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List of works by Hongyan Qin

Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age

scientific article (publication date: 2011)

Blocking Notch signal in myeloid cells alleviates hepatic ischemia reperfusion injury by repressing the activation of NF-κB through CYLD

scientific article published on 29 September 2016

Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling.

scientific article published on 8 August 2011

Crosstalk between hepatic tumor cells and macrophages via Wnt/β-catenin signaling promotes M2-like macrophage polarization and reinforces tumor malignant behaviors

scientific article published on 18 July 2018

Cytotherapy with M1-polarized macrophages ameliorates liver fibrosis by modulating immune microenvironment in mice.

scientific article published on 5 June 2017

Disruption of Notch signaling aggravates irradiation-induced bone marrow injury, which is ameliorated by a soluble Dll1 ligand through Csf2rb2 upregulation

scientific article (publication date: 18 May 2016)

FHL1C induces apoptosis in Notch1-dependent T-ALL cells through an interaction with RBP-J.

scientific article

Forced Activation of Notch in Macrophages Represses Tumor Growth by Upregulating miR-125a and Disabling Tumor-Associated Macrophages

scientific article published on 12 January 2016

Foxp3(+) T cells regulate immunoglobulin a selection and facilitate diversification of bacterial species responsible for immune homeostasis

scientific article

Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior

scientific article

Myeloid-Specific Blockade of Notch Signaling by RBP-J Knockout Attenuates Spinal Cord Injury Accompanied by Compromised Inflammation Response in Mice.

scientific article published on 26 October 2014

Myeloid-specific disruption of recombination signal binding protein Jκ ameliorates hepatic fibrosis by attenuating inflammation through cylindromatosis in mice

scientific article published on 24 November 2014

Myeloid-specific targeting of Notch ameliorates murine renal fibrosis via reduced infiltration and activation of bone marrow-derived macrophage.

scientific article published on 11 April 2018

NOTCH Signaling via WNT Regulates the Proliferation of Alternative, CCR2-Independent Tumor-Associated Macrophages in Hepatocellular Carcinoma

scientific article published on 02 July 2019

Notch Signaling Modulates Macrophage Polarization and Phagocytosis Through Direct Suppression of Signal Regulatory Protein α Expression

scientific article published on 30 July 2018

Overexpression of Notch ligand Dll1 in B16 melanoma cells leads to reduced tumor growth due to attenuated vascularization.

scientific article published on 24 June 2011

RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2

scientific article

Targeted delivery of miR-99b reprograms tumor-associated macrophage phenotype leading to tumor regression

scientific article published on 01 September 2020

The LIM domain protein FHL1C interacts with tight junction protein ZO-1 contributing to the epithelial-mesenchymal transition (EMT) of a breast adenocarcinoma cell line.

scientific article published on 19 March 2014

The PcG protein HPC2 inhibits RBP-J-mediated transcription by interacting with LIM protein KyoT2

scientific article (publication date: 14 February 2005)

The transcriptional repression activity of KyoT2 on the Notch/RBP-J pathway is regulated by PIAS1-catalyzed SUMOylation.

scientific article published on 12 April 2007