Search filters

List of works by Eduardo Henrique Silva Sousa

A Potential Visible-Light NO Releaser: Synthesis, Reactivity and Vasodilator Properties

scholarly article by Aurideia de Sousa et al published 2017 in Journal of the Brazilian Chemical Society

A bioinorganic chemistry perspective on the roles of metals as drugs and targets against Mycobacterium tuberculosis - a journey of opportunities

scientific article published on 25 June 2020

A memory of oxygen binding explains the dose response of the heme-based sensor FixL.

scientific article published on 8 May 2007

A proximal arginine R206 participates in switching of the Bradyrhizobium japonicum FixL oxygen sensor.

scientific article

A spectroelectrochemical investigation of the heme-based sensor DevS from Mycobacterium tuberculosis: a redox versus oxygen sensor

scientific article published on 11 July 2019

A vanillin-based copper(ii) metal complex with a DNA-mediated apoptotic activity

scholarly article in RSC Advances, vol. 8 no. 30, 2018

Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection

scientific article published on 27 June 2012

An inorganic iron complex that inhibits wild-type and an isoniazid-resistant mutant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis.

scientific article

An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control.

scientific article published in October 2009

Anti-asthmatic effect of nitric oxide metallo-donor FOR811A [cis-[Ru(bpy)2(2-MIM)(NO)](PF6)3] in the respiratory mechanics of Swiss mice

scientific article published on 12 March 2021

Antimicrobial activity and antibiotic synergy of a biphosphinic ruthenium complex against clinically relevant bacteria

scientific article published on 25 May 2020

Aryl-Substituted Ruthenium(II) Complexes: A Strategy for Enhanced Photocleavage and Efficient DNA Binding

scientific article published on 20 July 2017

Ascorbyl and hydroxyl radical generation mediated by a copper complex adsorbed on gold

scientific article published on 09 September 2019

Asymmetric heterobimetallic mixed-valence complex trans-[(SO3)Co(cyclam)(NCS)Ru(NH3)4(NCS)](BF4): Synthesis and characterization

Development of a spectrophotometric assay for cyclase activity.

scientific article

DosT and DevS are oxygen-switched kinases in Mycobacterium tuberculosis

scientific journal article

Drug discovery targeting heme-based sensors and their coupled activities

scientific article published on 20 November 2016

Effect of Crotalus basiliscus snake venom on the redox reaction of myoglobin

scientific article published on 23 January 2019

Electrochemical, mechanistic, and DFT studies of amine derived diphosphines containing Ru(II)-cymene complexes with potent in vitro cytotoxic activity against HeLa and triple-negative breast cancer cells MDA-MB-231

scientific article published on 18 November 2020

Electrochemistry, surface plasmon resonance, and quartz crystal microbalance: an associative study on cytochrome c adsorption on pyridine tail-group monolayers on gold.

scientific article published on 16 July 2013

Escherichia coli DosC and DosP: a role of c-di-GMP in compartmentalized sensing by degradosomes

scientific article published on 12 July 2019

Haem-Based Sensors of O2: Lessons and Perspectives.

scientific article published on 6 July 2017

Hell's Gate globin I: an acid and thermostable bacterial hemoglobin resembling mammalian neuroglobin

scientific article

Hydroxyl Radical Generation and DNA Nuclease Activity: A Mechanistic Study Based on a Surface-Immobilized Copper Thioether Clip-Phen Derivative

scientific article published on 16 June 2016

In vitro and in vivo leishmanicidal activity of a ruthenium nitrosyl complex against Leishmania (Viannia) braziliensis

scientific article published on 25 January 2019

Incorporation of Nitroprusside on Silica Nanoparticles-A Strategy for Safer Use of This NO Donor in Therapy

scientific article published on 24 May 2019

Insights into signal transduction by a hybrid FixL: Denaturation study of on and off states of a multi-domain oxygen sensor.

scientific article published on 13 April 2017

Is IQG-607 a Potential Metallodrug or Metallopro-Drug With a Defined Molecular Target in Mycobacterium tuberculosis?

scientific article

Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design.

scientific article published on 28 September 2011

Mechanism and biological implications of the NO release of cis-[Ru(bpy)2L(NO)](n+) complexes: a key role of physiological thiols

scientific article published on 19 February 2011

Nitro-imidazole-based ruthenium complexes with antioxidant and anti-inflammatory activities

scientific article published on 24 February 2020

Oxygen triggers signal transduction in the DevS (DosS) sensor of Mycobacterium tuberculosis by modulating the quaternary structure

scientific article published on 16 January 2019

Oxygen-sensing histidine-protein kinases: assays of ligand binding and turnover of response-regulator substrates.

scientific article published on January 2008

Photochemical studies of cis-[Ru(bpy)2(4-bzpy)(CO)](PF6)2 and cis-[Ru(bpy)2(4-bzpy)(Cl)](PF6): Blue light-induced nucleobase binding.

scientific article published on 15 May 2017

Potential therapeutic approaches for a sleeping pathogen: tuberculosis a case for bioinorganic chemistry

scientific article published on 16 July 2020

Preparation, characterization and structure of ruthenium phosphine complexes containing non-innocent ligands

Relaxant effect of a metal-based drug in human corpora cavernosa and its mechanism of action

scientific article

Signal transduction and phosphoryl transfer by a FixL hybrid kinase with low oxygen affinity: importance of the vicinal PAS domain and receiver aspartate.

scientific article

Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex.

scientific article published on January 2006

Structural aspects and physiological implications of the hemoglobin of green iguana (Iguana iguana)

scientific article published on 29 August 2018

Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy.

scientific article published on 21 November 2017

Target DNA stabilizes Mycobacterium tuberculosis DevR/DosR phosphorylation by the full-length oxygen sensors DevS/DosS and DosT.

scientific article published on 4 October 2017

The Heme-Based Oxygen Sensor Rhizobium etli FixL: Influence of Auxiliary Ligands on Heme Redox Potential and Implications on the Enzyme Activity.

scientific article published on 26 August 2016

The nitric oxide donor cis-[Ru(bpy)2(SO3)NO](PF6) increases gastric mucosa protection in mice--involvement of the soluble guanylate cyclase/K(ATP) pathway

scientific article published on 11 February 2015

The potent anti-cancer activity of Dioclea lasiocarpa lectin

scientific article

The ruthenium NO donor, [Ru(bpy)2(NO)SO3](PF6), inhibits inflammatory pain: involvement of TRPV1 and cGMP/PKG/ATP-sensitive potassium channel signaling pathway

scientific article published on 5 March 2013

Thiocarbonyl-bound metallonitrosyl complexes with visible-light induced DNA cleavage and promising vasodilation activity

scientific article published on 9 February 2018

[Fe(CN)5(isoniazid)](3-): an iron isoniazid complex with redox behavior implicated in tuberculosis therapy

scientific article published on 12 August 2014

Paulina is supported by:

About Paulina

Help