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List of works by David Sumpton

2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer

scientific article published on 19 May 2020

Blebs produced by actin-myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs

scientific article

Cell fate decisions are specified by the dynamic ERK interactome

scientific article

Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates

scientific article published on 14 February 2019

Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress

scientific article published on 2 March 2018

Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features

scientific article

Coomassie stains: are they really mass spectrometry compatible?

scientific article

D-mannose suppresses macrophage IL-1β production

scientific article published on 11 December 2020

Formate induces a metabolic switch in nucleotide and energy metabolism

scientific article published on 04 May 2020

Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells.

scientific article published on 21 December 2017

Identification of novel PCTAIRE-1/CDK16 substrates using a chemical genetic screen

scientific article published on 14 March 2019

Impact of Formate Supplementation on Body Weight and Plasma Amino Acids

scientific article published on 22 July 2020

Improving the metabolic fidelity of cancer models with a physiological cell culture medium

article

Increased formate overflow is a hallmark of oxidative cancer.

scientific article

Influence of various endogenous and artefact modifications on large-scale proteomics analysis

scientific article published in February 2013

Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate

scientific article published on 13 February 2015

Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels ⬇️

scientific article published in Nature Communications

Nodulation gene mutants of Mesorhizobium loti R7A-nodZ and nolL mutants have host-specific phenotypes on Lotus spp.

scientific article

NopM and NopD are rhizobial nodulation outer proteins: identification using LC-MALDI and LC-ESI with a monolithic capillary column.

scientific article

Polarized cell motility induces hydrogen peroxide to inhibit cofilin via cysteine oxidation

scientific article published on 14 May 2015

Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarinoma Invasion and Tumor Growth.

scientific article published on 18 April 2018

Sinorhizobium fredii HH103 cgs mutants are unable to nodulate determinate- and indeterminate nodule-forming legumes and overproduce an altered EPS.

scientific article

Src activation by Chk1 promotes actin patch formation and prevents chromatin bridge breakage in cytokinesis

scientific article published on 28 June 2018

Stratification of cancer and diabetes based on circulating levels of formate and glucose

scientific article published on 24 April 2019

Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases

scientific article published on 18 September 2020

THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer

scientific article published on 11 January 2022

Targeting the Metabolic Response to Statin-Mediated Oxidative Stress Produces a Synergistic Antitumor Response

scientific article published on 27 September 2019

The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis

scientific article published on 2 March 2016

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

scientific article published on 07 January 2021

The dioxygenase-encoding olsD gene from Burkholderia cenocepacia causes the hydroxylation of the amide-linked fatty acyl moiety of ornithine-containing membrane lipids.

scientific article published on 5 July 2011

The pathogenesis of mesothelioma is driven by a dysregulated translatome

scientific article published on 13 August 2021

Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition

scientific article published on 13 August 2020

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