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List of works by Florence Lefebvre

A new regulation of IL-6 production in adult cardiomyocytes by beta-adrenergic and IL-1 beta receptors and induction of cellular hypertrophy by IL-6 trans-signalling

scientific journal article

A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes.

scientific article

An SRF/miR-1 axis regulates NCX1 and annexin A5 protein levels in the normal and failing heart

scientific article published on 22 February 2013

Calmodulin kinase II inhibition limits the pro-arrhythmic Ca2+ waves induced by cAMP-phosphodiesterase inhibitors.

scientific article

Contribution of BKCa channels to vascular tone regulation by PDE3 and PDE4 is lost in heart failure

scientific article published on 01 January 2019

Control by circulating factors of mitochondrial function and transcription cascade in heart failure: a role for endothelin-1 and angiotensin II.

scientific article published on 8 May 2009

Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.

scientific article published in October 2004

PDE4 and mAKAPβ are nodal organizers of β2-ARs nuclear PKA signaling in cardiac myocytes

scientific article

Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice

scientific journal article

Reconciling depressed Ca2+ sparks occurrence with enhanced RyR2 activity in failing mice cardiomyocytes.

scientific article

Sexual dimorphism of doxorubicin-mediated cardiotoxicity: potential role of energy metabolism remodeling

scientific article published on 24 November 2014

Specific Activation of the Alternative Cardiac Promoter of Cacna1c by the Mineralocorticoid Receptor

scientific article published on 21 February 2018

Standard and Strain Measurements by Echocardiography Detect Early Overloaded Right Ventricular Dysfunction: Validation against Hemodynamic and Myocyte Contractility Changes in a Large Animal Model.

scientific article published on 29 August 2017

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