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List of works by Irene Frischauf

2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size.

scientific article

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

scientific article published on 03 February 2009

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription

scientific article published on 22 December 2015

Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N-terminus.

scientific article published on 13 December 2017

Blockage of Store-Operated Ca2+ Influx by Synta66 is Mediated by Direct Inhibition of the Ca2+ Selective Orai1 Pore

scientific article published on 06 October 2020

CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions

scientific article published on 22 December 2020

Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.

scientific article published on 29 August 2012

Communication between N-terminus and Loop2 tunes Orai activation.

scientific article published on 13 December 2017

Cooperativeness of Orai cytosolic domains tunes subtype-specific gating.

scientific article

Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

scientific article published on 10 January 2008

Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant

scientific article published on 14 April 2009

Live-cell imaging of ER-PM contact architecture by a novel TIRFM approach reveals extension of junctions in response to store-operated Ca(2+)-entry

scientific article published on 19 October 2016

Molecular Determinants within N Terminus of Orai3 Protein That Control Channel Activation and Gating ⬇️

scientific article published on September 9, 2011

Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant

scientific article published on 08 June 2009

Proliferation of aligned mammalian cells on laser-nanostructured polystyrene.

scientific article

Resting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cells

scientific article

STIM1 activation of Orai1

scientific article published on 30 November 2018

Science CommuniCa2+tion Developing Scientific Literacy on Calcium: The Involvement of CRAC Currents in Human Health and Disease

scientific article published on 05 June 2022

Sequential activation of STIM1 links Ca2+ with luminal domain unfolding

scientific article published on 19 November 2019

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

scientific article

Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.

scientific article published on 28 November 2017

UV surface modification of a new nanocomposite polymer to improve cytocompatibility

scientific article published on January 2007

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