List of works - Ana Cristina Rego

Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts.

scientific article published on 20 May 2014

Adenosine Triphosphate Degradation Products After Oxidative Stress and Metabolic Dysfunction in Cultured Retinal Cells ⬇️

scientific article published on 01 September 1997

Adenosine modulation of d-[3H]aspartate release in cultured retina cells exposed to oxidative stress

scientific article published on 01 March 2000

Alpha-synuclein-induced oxidative stress correlates with altered superoxide dismutase and glutathione synthesis in human neuroblastoma SH-SY5Y cells

scientific article published on 16 July 2016

Alteration of nitric oxide synthase activity upon oxidative stress in cultured retinal cells

scientific article published on 01 March 1998

Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.

scientific article

Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures.

scientific article

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

scientific article published on January 2009

Antioxidant effect of flavonoids after ascorbate/Fe(2+)-induced oxidative stress in cultured retinal cells.

scientific article published in July 2001

Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium release

scientific article published on 6 September 2014

BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.

scientific article published in July 2009

BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons.

scientific article published on 23 June 2009

Bcl-2 prevents loss of cell viability and caspase activation induced by 3-nitropropionic acid in GT1-7 cells.

scientific article published on December 2003

Bioenergetic dysfunction in Huntington's disease human cybrids.

scientific article published on 13 June 2011

Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons.

scientific article published in May 2006

Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

scientific article published on 27 March 2008

Characterization of subventricular zone-derived progenitor cells from mild and late symptomatic YAC128 mouse model of Huntington's disease

scientific article published on 19 September 2017

Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields

scientific article published on 26 April 2019

Compromised mitochondrial complex II in models of Machado-Joseph disease.

scientific article

Current therapeutic advances in patients and experimental models of Huntington's disease.

scientific article published on March 2014

Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

scientific article

Disclosing the functional changes of two genetic alterations in a patient with Chronic Progressive External Ophthalmoplegia: Report of the novel mtDNA m.7486G>A variant.

scientific article published on 23 November 2017

Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells

scientific article

Dual Effect of Lipid Peroxidation on the Membrane Order of Retinal Cells in Culture

article

Dysfunctional synapse in Alzheimer's disease - A focus on NMDA receptors.

scientific article published on 22 August 2013

Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

scientific article

Effect of chronic exposure to aluminium on isoform expression and activity of rat (Na+/K+)ATPase.

scientific article

Effect of glucose deprivation and acute glutamate exposure in cultured retinal cells.

scientific article published in September 1998

Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.

scientific article published on 14 July 2008

FK506 ameliorates cell death features in Huntington's disease striatal cell models.

scientific article published on 15 June 2011

Glutamate-mediated inhibition of oxidative phosphorylation in cultured retinal cells

scientific article published on 01 February 2000

Glutathione redox cycle dysregulation in Huntington's disease knock-in striatal cells.

scientific article published on 14 September 2012

Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease.

scientific article published on 25 January 2017

IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice.

scientific article published on 18 December 2013

IGF-1 protects against diabetic features in an in vivo model of Huntington's disease.

scientific article

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.

scientific article published on 13 August 2014

Impaired transcription in Alzheimer's disease: key role in mitochondrial dysfunction and oxidative stress.

scientific article published on January 2013

Influence of gamma-aminobutyric acid on retinal cells excitotoxicity upon glucose deprivation.

scientific article published in May 1999

Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress

scientific article published on 01 June 1999

Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin.

scientific article published on 03 February 2016

Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

scientific article

Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.

scientific article published in October 2006

Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

scientific article

Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells

scientific article

Mechanisms of neurodegeneration in Huntington's disease.

scientific article published on June 2008

Mitochondrial Ca2+ handling in Huntington's and Alzheimer's diseases - Role of ER-mitochondria crosstalk.

scientific article

Mitochondrial Dysfunction in Huntington's Disease

scientific article published in January 2018

Mitochondrial and metabolic-based protective strategies in Huntington’s disease: the case of creatine and coenzyme Q ⬇️

scientific article published on 02 December 2011

Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.

scientific article published in August 2003

Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases ⬇️

scientific article published on October 1, 2003

Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers.

scientific article published on 23 May 2013

Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.

scientific article

Mitochondrial-Associated Metabolic Changes and Neurodegeneration in Huntingtons Disease - from Clinical Features to the Bench ⬇️

scientific article published on October 1, 2010

Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors.

scientific article

Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.

scientific article

Molecular Pathways of Mitochondrial Dysfunction in Neurodegeneration: the Paradigms of Parkinson's and Huntington's Diseases

scholarly article published 2007

Multiple Defects in Energy Metabolism in Alzheimers Disease ⬇️

scientific article published on October 1, 2010

OXPHOS dysfunction regulates integrin-β1 modifications and enhances cell motility and migration.

scientific article published on 11 December 2014

Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease.

scientific article

Oxidative stress in acidic conditions increases the production of inositol phosphates in chick retinal cells in culture

article

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

scientific article published on 6 April 2015

Oxidizing effects of exogenous stressors in Huntington's disease knock-in striatal cells--protective effect of cystamine and creatine

scientific article published on 5 September 2013

Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity.

