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List of works by Jean-Luc Ravanat

2'-deoxyguanosine oxidation is associated with decrease in the DNA-binding activity of the transcription factor Sp1 in liver and kidney from diabetic and insulin-resistant rats.

scientific article

A combined proteomic and targeted analysis unravels new toxic mechanisms for zinc oxide nanoparticles in macrophages

scientific article published on 19 December 2015

A microarray to measure repair of damaged plasmids by cell lysates.

scientific article published on 28 August 2008

Addressing the competitive formation of tandem DNA lesions by a nucleobase peroxyl radical: a DFT-D screening

scientific article published on 01 May 2013

Analysis of fluoroquinolone-mediated photosensitization of 2'-deoxyguanosine, calf thymus and cellular DNA: determination of type-I, type-II and triplet-triplet energy transfer mechanism contribution

scientific article

Artifacts associated with the measurement of oxidized DNA bases.

scientific article

Ascorbate and H2O2 induced oxidative DNA damage in Jurkat cells.

scientific article

Assessment of oxidative base damage to isolated and cellular DNA by HPLC-MS/MS measurement

scientific article

COST Action CM1201 "Biomimetic Radical Chemistry": free radical chemistry successfully meets many disciplines.

scientific article

Cadmium and T cell differentiation: limited impact in vivo but significant toxicity in fetal thymus organ culture.

scientific article published on 7 June 2007

Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up.

scientific article

Characterization of lysine-guanine cross-links upon one-electron oxidation of a guanine-containing oligonucleotide in the presence of a trilysine peptide

scientific article published on 01 May 2006

Chemical quenching of singlet oxygen by carotenoids in plants

scientific article published on 10 January 2012

Chlorination of guanosine and other nucleosides by hypochlorous acid and myeloperoxidase of activated human neutrophils. Catalysis by nicotine and trimethylamine

scientific article

Chromatographic methods for the analysis of oxidatively damaged DNA.

scientific article published on 22 February 2012

Comparison of gadolinium nanoparticles and molecular contrast agents for radiation therapy-enhancement.

scientific article published on 8 September 2017

Cross-linked thymine-purine base tandem lesions: synthesis, characterization, and measurement in gamma-irradiated isolated DNA.

scientific article

DNA binding of the p21 repressor ZBTB2 is inhibited by cytosine hydroxymethylation.

scientific article published on 4 March 2014

DNA-dependent protein kinase (DNA-PK)-deficient human glioblastoma cells are preferentially sensitized by Zebularine.

scientific article

DNA-polyamine cross-links generated upon one electron oxidation of DNA.

scientific article published on 13 May 2014

Depleted uranium induces sex- and tissue-specific methylation patterns in adult zebrafish

scientific article published on 29 January 2016

Design of a synthetic luminescent probe from a biomolecule binding domain: selective detection of AU-rich mRNA sequences

scientific article published on 16 November 2016

Detection of 8-oxoguanine in cellular DNA using 2,6-diamino-8-oxopurine as an internal standard for high-performance liquid chromatography with electrochemical detection

scientific article published on 01 June 1998

Detection of chlorinated DNA and RNA nucleosides by HPLC coupled to tandem mass spectrometry as potential biomarkers of inflammation.

scientific article published on 18 April 2005

Detection of new radiation-induced DNA lesions by liquid chromatography coupled to tandem mass spectrometry

scientific article published on January 2004

Detection of reactive free radicals derived from nucleosides by liquid chromatography coupled to tandem mass spectrometry of DMPO spin trapping adducts

scientific article published on 01 January 2006

Determination of 8-oxoguanine in DNA by gas chromatography--mass spectrometry and HPLC--electrochemical detection: overestimation of the background level of the oxidized base by the gas chromatography--mass spectrometry assay

scientific article published on 01 December 1995

Determination of new types of DNA lesions in human sperm

scientific article published in February 2008

Direct Oxidative Damage of Naked DNA Generated upon Absorption of UV Radiation by Nucleobases

article

Direct and indirect effects of UV radiation on DNA and its components

scientific article

Does vitamin C have a pro-oxidant effect?

Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development

scientific article

Effect of dietary fat-soluble vitamins A and E and proanthocyanidin-rich extract from grape seeds on oxidative DNA damage in rats.

scientific article published on 24 October 2007

Effects of UV and visible radiation on DNA-final base damage

scientific article

Effects of UV and visible radiations on cellular DNA.

scientific article

Effects of subchronic exposure to static magnetic field on testicular function in rats

scientific article published in November 2006

Efficient oxidation and destabilization of Zn(Cys)₄ zinc fingers by singlet oxygen

scientific article published on 07 July 2014

Energy transfer between singlet (1Delta(g)) and triplet (3Sigma(g)-) molecular oxygen in aqueous solution

scientific article published in March 2004

Enhancement of IUdR Radiosensitization by Low-Energy Photons Results from Increased and Persistent DNA Damage

scientific article

Epigenetic, histopathological and transcriptomic effects following exposure to depleted uranium in adult zebrafish and their progeny.

scientific article published on 8 December 2016

Evaluation of DNA adducts, DNA and RNA oxidative lesions, and 3-hydroxybenzo(a)pyrene as biomarkers of DNA damage in lung following intravenous injection of the parent compound in rats.

scientific article published in July 2010

Exercise training combined with antioxidant supplementation prevents the antiproliferative activity of their single treatment in prostate cancer through inhibition of redox adaptation

scientific article published on 16 September 2014

Extranuclear protection of chromosomal DNA from oxidative stress

scientific article

Facts and artifacts in the measurement of oxidative base damage to DNA.

scientific article

First Steps Towards an Understanding of a Mode ofCarcinogenic Action for Vanadium Pentoxide

scientific article (publication date: September 2011)

Formation of modified DNA bases in cells exposed either to gamma radiation or to high-LET particles.

scientific article published in May 2002

Gadolinium nanoparticles and contrast agent as radiation sensitizers.

scientific article published on 19 May 2015

Gas chromatography-mass spectrometry with high-performance liquid chromatography prepurification for monitoring the endonuclease III-mediated excision of 5-hydroxy-5,6-dihydrothymine and 5,6-dihydrothymine from gamma-irradiated DNA.

scientific article

Genotoxicity of combined exposure to polycyclic aromatic hydrocarbons and UVA--a mechanistic study

scientific article published on 24 April 2008

Green autofluorescence, a double edged monitoring tool for bacterial growth and activity in micro-plates.

scientific article published on 10 December 2015

HO* radicals induce an unexpected high proportion of tandem base lesions refractory to repair by DNA glycosylases.

scientific article

High-performance liquid chromatography--tandem mass spectrometry measurement of radiation-induced base damage to isolated and cellular DNA.

scientific article

Hydrogen peroxide causes greater oxidation in cellular RNA than in DNA.

scientific article

Hydroxyl radicals and DNA base damage

scientific article

Identification of the main oxidation products of 8-methoxy-2'-deoxyguanosine by singlet molecular oxygen.

scientific article published in June 2005

Impact of nanoparticles on DNA repair processes: current knowledge and working hypotheses

scientific article

Influence of a static magnetic field (250 mT) on the antioxidant response and DNA integrity in THP1 cells

article

Influence of static magnetic field on cadmium toxicity: Study of oxidative stress and DNA damage in rat tissues

article

Influence of the metabolic properties of human cells on the kinetic of formation of the major benzo[a]pyrene DNA adducts

scientific article

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

scientific article published on 6 July 2011

Intracerebral delivery of carboplatin in combination with either 6 MV photons or monoenergetic synchrotron X-rays are equally efficacious for treatment of the F98 rat glioma

scientific article published on 20 September 2012

Ionizing radiation biomarkers in epidemiological studies - An update

scientific article

Irradiation in presence of iodinated contrast agent results in radiosensitization of endothelial cells: consequences for computed tomography therapy.

scientific article published in August 2005

Isolation and characterization of a new product produced by ionizing irradiation and type I photosensitization of 2'-deoxyguanosine in oxygen-saturated aqueous solution: (2S)-2,5'-ANHYDRO-1-(2'-deoxy-beta-D-erythro-pentofuranosyl)-5-guanidin ylidene

scientific article published on June 1993

Isotope dilution high-performance liquid chromatography-electrospray tandem mass spectrometry assay for the measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine in biological samples

scientific article published on 01 September 1998

Light-induced acclimation of the Arabidopsis chlorina1 mutant to singlet oxygen.

