List of works by Douglas G Widman

A new quaternary structure epitope on dengue virus serotype 2 is the target of durable type-specific neutralizing antibodies

scientific article

Analyzing the Human Serum Antibody Responses to a Live Attenuated Tetravalent Dengue Vaccine Candidate

article

Bioassay for the measurement of type-I interferon activity.

scientific article published on January 2013

Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain

scientific article

Construction and characterization of a second-generation pseudoinfectious West Nile virus vaccine propagated using a new cultivation system.

scientific article

Construction and evaluation of a chimeric pseudoinfectious virus vaccine to prevent Japanese encephalitis.

scientific article

Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika Virus

scientific article

Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone

scientific article published on January 2017

Evaluation of RepliVAX WN, a single-cycle flavivirus vaccine, in a non-human primate model of West Nile virus infection

scientific article

Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1.

scientific article published on 9 March 2016

Human dengue virus serotype 2 neutralizing antibodies target two distinct quaternary epitopes.

scientific article

In vitro toxicity and efficacy of verdinexor, an exportin 1 inhibitor, on opportunistic viruses affecting immunocompromised individuals

scientific article published in PLoS ONE

Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling.

scientific article published on 5 January 2012

Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to DENV4 Infection and Vaccination

scientific article (publication date: 28 December 2016)

Neutralization mechanism of a highly potent antibody against Zika virus

scientific article

Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation.

scientific article

Repeated in vivo stimulation of T and B cell responses in old mice generates protective immunity against lethal West Nile virus encephalitis

scientific article

RepliVAX WN, a single-cycle flavivirus vaccine to prevent West Nile disease, elicits durable protective immunity in hamsters

scientific article published on 25 July 2009

Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model

scientific article published on 24 August 2015

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

scientific article

Third-generation flavivirus vaccines based on single-cycle, encapsidation-defective viruses

scientific article published on January 2008

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