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List of works by Xiong Guo

A Genomewide Integrative Analysis of GWAS and eQTLs Data Identifies Multiple Genes and Gene Sets Associated with Obesity.

scientific article published on 8 May 2018

A bivariate genome-wide association study identifies ADAM12 as a novel susceptibility gene for Kashin-Beck disease

scientific article published on 22 August 2016

Abnormal expression of Col X, PTHrP, TGF-beta, bFGF, and VEGF in cartilage with Kashin-Beck disease

scientific article published in January 2006

Abnormal expression of chondroitin sulphate N-acetylgalactosaminyltransferase 1 and Hapln-1 in cartilage with Kashin–Beck disease and primary osteoarthritis ⬇️

scientific article published on 08 June 2013

Altered Aggrecan Synthesis and Collagen Expression Profiles in Chondrocytes from Patients with Kashin—Beck Disease and Osteoarthritis ⬇️

scientific article published on January 1, 2012

Altered expression of chondroitin sulfate structure modifying sulfotransferases in the articular cartilage from adult osteoarthritis and Kashin-Beck disease

scientific article published on 5 March 2017

Association of TNF-α and Fas gene promoter polymorphism with the risk of Kashin–Beck disease in Northwest Chinese population ⬇️

scientific article published on March 20, 2012

Associations Between Selenium Content in Hair and Kashin-Beck Disease/Keshan Disease in Children in Northwestern China: a Prospective Cohort Study

scientific article published on 6 October 2017

Biological Analysis of Gene Expression and Clinical Variables Suggest FZD1 as a Novel Biomarker for Patients with Kashin-Beck Disease, an Endemic Osteoarthritis in China

article

Brief Report: Genome-Wide Association Study Identifies ITPR2 as a Susceptibility Gene for Kashin-Beck Disease in Han Chinese

article

Changes of death receptor regulator expression in the articular cartilage of patients with Kashin-Beck disease

scientific article published on November 1, 2011

Changing Grains for the Prevention and Treatment of Kashin-Beck Disease in Children: a Meta-analysis

scientific article published in April 2015

Chondrocyte apoptosis and expression of Bcl-2, Bax, Fas, and iNOS in articular cartilage in patients with Kashin-Beck disease.

scientific article

Chondrocyte apoptosis and the expression of Bcl-2, Bax, Fas and iNos in articular cartilage in Kashin-Beck disease

scientific article

Chondrocytes damage induced by T-2 toxin via Wnt/β-catenin signaling pathway is involved in the pathogenesis of an endemic osteochondropathy, Kashin-Beck disease

scientific article published on 14 October 2017

Comparative analysis of gene expression profiles between primary knee osteoarthritis and an osteoarthritis endemic to Northwestern China, Kashin-Beck disease

scientific article

Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis.

scientific article published on 24 June 2008

Comparative analysis of signaling pathways in peripheral blood from patients with Kashin-Beck disease and osteoarthritis

scientific article

Comparison of apoptosis of articular chondrocytes in the pathogenesis of Kashin-beck disease and primary osteoarthritis

scientific article

Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis

scientific article

Defective autophagy in chondrocytes with Kashin-Beck disease but higher than osteoarthritis

scientific article

Detection of serum proteomic changes and discovery of serum biomarkers for Kashin-Beck disease using surface-enhanced laser desorption ionization mass spectrometry (SELDI-TOF MS).

scientific article

Development and validation of a quality of life instrument for Kashin-Beck disease: an endemic osteoarthritis in China ⬇️

scientific article published on March 16, 2012

Dietary exosome-miR-23b may be a novel therapeutic measure for preventing Kashin-Beck disease

scientific article published on 22 February 2018

Epidemiological characters of Kashin-Beck disease in nuclear families

scientific article

Evaluation of the Sensitivity and Specificity of the New Clinical Diagnostic and Classification Criteria for Kashin-Beck Disease, an Endemic Osteoarthritis, in China

scientific article published on February 2017

Evaluation of the therapeutic effect of treatment with intra-articular hyaluronic acid in knees for Kashin-Beck disease: a meta-analysis

scientific article published on 30 April 2014

Exome sequencing identified FGF12 as a novel candidate gene for Kashin-Beck disease

scientific article published on 20 August 2015

Exploring Genome-wide DNA Methylation Profiles Altered in Kashin-Beck Disease Using Infinium Human Methylation 450 Bead Chips ⬇️

