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List of works by Guido Franceschini

A 33-year-old man with nephrotic syndrome and lecithin-cholesterol acyltransferase (LCAT) deficiency. Description of two new mutations in the LCAT gene

article

A model structure for the heterodimer apoA-IMilano-apoA-II supports its peculiar susceptibility to proteolysis.

scientific article published on 4 August 2006

Acquired lecithin:cholesterol acyltransferase deficiency as a major factor in lowering plasma HDL levels in chronic kidney disease

scientific article published on 01 August 2014

Activation of Lecithin Cholesterol Acyltransferase by a Disulfide-Linked Apolipoprotein A-I Dimer

scientific article published on 01 March 1997

Activity profile of gemfibrozil on the major plasma lipoprotein parameters

article published in 1992

Alterations in the HDL system after rapid plasma cholesterol reduction by LDL-apheresis

scientific article published on 01 August 1988

An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia

scientific article published in February 2004

Anti-inflammatory and cardioprotective activities of synthetic high-density lipoprotein containing apolipoprotein A-I mimetic peptides

scientific article published on 27 November 2007

Apheretic treatment of severe familial hypercholesterolemia: comparison of dextran sulfate cellulose and double membrane filtration methods for low density lipoprotein removal

scientific article published on 01 October 1988

Apolipoprotein A-II modulates HDL remodeling in plasma

scientific article published on 01 March 1992

Apolipoprotein A-IMilano. Detection of normal A-I in affected subjects and evidence for a cysteine for arginine substitution in the variant A-I

scientific article

Apolipoprotein AIMilano. Partial lecithin: Cholesterol acyltransferase deficiency due to low levels of a functional enzyme

scientific article published on 01 March 1990

Apolipoprotein composition and particle size affect HDL degradation by chymase: effect on cellular cholesterol efflux.

scientific article

Association of lipoprotein(a) with atherothrombotic events and fibrinolytic variables. A case-control study

scientific article published on 01 May 1995

Beta2-adrenergic activity modulates vascular tone regulation in lecithin:cholesterol acyltransferase knockout mice.

scientific article

Bezafibrate lowers plasma lipids, fibrinogen and platelet aggregability in hypertriglyceridaemia.

scientific article published on January 1992

CETP levels rather than polymorphisms as markers of coronary risk: Healthy athlete with high HDL-C and coronary disease—effectiveness of probucol

Changes in high-density lipoprotein subfraction distribution and increased cholesteryl ester transfer after probucol

scientific article published on 01 July 1988

Characterization of A-I-containing lipoproteins in subjects with A-I Milano variant

scientific article published on 01 May 1988

Characterization of three kindreds with familial combined hypolipidemia caused by loss-of-function mutations of ANGPTL3.

scientific article

Cholesterol efflux from Fu5AH hepatoma cells induced by plasma of subjects with or without coronary artery disease and non-insulin-dependent diabetes: importance of LpA-I:A-II particles and phospholipid transfer protein

scientific article published on 01 December 1996

Cholesterol synthesis inhibitors do not reduce Lp(a) levels in normocholesterolemic patients.

scientific article

Cimetidine increases HDL-cholesterol, particularly in the HDL3 subfraction

Clinical Evaluation of Probucol in Hypercholesterolemia: Individual Lipoprotein Responses and Inhibitory Effect on Carotid Atherosclerosis Progression

article

Comparison of the lipoprotein and hemostatic changes after a triphasic and a monophasic low dose oral contraceptive in premenopausal middle-aged women

scientific article published on 01 October 1990

Denaturation and Self-Association of Apolipoprotein A-I Investigated by Electrophoretic Techniques

scientific article published on 01 June 1997

Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein

scientific article published on 29 December 2003

Differential effects of fenofibrate and extended-release niacin on high-density lipoprotein particle size distribution and cholesterol efflux capacity in dyslipidemic patients

scientific article

Distant homology modeling of LCAT and its validation through in silico targeting and in vitro and in vivo assays

scientific article

Dose-related increase of HDL-cholesterol levels after N-acetylcysteine in man

scientific article published on 01 October 1993

Drug control of reverse cholesterol transport.

