List of works - Selena M Sagan

6th Canadian Symposium on Hepatitis C Virus: Delivering a cure for hepatitis C infection—What are the remaining gaps?

article

A Complex Network of Interactions between S282 and G283 of Hepatitis C Virus Nonstructural Protein 5B and the Template Strand Affects Susceptibility to Sofosbuvir and Ribavirin

scientific article published on 11 January 2016

A highly sensitive strand-specific multiplex RT-qPCR assay for quantitation of Zika virus replication

scientific article published on 30 May 2022

A survey of medication preparation and administration practices among members of the Canadian Anesthesiologists’ Society

article

Analysis of the T Cell Response to Zika Virus and Identification of a Novel CD8+ T Cell Epitope in Immunocompetent Mice

scientific article (publication date: 23 February 2017)

Beyond sites 1 and 2, miR-122 target sites in the HCV genome have negligible contributions to HCV RNA accumulation in cell culture

scientific article published on 17 January 2019

Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses

scientific article

Combating hepatitis C virus by targeting microRNA-122 using locked nucleic acids.

scientific article published on August 2012

Contemporary Zika Virus Isolates Induce More dsRNA and Produce More Negative-Strand Intermediate in Human Astrocytoma Cells

scholarly article by Trisha R Barnard et al published 19 December 2018 in Viruses

Cysteine residues of Carnation Italian Ringspot virus p19 suppressor of RNA silencing maintain global structural integrity and stability for siRNA binding

scientific article published on 31 March 2009

Design and screening of siRNAs against highly structured RNA targets

scientific article published on January 2013

Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism.

scientific article

Dissecting noncoding and pathogen RNA-protein interactomes

scientific article

Effects of pH and salt concentration on the siRNA binding activity of the RNA silencing suppressor protein p19

scientific article published on 04 June 2007

Enhancement of hepatitis C viral RNA abundance by precursor miR-122 molecules

scientific article published on 08 October 2013

Hepatitis C Contamination of Medication Vials Accessed with Sterile Needles and Syringes

scientific article published on 01 August 2019

Hepatitis C virus and human miR-122: insights from the bench to the clinic

scientific article

Higher Cytopathic Effects of a Zika Virus Brazilian Isolate from Bahia Compared to a Canadian-Imported Thai Strain

scientific article published on 27 January 2018

Highlights of the Fourth Canadian Symposium on Hepatitis C: Moving towards a National Action Plan

scientific article published on 27 April 2016

Inhibition of siRNA Binding to a p19 Viral Suppressor of RNA Silencing by Cysteine Alkylation

scientific article published on 01 January 2007

Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex.

scientific article

MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner

scientific article published on 01 May 2020

Modulation of GB virus B RNA abundance by microRNA-122: dependence on and escape from microRNA-122 restriction

scientific article published on 24 April 2013

Molecular Determinants of Flavivirus Virion Assembly

scientific article published in May 2021

Molecular biology. RNAi, Antiviral after all.

scientific article published on October 2013

Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis

scientific article published in Scientific Reports

Peroxisome proliferator-activated receptor alpha antagonism inhibits hepatitis C virus replication

scientific article published on January 2006

Plasmacytoid dendritic cells as guardians in hepatitis C virus-infected liver.

scientific article

Stabilized recombinant suppressors of RNA silencing: functional effects of linking monomers of Carnation Italian Ringspot virus p19.

scientific article published on 12 October 2007

Studies of a viral suppressor of RNA silencing p19-CFP fusion protein: a FRET-based probe for sensing double-stranded fluorophore tagged small RNAs

scientific article

Studies of the interaction of the viral suppressor of RNA silencing protein p19 with small RNAs using fluorescence polarization.

scientific article

The 3rd Canadian Symposium on Hepatitis C Virus: expanding care in the interferon-free era.

scientific article published on October 2014

The 5th Canadian Symposium on Hepatitis C Virus: We Are Not Done Yet-Remaining Challenges in Hepatitis C.

scientific article published on 24 October 2016

The 7th Canadian Symposium on Hepatitis C Virus: “Toward Elimination of HCV: How to Get There”

article

The Diverse Roles of microRNAs at the Host⁻Virus Interface

scholarly article by Annie Bernier published in August 2018

The Second Canadian Symposium on hepatitis C virus: a call to action

scientific article published on November 2013

The efficacy of siRNAs against hepatitis C virus is strongly influenced by structure and target site accessibility

scientific article published on May 2010

The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication

scientific article published in February 2006

The miR-17∼92 microRNA Cluster Is a Global Regulator of Tumor Metabolism.

scientific article published on 3 August 2016

Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus

scientific article

Unraveling the Mysterious Interactions Between Hepatitis C Virus RNA and Liver-Specific MicroRNA-122.

scientific article

Virus discovery reveals frequent infection by diverse novel members of the Flaviviridae in wild lemurs

Zika Virus: Emergence, Phylogenetics, Challenges, and Opportunities

scientific article

Zika virus NS3 and NS5 proteins determine strain-dependent differences in dsRNA accumulation in a host cell type-dependent manner

scientific article published in 2023

Zika virus infection: induction, restriction and evasion of host interferon responses

article

cis-Acting RNA elements in the hepatitis C virus RNA genome

scientific article published on 07 January 2015

miR-122 and Ago interactions with the HCV genome alter the structure of the viral 5' terminus.

scientific article published in June 2019

miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11.

scientific article

List of works by Selena M Sagan

6th Canadian Symposium on Hepatitis C Virus: Delivering a cure for hepatitis C infection—What are the remaining gaps?

