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List of works by Claes M. Gustafsson

A chromatin-remodeling protein is a component of fission yeast mediator

scientific article published on 9 July 2010

A family of putative transcription termination factors shared amongst metazoans and plants

scientific article published on October 2005

A genome-wide role for CHD remodelling factors and Nap1 in nucleosome disassembly

scientific article published on 17 May 2007

A hybrid G-quadruplex structure formed between RNA and DNA explains the extraordinary stability of the mitochondrial R-loop

scientific article published on 10 September 2012

Absolute yeast mitochondrial proteome quantification reveals trade-off between biosynthesis and energy generation during diauxic shift

scientific article published on 17 March 2020

Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing

scientific article published on 14 December 2020

Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function

scientific article

An Adaptable High-Throughput Technology Enabling the Identification of Specific Transcription Modulators

scientific article published on 31 January 2017

Author Correction: MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures

scientific article published on 21 November 2019

Conserved sequence box II directs transcription termination and primer formation in mitochondria

scientific article published on 21 June 2006

Correction for Szilagyi et al., "Cyclin-Dependent Kinase 8 Regulates Mitotic Commitment in Fission Yeast".

scientific article published on 11 August 2017

Cryo-EM reveals promoter DNA binding and conformational flexibility of the general transcription factor TFIID.

scientific article

Cyclin C influences the timing of mitosis in fission yeast

scientific article published on 17 May 2017

Cyclin-dependent kinase 8 regulates mitotic commitment in fission yeast

scientific article published on 26 March 2012

DNA replication and transcription in mammalian mitochondria

scientific article published on January 2007

Design parameters to control synthetic gene expression in Escherichia coli

scientific article published in 2009

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

scientific article published on 03 October 2019

Distinct differences in chromatin structure at subtelomeric X and Y' elements in budding yeast

scientific article

Emerging roles of Cdk8 in cell cycle control

scientific article published on May 2013

Engineering proteinase K using machine learning and synthetic genes

scientific article

Essential genetic interactors of SIR2 required for spatial sequestration and asymmetrical inheritance of protein aggregates

scientific article (publication date: July 2014)

G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation

scientific article

Gene Designer: a synthetic biology tool for constructing artificial DNA segments

scientific article

Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions

scientific article published on April 2006

Hereditary myopathy with early respiratory failure is associated with misfolding of the titin fibronectin III 119 subdomain.

scientific article published on 15 February 2014

Histone modifications influence mediator interactions with chromatin

scientific article

Human Mitochondrial Transcription Factor B2 Is Required for Promoter Melting during Initiation of Transcription

scientific article published on 27 December 2016

Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro

scholarly article

Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro

scientific article

In vitro-reconstituted nucleoids can block mitochondrial DNA replication and transcription.

scientific article published on 26 June 2014

In vivo mutagenesis reveals that OriL is essential for mitochondrial DNA replication

scientific article published on 23 October 2012

In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication

scientific article (publication date: December 2014)

LRPPRC is a mitochondrial matrix protein that is conserved in metazoans

scientific article published on 13 July 2010

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

scientific article

Loss of the Mediator subunit Med20 affects transcription of tRNA and other non-coding RNA genes in fission yeast

scientific article

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures.

scientific article published on 24 July 2015

MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication

scientific article

MTERF1 gives mtDNA an unusual twist

scientific article published on 01 July 2010

MTERF2 is a nucleoid component in mammalian mitochondria

scientific article

MTERF3 is a negative regulator of mammalian mtDNA transcription

scientific article

MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome

scientific article

Maintenance and Expression of Mammalian Mitochondrial DNA.

scientific article published on 24 March 2016

Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription

scientific article published on 20 June 2010

Mammalian mitochondrial DNA replication and mechanisms of deletion formation

scientific article published on 24 September 2020

Mammalian transcription factor A is a core component of the mitochondrial transcription machinery

scientific article

Mediator can regulate mitotic entry and direct periodic transcription in fission yeast

scientific article

Mediator influences telomeric silencing and cellular life span

scientific article published on 11 April 2011

Mediator promotes CENP-a incorporation at fission yeast centromeres.

scientific article

Mediator tail subunits can form amyloid-like aggregates in vivo and affect stress response in yeast

scientific article

Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome

scientific article

Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication

scientific article published on 01 January 2010

Mitochondrial transcription and its regulation in mammalian cells

scientific article published on 8 February 2007

Mitochondrial transcription termination factor 1 directs polar replication fork pausing

scientific article published on 25 April 2016

Molecular phylogenetics of ascomycotal adhesins--a novel family of putative cell-surface adhesive proteins in fission yeasts

scientific article published on 17 August 2007

Mutations in mitochondrial DNA causing tubulointerstitial kidney disease.

scientific article

Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA.

scientific article

POLRMT mutations impair mitochondrial transcription causing neurological disease

scientific article published on 18 February 2021

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.

scientific article published on 05 August 2016

Protein sliding and DNA denaturation are essential for DNA organization by human mitochondrial transcription factor A

scientific article published in Nature Communications

RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing

scientific article

RNase H1 directs origin-specific initiation of DNA replication in human mitochondria

article published in 2019

Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer

scientific article published on 16 June 2020

Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element.

scientific article published on 7 August 2015

Ribonucleotides embedded in template DNA impair mitochondrial RNA polymerase progression

Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genome

scientific article published on 30 November 2011

Separating and Segregating the Human Mitochondrial Genome

scientific article published on 14 September 2018

Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers

scientific article published on 30 June 2015

Small-molecule inhibitors of human mitochondrial DNA transcription

scientific article published on 04 January 2021

Structural elements required for the cooperative binding of the herpes simplex virus origin binding protein to oriS reside in the N-terminal part of the protein

scientific article published on August 25, 1992

Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain

scientific article

Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis

scientific article

TEFM is a potent stimulator of mitochondrial transcription elongation in vitro

scientific article published on 17 February 2015

TEFM regulates both transcription elongation and RNA processing in mitochondria.

scientific article

The DNA Ligands Influence the Interactions between the Herpes Simplex Virus 1 Origin Binding Protein and the Single Strand DNA-binding Protein, ICP-8

scientific article published on August 11, 1995

The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation

scientific article published on 20 January 2014

The classical srb4-138 mutant allele causes dissociation of yeast Mediator

scientific article published on 24 August 2006

The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II.

scholarly article

The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication.

scientific article published on 22 June 2015

The human mitochondrial transcription termination factor (mTERF) is fully active in vitro in the non-phosphorylated form

scientific article

The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis

scientific article

The structural and functional role of Med5 in the yeast Mediator tail module

scientific article

The transcription machinery in mammalian mitochondria

scientific article

The yeast Mediator complex and its regulation

scientific article

Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways

scientific article published on 29 February 2008

Whole exome sequencing reveals mutations in NARS2 and PARS2, encoding the mitochondrial asparaginyl-tRNA synthetase and prolyl-tRNA synthetase, in patients with Alpers syndrome

scientific article published on 23 October 2014

Yeast RNA Polymerase II Transcription Reconstituted with Purified Proteins

scientific article published on July 1, 1997

Yeast mismatch repair components are required for stable inheritance of gene silencing

scientific article published on 29 May 2020