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List of works by Alexander J Ruthenburg

A superhelical spiral in the Escherichia coli DNA gyrase A C-terminal domain imparts unidirectional supercoiling bias.

scientific article

Calibrating ChIP-Seq with Nucleosomal Internal Standards to Measure Histone Modification Density Genome Wide

scientific article published on 21 May 2015

Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq

scientific article published on 10 February 2020

Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription.

scientific article

Does activation of the anti proton, rather than concertedness, determine the stereochemistry of base-catalyzed 1,2-elimination reactions? Anti stereospecificity in E1cB eliminations of β-3-trifluoromethylphenoxy esters, thioesters, and ketones.

scientific article published on 24 February 2012

Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription

scientific article published on 13 July 2020

Facile target validation in an animal model with intracellularly expressed monobodies

scholarly article by Ankit Gupta published in September 2018

Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex

scientific article

Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis

scientific article

Multivalent engagement of chromatin modifications by linked binding modules

scientific article (publication date: December 2007)

Native internally calibrated chromatin immunoprecipitation for quantitative studies of histone post-translational modifications

scientific article published on 13 November 2019

Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase.

scientific article published on 12 August 2005

Quantitative and Structural Assessment of Histone Methyllysine Analogue Engagement by Cognate Binding Proteins Reveals Affinity Decrements Relative to Those of Native Counterparts.

scientific article

Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions

scientific article

Recombinant antibodies to histone post-translational modifications

scientific article

Sequence deeper without sequencing more: Bayesian resolution of ambiguously mapped reads

scientific article published on 19 April 2021

The United States of histone ubiquitylation and methylation

scientific article published on 01 July 2011

Traceless semisynthesis of a set of histone 3 species bearing specific lysine methylation marks.

scientific article published on 22 August 2014

Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm

scientific article published on 27 December 2017

Validation of histone-binding partners by peptide pull-downs and isothermal titration calorimetry

scientific article published on 01 January 2012

WDR76 promotes MLL-rearranged leukemia via selective recognition of 5-hydroxymethylcytosine in DNA