scientific article published on January 2005

Protective effects of 3-alkyl luteolin derivatives are mediated by Nrf2 transcriptional activity and decreased oxidative stress in Huntington's disease mouse striatal cells

scientific article published on 14 October 2015

Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse.

scientific article

Revisiting Mitochondrial Function and Metabolism in Pluripotent Stem Cells: Where Do We Stand in Neurological Diseases?

scientific article published on 18 February 2016

Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease--resemblance to the effect of amphetamine drugs of abuse.

scientific article published on 25 August 2012

Sirtuins: double players in Huntington's disease

scientific article

Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

scientific article published on 24 March 2017

The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models

scientific article published on 01 April 2021

biomass increases dendritic arborization of newly-generated neurons in mouse hippocampal dentate gyrus

scientific article published on 31 August 2018

List of works by Ana Cristina Rego

Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts.

Adenosine Triphosphate Degradation Products After Oxidative Stress and Metabolic Dysfunction in Cultured Retinal Cells ⬇️

Adenosine modulation of d-[3H]aspartate release in cultured retina cells exposed to oxidative stress

Alpha-synuclein-induced oxidative stress correlates with altered superoxide dismutase and glutathione synthesis in human neuroblastoma SH-SY5Y cells

Alteration of nitric oxide synthase activity upon oxidative stress in cultured retinal cells

Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.

Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures.

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

Antioxidant effect of flavonoids after ascorbate/Fe(2+)-induced oxidative stress in cultured retinal cells.

Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium release

BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype.

BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons.

Bcl-2 prevents loss of cell viability and caspase activation induced by 3-nitropropionic acid in GT1-7 cells.

Bioenergetic dysfunction in Huntington's disease human cybrids.

Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons.

Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

Characterization of subventricular zone-derived progenitor cells from mild and late symptomatic YAC128 mouse model of Huntington's disease

Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields

Compromised mitochondrial complex II in models of Machado-Joseph disease.

Current therapeutic advances in patients and experimental models of Huntington's disease.

Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

Disclosing the functional changes of two genetic alterations in a patient with Chronic Progressive External Ophthalmoplegia: Report of the novel mtDNA m.7486G>A variant.

Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells

Dual Effect of Lipid Peroxidation on the Membrane Order of Retinal Cells in Culture

Dysfunctional synapse in Alzheimer's disease - A focus on NMDA receptors.

Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

Effect of chronic exposure to aluminium on isoform expression and activity of rat (Na+/K+)ATPase.

Effect of glucose deprivation and acute glutamate exposure in cultured retinal cells.

Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.

FK506 ameliorates cell death features in Huntington's disease striatal cell models.

Glutamate-mediated inhibition of oxidative phosphorylation in cultured retinal cells

Glutathione redox cycle dysregulation in Huntington's disease knock-in striatal cells.

Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease.

IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice.

IGF-1 protects against diabetic features in an in vivo model of Huntington's disease.

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.

Impaired transcription in Alzheimer's disease: key role in mitochondrial dysfunction and oxidative stress.

Influence of gamma-aminobutyric acid on retinal cells excitotoxicity upon glucose deprivation.

Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress

Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin.

Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.

Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells

Mechanisms of neurodegeneration in Huntington's disease.

Mitochondrial Ca2+ handling in Huntington's and Alzheimer's diseases - Role of ER-mitochondria crosstalk.

Mitochondrial Dysfunction in Huntington's Disease

Mitochondrial and metabolic-based protective strategies in Huntington’s disease: the case of creatine and coenzyme Q ⬇️

Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.

Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases ⬇️

Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers.

Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.

Mitochondrial-Associated Metabolic Changes and Neurodegeneration in Huntingtons Disease - from Clinical Features to the Bench ⬇️

Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors.

Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.

Molecular Pathways of Mitochondrial Dysfunction in Neurodegeneration: the Paradigms of Parkinson's and Huntington's Diseases

Multiple Defects in Energy Metabolism in Alzheimers Disease ⬇️

OXPHOS dysfunction regulates integrin-β1 modifications and enhances cell motility and migration.

Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease.

Oxidative stress in acidic conditions increases the production of inositol phosphates in chick retinal cells in culture

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

Oxidizing effects of exogenous stressors in Huntington's disease knock-in striatal cells--protective effect of cystamine and creatine

Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity.

Protective effects of 3-alkyl luteolin derivatives are mediated by Nrf2 transcriptional activity and decreased oxidative stress in Huntington's disease mouse striatal cells

Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse.

Revisiting Mitochondrial Function and Metabolism in Pluripotent Stem Cells: Where Do We Stand in Neurological Diseases?

Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease--resemblance to the effect of amphetamine drugs of abuse.

Sirtuins: double players in Huntington's disease

Sodium butyrate rescues dopaminergic cells from alpha-synuclein-induced transcriptional deregulation and DNA damage

The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models

biomass increases dendritic arborization of newly-generated neurons in mouse hippocampal dentate gyrus