scientific article published on January 1994

Effect of gemfibrozil treatment in hypercholesterolemia on low density lipoprotein (LDL) subclass distribution and LDL-cell interaction

scientific article published on 01 April 1995

Effects of established hypolipidemic drugs on HDL concentration, subclass distribution, and function

scientific article

Effects of fenofibrate and simvastatin on HDL-related biomarkers in low-HDL patients

scientific article published on 15 November 2006

Effects of probucol on the high density lipoprotein system in hypercholesterolaemic patients

scientific article published on 01 January 1989

Elevated soluble cellular adhesion molecules in subjects with low HDL-cholesterol.

scientific article

Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein A-IMilano

scientific article published on 01 January 1998

Endogenous hypertriglyceridemia in a nonobese rat model: plasma lipoproteins and dietary sensitivity

scientific article published on 01 May 1986

Endothelial protection by high-density lipoproteins: from bench to bedside

scientific article

Enzymatically Active Paraoxonase-1 Is Located at the External Membrane of Producing Cells and Released by a High Affinity, Saturable, Desorption Mechanism

scientific article published in Journal of Biological Chemistry

Familial associations of lipids and lipoproteins in a highly consanguineous population: the Limone sul Garda study

scientific article published on 01 March 1985

Familial disorders of plasma apolipoproteins

scientific article published on 01 June 1985

Fenofibrate and extended-release niacin improve the endothelial protective effects of HDL in patients with metabolic syndrome.

scientific article

Functional LCAT is not required for macrophage cholesterol efflux to human serum

scientific article

Gene dose of the epsilon 4 allele of apolipoprotein E and disease progression in sporadic late-onset Alzheimer's disease.

scientific article

Genetic determinants of HDL metabolism

scientific article published on January 2014

Genetic lecithin:cholesterol acyltransferase deficiency and cardiovascular disease ⬇️

scientific article published on November 28, 2011

HDL and atherosclerosis: Insights from inherited HDL disorders.

scientific article

High-density lipoprotein quantity or quality for cardiovascular prevention?

scientific article published on May 2010

High-density lipoproteins attenuate interleukin-6 production in endothelial cells exposed to pro-inflammatory stimuli

article

High-density lipoproteins protect isolated rat hearts from ischemia-reperfusion injury by reducing cardiac tumor necrosis factor-alpha content and enhancing prostaglandin release

scientific article published in February 2003

Human apolipoprotein A-II inhibits the formation of pre-β high density lipoproteins

scientific article published on 01 November 1996

In vitro activity of probucol on cholesteryl ester transport

scientific article published on 01 August 1990

Increased affinity of LDL for their receptors after acipimox treatment in hypertriglyceridemia

scientific article published on 01 January 1991

Increased carotid artery intima-media thickness in subjects with primary hypoalphalipoproteinemia

scientific article published in February 2002

Increased plasma and aortic triglycerides in rabbits after acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific article published on 01 August 1984

Increased total and high density lipoprotein cholesterol with apoprotein changes resembling streptozotocin diabetes in tetrachlorodibenzodioxin (TCDD) treated rats.

scientific article published in March 1980

Inflammation impairs eNOS activation by HDL in patients with acute coronary syndrome.

scientific article published on 28 June 2013

Influence of bezafibrate, fenofibrate, nicotinic acid and etofibrate on plasma high-density lipoprotein levels

scientific article published on 01 August 1983

Influence of serum triglycerides on the HDL pattern in normal subjects and patients with coronary artery disease.

scientific article published on September 1990

Inhibition of VCAM-1 Expression in Endothelial Cells by Reconstituted High Density Lipoproteins

scientific article published on 01 September 1997

Lecithin:cholesterol acyltransferase, high-density lipoproteins, and atheroprotection in humans.

scientific article published on February 2010

Lipoprotein changes and increased affinity of LDL for their receptors after acipimox treatment in hypertriglyceridemia

scientific article published on 01 February 1990

Mast cell chymase degrades apoE and apoA-II in apoA-I-knockout mouse plasma and reduces its ability to promote cellular cholesterol efflux

scientific article (publication date: September 2002)