A Complex Network of Interactions between S282 and G283 of Hepatitis C Virus Nonstructural Protein 5B and the Template Strand Affects Susceptibility to Sofosbuvir and Ribavirin

A highly sensitive strand-specific multiplex RT-qPCR assay for quantitation of Zika virus replication

A survey of medication preparation and administration practices among members of the Canadian Anesthesiologists’ Society

Analysis of the T Cell Response to Zika Virus and Identification of a Novel CD8+ T Cell Epitope in Immunocompetent Mice

Beyond sites 1 and 2, miR-122 target sites in the HCV genome have negligible contributions to HCV RNA accumulation in cell culture

Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses

Combating hepatitis C virus by targeting microRNA-122 using locked nucleic acids.

Contemporary Zika Virus Isolates Induce More dsRNA and Produce More Negative-Strand Intermediate in Human Astrocytoma Cells

Cysteine residues of Carnation Italian Ringspot virus p19 suppressor of RNA silencing maintain global structural integrity and stability for siRNA binding

Design and screening of siRNAs against highly structured RNA targets

Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism.

Dissecting noncoding and pathogen RNA-protein interactomes

Effects of pH and salt concentration on the siRNA binding activity of the RNA silencing suppressor protein p19

Enhancement of hepatitis C viral RNA abundance by precursor miR-122 molecules

Hepatitis C Contamination of Medication Vials Accessed with Sterile Needles and Syringes

Hepatitis C virus and human miR-122: insights from the bench to the clinic

Higher Cytopathic Effects of a Zika Virus Brazilian Isolate from Bahia Compared to a Canadian-Imported Thai Strain

Highlights of the Fourth Canadian Symposium on Hepatitis C: Moving towards a National Action Plan

Inhibition of siRNA Binding to a p19 Viral Suppressor of RNA Silencing by Cysteine Alkylation

Inhibition of siRNA Binding to a p19 Viral Suppressor of RNA Silencing by Cysteine Alkylation

Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex.

MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner

Modulation of GB virus B RNA abundance by microRNA-122: dependence on and escape from microRNA-122 restriction

Molecular Determinants of Flavivirus Virion Assembly

Molecular biology. RNAi, Antiviral after all.

Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis

Peroxisome proliferator-activated receptor alpha antagonism inhibits hepatitis C virus replication

Plasmacytoid dendritic cells as guardians in hepatitis C virus-infected liver.

Stabilized recombinant suppressors of RNA silencing: functional effects of linking monomers of Carnation Italian Ringspot virus p19.

Studies of a viral suppressor of RNA silencing p19-CFP fusion protein: a FRET-based probe for sensing double-stranded fluorophore tagged small RNAs

Studies of the interaction of the viral suppressor of RNA silencing protein p19 with small RNAs using fluorescence polarization.

The 3rd Canadian Symposium on Hepatitis C Virus: expanding care in the interferon-free era.

The 5th Canadian Symposium on Hepatitis C Virus: We Are Not Done Yet-Remaining Challenges in Hepatitis C.

The 7th Canadian Symposium on Hepatitis C Virus: “Toward Elimination of HCV: How to Get There”

The Diverse Roles of microRNAs at the Host⁻Virus Interface

The Second Canadian Symposium on hepatitis C virus: a call to action

The efficacy of siRNAs against hepatitis C virus is strongly influenced by structure and target site accessibility

The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication

The miR-17∼92 microRNA Cluster Is a Global Regulator of Tumor Metabolism.

Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus

Unraveling the Mysterious Interactions Between Hepatitis C Virus RNA and Liver-Specific MicroRNA-122.

Virus discovery reveals frequent infection by diverse novel members of the Flaviviridae in wild lemurs

Zika Virus: Emergence, Phylogenetics, Challenges, and Opportunities

Zika virus NS3 and NS5 proteins determine strain-dependent differences in dsRNA accumulation in a host cell type-dependent manner

Zika virus infection: induction, restriction and evasion of host interferon responses

cis-Acting RNA elements in the hepatitis C virus RNA genome

miR-122 and Ago interactions with the HCV genome alter the structure of the viral 5' terminus.

miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11.