Expression Profile Analysis of Selenium-Related Genes in Peripheral Blood Mononuclear Cells of Patients with Keshan Disease

scientific article published on 17 November 2019

Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy Kashin-Beck Disease

scientific article

Expression profiles of genes involved in apoptosis and selenium metabolism in articular cartilage of patients with Kashin-Beck osteoarthritis

scientific article published on 4 December 2013

Familial aggregation and sibling heritability in Kashin-Beck disease

scientific article

Field synopsis and meta-analyses of genetic epidemiological evidence for Kashin-Beck disease, an endemic osteoarthropathy in China

scientific article published on 02 June 2016

Gene expression analysis suggests bone development-related genes GDF5 and DIO2 are involved in the development of Kashin-Beck disease in children rather than adults

scientific article

Genome-wide DNA methylation profiling of articular cartilage reveals significant epigenetic alterations in Kashin-Beck disease and osteoarthritis

scientific article

Genome-wide association study identifies COL2A1 locus involved in the hand development failure of Kashin-Beck disease

scientific article published on 06 January 2017

Genome-wide copy number variation study and gene expression analysis identify ABI3BP as a susceptibility gene for Kashin–Beck disease

article

Genome-wide gene expression analysis suggests an important role of hypoxia in the pathogenesis of endemic osteochondropathy Kashin-Beck disease

scientific article

Genome-wide gene expression analysis suggests an important role of suppressed immunity in pathogenesis of Kashin-Beck disease

scientific article

Genome-wide pathway-based association study implicates complement system in the development of Kashin-Beck disease in Han Chinese

scientific article published on 16 October 2014

Genome‐wide study identifies the regulatory gene networks and signaling pathways from chondrocyte and peripheral blood monocyte of Kashin–Beck disease ⬇️

scientific article published on July 9, 2012

Hyaluronic acid and glucosamine sulfate for adult Kashin-Beck disease: a cluster-randomized, placebo-controlled study

scientific article published on 12 November 2014

Identification of differentially expressed genes and pathways between primary osteoarthritis and endemic osteoarthritis (Kashin-Beck disease).

scientific article

Identified molecular mechanism of interaction between environmental risk factors and differential expression genes in cartilage of Kashin-Beck disease

scientific article published on December 2016

Imbalance of dietary nutrients and the associated differentially expressed genes and pathways may play important roles in juvenile Kashin-Beck disease

scientific article published on 6 February 2018

Individual and combined toxicity of T-2 toxin and deoxynivalenol on human C-28/I2 and rat primary chondrocytes

article

Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis

scientific article published on 7 March 2018

Integrative Multivariate Logistic Regression Analysis of Risk Factors for Kashin-Beck disease

scientific article

Investigation of MMP-1 genetic polymorphisms and protein expression and their effects on the risk of Kashin-Beck disease in the northwest Chinese Han population

scientific article published on 31 May 2016

Is It the Appropriate Time to Stop Applying Selenium Enriched Salt in Kashin-Beck Disease Areas in China?