scientific article published on 16 April 2013

Low doses of gamma-irradiation induce an early bystander effect in zebrafish cells which is sufficient to radioprotect cells

scientific article

Measurement of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 8-oxo-7,8-dihydroguanine in isolated DNA exposed to gamma radiation in aqueous solution.

scientific article published in December 1997

Measurement of DNA base damage in cells exposed to low doses of gamma-radiation: comparison between the HPLC-EC and comet assays

scientific article published on 01 January 1999

Measurement of oxidatively generated base damage in cellular DNA.

scientific article

Measurement of the main photooxidation products of 2'-deoxyguanosine using chromatographic methods coupled to mass spectrometry

scientific article

Mechanistic aspects of the oxidation of DNA constituents mediated by singlet molecular oxygen

scientific article published in March 2004

Minor contribution of direct ionization to DNA base damage inducedby heavy ions.

scientific article published in February 2006

Molecular Dynamics Insights into Polyamine-DNA Binding Modes: Implications for Cross-Link Selectivity.

scientific article published on 16 August 2017

N(6)-Methyldeoxyadenosine, a nucleoside commonly found in prokaryotes, induces C2C12 myogenic differentiation.

scientific article published on February 2004

N6-methyladenine: the other methylated base of DNA

scientific article

Natural variability and modulation by environmental stressors of global genomic cytosine methylation levels in a freshwater crustacean, Gammarus fossarum

scientific article published on 02 October 2018

Near diffusion-controlled reaction of a Zn(Cys)4 zinc finger with hypochlorous acid

scientific article published on 26 May 2016

Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster

scientific article published on 27 June 2017

Novel properties of melanins include promotion of DNA strand breaks, impairment of repair, and reduced ability to damage DNA after quenching of singlet oxygen

scientific article published on 6 March 2012

Nuclear magnetic resonance studies of the 4R and 4S diastereomers of spiroiminodihydantoin 2'-deoxyribonucleosides: absolute configuration and conformational features

scientific article published on 01 October 2006

One-electron oxidation of DNA and inflammation processes

scientific article published on 01 July 2006

One-electron oxidation of the guanine moiety of 2'-deoxyguanosine: influence of 8-oxo-7,8-dihydro-2'-deoxyguanosine

scientific article published in February 2003

Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion.

scholarly article

Oxidative DNA Damage and Repair in the Radioresistant Archaeon Thermococcus gammatolerans.

scientific article

Oxidative base damage to DNA: specificity of base excision repair enzymes.

scientific article

Oxidative damage to DNA: formation, measurement and biochemical features.

scientific article published on October 2003

Oxidative damage to DNA: formation, measurement, and biological significance.

scientific article published on January 1997

Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines

scientific article published on 14 January 2011

Oxidative stress, inflammation, and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter

scientific article published on 23 September 2010

Oxidatively generated DNA lesions as potential biomarkers of in vivo oxidative stress

scientific article published on July 2012

Oxidatively generated base damage to cellular DNA.

scientific article

Oxidatively generated complex DNA damage: tandem and clustered lesions.

scientific article published on 25 April 2012

Oxidatively generated damage to cellular DNA by UVB and UVA radiation

scientific article

Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells

scientific article published on 31 July 2008

Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes

Photoactivation of gold nanoparticles for glioma treatment

scientific article published on May 2013

Photobiological activities of 1,6-dioxapyrene in pro- and eukaryotic cells

scientific article published on June 1993

Photoinduced damage to cellular DNA: direct and photosensitized reactions.

scientific article published on 30 August 2012

Photooxidation of d(TpG) by phthalocyanines and riboflavin. Isolation and characterization of dinucleoside monophosphates containing the 4R* and 4S* diastereoisomers of 4,8-dihydro-4-hydroxy-8-oxo-2'-deoxy-guanosine

scientific article published on September 1992

Photosensitization of DNA damage by a new cationic pyropheophorbide derivative: sequence-specific formation of a frank scission.