Mechanisms of high-density lipoprotein reduction after probucol treatment: Changes in plasma cholesterol esterification/transfer and lipase-activities

scientific article published on 01 February 1993

Metabolism of apolipoproteins AI and AII in subjects carrying similar apoAI mutations, apoAI Milano and apoAI Paris

scientific article published on 01 February 2000

Microporous cholestyramine in suspension form

scientific article published on 01 August 1982

Modulated serum activities and concentrations of paraoxonase in high density lipoprotein deficiency states.

scientific article published in July 1998

Normal vascular function despite low levels of high-density lipoprotein cholesterol in carriers of the apolipoprotein A-I(Milano) mutant

scientific article published on 22 October 2007

Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia

scientific article

Off-target effects of thrombolytic drugs: apolipoprotein A-I proteolysis by alteplase and tenecteplase

scientific article published on 05 December 2012

Omacor in familial combined hyperlipidemia: effects on lipids and low density lipoprotein subclasses

scientific article published on 01 February 2000

Pantethine reduces plasma cholesterol and the severity of arterial lesions in experimental hypercholesterolemic rabbits

scientific article published on 01 December 1984

Pharmacological control of hypertriglyceridemia.

scientific article

Pharmacological studies on tiadenol in type IV patients. Evidence for a mechanism of action different from other lipid-lowering drugs

scientific article published on 01 November 1981

Plasma lecithin:cholesterol acyltransferase and carotid intima-media thickness in European individuals at high cardiovascular risk

scientific article

Plasma triglycerides and lipoprotein(a): inverse relationship in a hyperlipidemic Italian population

scientific article published on 01 July 1993

Recombinant apolipoprotein A-I(Milano) infusion into rabbit carotid artery rapidly removes lipid from fatty streaks.

scientific article

Recombinant apolipoprotein A-IMilano for the treatment of cardiovascular diseases.

scientific article

Recombinant apolipoproteins for the treatment of vascular diseases

scientific article published on 01 January 1999

Recombinant human LCAT normalizes plasma lipoprotein profile in LCAT deficiency.

scientific article

Relation between the HDL apoproteins and AI isoproteins in subjects with the AIMilano abnormality

scientific article

Relationship of the phenotypic expression of the A-IMilano apoprotein with plasma lipid and lipoprotein patterns

scientific article published on 01 December 1985

Role of LCAT in HDL remodeling: investigation of LCAT deficiency states

scientific article published on 20 December 2006

Severe High-Density Lipoprotein Deficiency Associated With Autoantibodies Against Lecithin:Cholesterol Acyltransferase in Non-Hodgkin Lymphoma

scientific article published on 01 January 2012

Structural and dynamic features of apolipoprotein A-I cysteine mutants, Milano and Paris, in synthetic HDL.

scientific article published on 20 August 2010

Structure and function of the apoA-IV T347S and Q360H common variants

scientific article

Synthetic high density lipoproteins for the treatment of myocardial ischemia/reperfusion injury.

scientific article published on September 2006

The C-terminal domain of apolipoprotein A-I is involved in ABCA1-driven phospholipid and cholesterol efflux.

scientific article published on December 2002

The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families

scientific article

The molecular structure of apolipoprotein A-II modulates the capacity of HDL to promote cell cholesterol efflux

scientific article published on 01 January 1996

The plasma concentration of Lpa-I:A-II particles as a predictor of the inflammatory response in patients with ST-elevation myocardial infarction.

scientific article published on 12 April 2008

Therapy with HMG CoA reductase inhibitors: characteristics of the long-term permanence of hypocholesterolemic activity

scientific article published on 01 October 1995

Tolerability of fibric acids. Comparative data and biochemical bases.

scientific article

Vascular alterations in apolipoprotein A-I amyloidosis (Leu75Pro). A case-control study.

scientific article published on 21 July 2015

eNOS activation by HDL is impaired in genetic CETP deficiency.

scientific article

ω-3 Fatty acids selectively raise high-density lipoprotein 2 levels in healthy volunteers

scientific article published on 01 December 1991

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