesterol oxidase

scientific article published on 01 December 1998

Fertilin beta peptidic liposomes inhibit fertilization by steric blockage.

scientific article published in March 2004

Fucose-Galactose Polymers Inhibit Cholera Toxin Binding to Fucosylated Structures and Galactose-Dependent Intoxication of Human Enteroids

scientific article published on 19 March 2020

Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host Cells.

scientific article published on 7 February 2018

Global gene expression analysis reveals a role for the alpha 1 integrin in renal pathogenesis.

scientific article published on 10 July 2001

Glycopolymer induction of mouse sperm acrosomal exocytosis shows highly cooperative self-antagonism

scientific article published on 02 May 2016

Hit Generation in TB Drug Discovery: From Genome to Granuloma

scientific article published on 31 January 2018

Incorporation of Large Cycloalkene Rings into Alternating Copolymers Allows Control of Glass Transition and Hydrophobicity

Increased Expression ofBrevibacterium sterolicumCholesterol Oxidase inEscherichia coliby Genetic Modification

scientific article published on 01 April 1998

Increased Polymer Length of Oligopeptide-Substituted Polynorbornenes with LiCl

scientific article published on 01 March 2003

Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration.

scientific article

Inhibition of the M. tuberculosis 3β-hydroxysteroid dehydrogenase by azasteroids

scientific article

IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria

scientific article published on 04 March 2020

Library screening studies to investigate substrate specificity in the reaction catalyzed by cholesterol oxidase.

scientific article

Mapping peptide thiol accessibility in membranes using a quaternary ammonium isotope-coded mass tag (ICMT).

scientific article

Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities

scientific article published on 03 May 2019

Multivalent fertilinbeta oligopeptides: the dependence of fertilization inhibition on length and density

scientific article

Mycobacterium tuberculosis Exploits a Heterohexameric Enoyl-CoA Hydratase Retro-Aldolase Complex for Cholesterol Catabolism

scientific article published on 07 October 2019

Mycobacterium tuberculosis utilizes a unique heterotetrameric structure for dehydrogenation of the cholesterol side chain

scientific article

Off-resonance TROSY (R1 rho - R1) for quantitation of fast exchange processes in large proteins

scientific article published on 01 October 2003

Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism

scientific journal article

Peptides corresponding to the epidermal growth factor-like domain of mouse fertilin: Synthesis and biological activity

scientific article published on 01 January 1998

Phospholipase D2 loss results in increased blood pressure via inhibition of the endothelial nitric oxide synthase pathway.

scientific article

Polymeric ADAM protein mimics interrogate mammalian sperm-egg binding.

scientific article published on March 2009

Role of the hemopexin domain of matrix metalloproteinases in cell migration

scientific article

Romping the cellular landscape: linear scaffolds for molecular recognition

scientific article published on 14 June 2006

Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase

scientific journal article

Scope of the ring-opening metathesis polymerization (ROMP) reaction of 1-substituted cyclobutenes.

scientific article published on August 2010

Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease

scientific article published on January 2013

Shrinking the FadE proteome of Mycobacterium tuberculosis: insights into cholesterol metabolism through identification of an α2β2 heterotetrameric acyl coenzyme A dehydrogenase family

scientific article

Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9

scientific article

Structural analysis of fertilinβ cyclic peptide mimics that are ligands for α6β1 integrin

scientific article published on 01 February 2002

Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox activity

scientific article (publication date: 7 March 2003)

Sugars Require Rigid Multivalent Displays for Activation of Mouse Sperm Acrosomal Exocytosis

scientific article published on 16 May 2017

Surface molecular recognition.

scientific article

Synthesis of copolymers by alternating ROMP (AROMP).

scientific article published on March 2009

Targeting the Hemopexin-like Domain of Latent Matrix Metalloproteinase-9 (proMMP-9) with a Small Molecule Inhibitor Prevents the Formation of Focal Adhesion Junctions.

scientific article

The Binding and Release of Oxygen and Hydrogen Peroxide Are Directed by a Hydrophobic Tunnel in Cholesterol Oxidase †

scientific article

The Mce3R Regulon Is Required for 6-Azasteroid Potentiation of Anti-TB Drug Activity

The Mce3R Regulon Is Required for 6-Azasteroid Potentiation of Anti-TB Drug Activity

Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase.

scientific article

Updating and curating metabolic pathways of TB.

scientific article published on January 2013

Use of an Isotope-Coded Mass Tag (ICMT) Method To Determine the Orientation of Cholesterol Oxidase on Model Membranes

scientific article published on 28 August 2018

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