scientific article

Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis

scientific article published on 10 April 2007

Probing the reactivity of singlet oxygen with purines

scientific article

Protective effects of antioxidants against UVA-induced DNA damage in human skin fibroblasts in culture

scientific article published on 01 October 1998

Radiation Dose-Enhancement Is a Potent Radiotherapeutic Effect of Rare-Earth Composite Nanoscintillators in Preclinical Models of Glioblastoma

scientific article published on 07 September 2020

Radiation-induced DNA damage: formation, measurement, and biochemical features

scientific article published on January 2004

Radiation-induced formation of purine 5',8-cyclonucleosides in isolated and cellular DNA: high stereospecificity and modulating effect of oxygen.

scientific article published on 25 May 2010

Radiation-mediated formation of complex damage to DNA: a chemical aspect overview.

scientific article published on March 2014

Reaction of singlet oxygen with 2'-deoxyguanosine and DNA. Isolation and characterization of the main oxidation products.

scientific article published in April 1995

Recent aspects of oxidative DNA damage: guanine lesions, measurement and substrate specificity of DNA repair glycosylases

scientific article

Redox Behavior of the S-Adenosylmethionine (SAM)-Binding Fe-S Cluster in Methylthiotransferase RimO, toward Understanding Dual SAM Activity

scientific article published on 28 September 2016

Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures

scientific article

Repair and mutagenic potential of oxaluric acid, a major product of singlet oxygen-mediated oxidation of 8-oxo-7,8-dihydroguanine.

scientific article

Riboflavin and UV-light based pathogen reduction: extent and consequence of DNA damage at the molecular level.

scientific article

Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation.

scientific article published on 15 June 2009

Simultaneous determination of five oxidative DNA lesions in human urine

scientific article

Singlet Oxygen Attack on Guanine: Reactivity and Structural Signature within the B-DNA Helix.

scientific article published on 21 July 2016

Singlet oxygen induces oxidation of cellular DNA.

scientific article published on December 2000

Singlet oxygen induces oxidation of cellular DNA.

scientific article published in February 2001

Singlet oxygen oxidation of isolated and cellular DNA: product formation and mechanistic insights.

scientific article published on September 2006

Singlet oxygen-mediated damage to cellular DNA determined by the comet assay associated with DNA repair enzymes

scientific article published in January 2004

Solid-phase synthesis of branched oligonucleotides containing a biologically relevant dCyd341 interstrand crosslink DNA lesion

scientific article published on 01 March 2020

Spiroiminodihydantoin nucleoside formation from 2'-deoxyguanosine oxidation by [(18)O-labeled] singlet molecular oxygen in aqueous solution.

scientific article published in October 2007

Stress-induced DNA damage biomarkers: applications and limitations.

scientific article published on 2 June 2015

Structural and functional characterization of 2-oxo-histidine in oxidized PerR protein

scientific article

Supramolecular cationic tetraruthenated porphyrin and light-induced decomposition of 2'-deoxyguanosine predominantly via a singlet oxygen-mediated mechanism.

scientific article published in November 1998

TARGETED AND OFF-TARGET (BYSTANDER AND ABSCOPAL) EFFECTS OF RADIATION THERAPY: REDOX MECHANISMS AND RISK-BENEFIT ANALYSIS.

scientific article published on 19 January 2018

Targeting G-Rich DNA Structures with Photoreactive Bis-Cyclometallated Iridium(III) Complexes

scientific article published on 29 August 2019

TtcA a new tRNA-thioltransferase with an Fe-S cluster.

scientific article published on 9 June 2014

Undetectable levels of N6-methyl adenine in mouse DNA: Cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine methyltransferase

article

Urinary excretion of 5-(hydroxymethyl) uracil in healthy volunteers: effect of active and passive tobacco smoke

scientific article published on 01 July 1998

Urinary levels of oxidative DNA and RNA damage among workers exposed to polycyclic aromatic hydrocarbons in silicon production: comparison with 1-hydroxypyrene.

scientific article

Zinc supplementation ameliorates static magnetic field-induced oxidative stress in rat tissues

scientific article published on 9 September 2006

[14] Singlet oxygen DNA damage products: Formation and measurement

article

[18O]-labeled singlet oxygen as a tool for mechanistic studies of 8-oxo-7,8-dihydroguanine oxidative damage: detection of spiroiminodihydantoin, imidazolone and oxazolone derivatives.

scientific article published in March 2002

[8] Singlet oxygen DNA damage: Chromatographic and mass spectrometric analysis of damage products

scientific article published in 1994

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