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List of works by Rebecca M. Sappington

Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress.

scientific article

Astrocyte Reactivity: A Biomarker for Retinal Ganglion Cell Health in Retinal Neurodegeneration

scientific article

Constitutive and Stress-induced Expression of CCL5 Machinery in Rodent Retina.

scientific article published on 24 May 2017

Contribution of TRPV1 to microglia-derived IL-6 and NFkappaB translocation with elevated hydrostatic pressure.

scientific article

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

scientific article

Impact of Graphene on the Efficacy of Neuron Culture Substrates

scientific article published on 25 June 2018

Increased bioavailability of cyclic guanylate monophosphate prevents retinal ganglion cell degeneration

scientific article published on 10 September 2018

Interleukin-6 Deficiency Attenuates Retinal Ganglion Cell Axonopathy and Glaucoma-Related Vision Loss.

scientific article

Interleukin-6 protects retinal ganglion cells from pressure-induced death

scientific article published on 01 July 2006

Interleukin-6: A Constitutive Modulator of Glycoprotein 130, Neuroinflammatory and Cell Survival Signaling in Retina.

scientific article published on 22 July 2016

Morphometric changes in the rat optic nerve following short-term intermittent elevations in intraocular pressure.

scientific article

Optic neuropathy due to microbead-induced elevated intraocular pressure in the mouse.

scientific article

Oral Delivery of a Synthetic Sterol Reduces Axonopathy and Inflammation in a Rodent Model of Glaucoma.

scientific article published on 07 February 2017

Pressure-Induced Alterations in PEDF and PEDF-R Expression: Implications for Neuroprotective Signaling in Glaucoma.

scientific article

Pressure-dependent modulation of inward-rectifying K+ channels: implications for cation homeostasis and K+ dynamics in glaucoma

scientific article published on 05 June 2019

Pressure-induced regulation of IL-6 in retinal glial cells: involvement of the ubiquitin/proteasome pathway and NFkappaB.

scientific article

Probing electrical signals in the retina via graphene-integrated microfluidic platforms

scientific article published on 4 November 2016

Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma

scientific article published in March 2006

Retina-on-a-chip: a microfluidic platform for point access signaling studies

scientific article

TRPV1: contribution to retinal ganglion cell apoptosis and increased intracellular Ca2+ with exposure to hydrostatic pressure.

scientific article published on 24 October 2008

The Microbead Occlusion Model of Ocular Hypertension in Mice.

scientific article published in January 2018

The nitric oxide-guanylate cyclase pathway and glaucoma

scientific article published on 01 May 2018

Virus-mediated EpoR76E Therapy Slows Optic Nerve Axonopathy in Experimental Glaucoma.

scientific article published on 27 October 2015