scientific article

Long noncoding RNA expression profile reveals lncRNAs signature associated with extracellular matrix degradation in kashin-beck disease

scientific article published on 14 December 2017

Main source of drinking water and familial aggregation of Kashin-Beck disease: a population based on case-control family study

scientific article published in August 2009

Mass spectrometry-based proteomic analysis of Kashin-Beck disease ⬇️

scientific article published on July 8, 2010

Measuring health-related quality of life in Kashin–Beck disease using EQ-5D ⬇️

scientific article published on December 24, 2010

Mitochondrial function is altered in articular chondrocytes of an endemic osteoarthritis, Kashin-Beck disease

scientific article

Morphology and phenotype expression of types I, II, III, and X collagen and MMP-13 of chondrocytes cultured from articular cartilage of Kashin-Beck Disease.

scientific article

Nutrients Other than Selenium Are Important for Promoting Children's Health in Kashin-Beck Disease Areas

scientific article published on 18 September 2017

PAPA: a flexible tool for identifying pleiotropic pathways using genome-wide association study summaries

scientific article published on 14 November 2015

PPARGC1B gene is associated with Kashin-Beck disease in Han Chinese

scientific article published on 23 April 2016

Polymorphism in rs2229783 of the Alpha 1(XI) Collagen Gene Is Associated with Susceptibility to but not Severity of Kashin-Beck Disease in a Northwest Chinese Han Population

article

Population-based comparative analysis of differentially expressed genes between Kashin-Beck disease grades I and II.

scientific article

Prevalence of Selenium, T-2 Toxin, and Deoxynivalenol in Kashin-Beck Disease Areas in Qinghai Province, Northwest China

scientific article published on 9 September 2015

RNA-seq analysis reveals different gene ontologies and pathways in rheumatoid arthritis and Kashin-Beck disease

article

Regulatory gene networks and signaling pathways from primary osteoarthritis and Kashin–Beck disease, an endemic osteoarthritis, identified by three analysis software ⬇️

scientific article published on October 13, 2012

Reliability and validation of the joint dysfunction index as a new assessment instrument for therapeutic efficacy for Kashin-Beck disease

scientific article published on 19 April 2016

Reliability and validity of the EQ-5D-3L for Kashin-Beck disease in China

scientific article

SWGDT: A sliding window-based genotype dependence testing tool for genome-wide susceptibility gene scan

scientific article published on 15 July 2015

Salt-Rich Selenium for Prevention and Control Children with Kashin-Beck Disease: a Meta-analysis of Community-Based Trial

scientific article published on 23 July 2015

Selenium and Iodine Levels in Subjects with Kashin-Beck Disease: a Meta-analysis

scientific article published on 8 August 2015

The Effect of Disordered Glycometabolism of Kashin-Beck Disease on the Function of Chondrocytes

scientific article

The effects of T-2 toxin on the prevalence and development of Kashin-Beck disease in China: a meta-analysis and systematic review

article

The efficacy and safety of intra-articular injection of hyaluronic acid in the knee and physical therapy agents to treat Kashin-Beck disease: A prospective interventional study

scientific article published on 19 May 2016

The expression of p-ATF2 involved in the chondeocytes apoptosis of an endemic osteoarthritis, Kashin-Beck disease

scientific article

The potential biochemical markers of Kashin-Beck disease: a meta-analysis

scientific article

The potential of induced pluripotent stem cells as a tool to study skeletal dysplasias and cartilage-related pathologic conditions

scientific article published on 02 December 2016

The roles of selenium, insulin-like growth factor binding protein 2 and suppressor of cytokine signaling 3 in the pathogenesis of Kashin-Beck disease

scientific article published on 21 April 2016

To screen the effective software for analysing gene interactions from Kashin-Beck disease genome profiling pathway and network, according to the tool of GeneMANIA.

scientific article published on January 2015

Trans-omics pathway analysis suggests that eQTLs contribute to chondrocyte apoptosis of Kashin-Beck disease through regulating apoptosis pathway expression

scientific article published on 11 October 2014

Zinc: the Other Suspected Environmental Factor in Kashin-Beck Disease in Addition to Selenium

scientific article published on 21 February 2017

[Association of genetic polymorphism of 14 STR loci on chromosome 2 with Kashin-Beck disease].

scientific article

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