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List of works by Ivan Maillard

A Snail1/Notch1 signalling axis controls embryonic vascular development.

scientific article

A jagged road to lymphoma aggressiveness.

scientific article published on March 2014

A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance

scientific article

ADAM10 regulates Notch function in intestinal stem cells of mice

scientific article

Absence of a red blood cell phenotype in mice with hematopoietic deficiency of SEC23B.

scientific article

An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD.

scientific article published on 29 August 2017

An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling

scientific article

Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells

scientific article published on 13 April 2015

BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells

scientific article published on 23 February 2017

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

scientific article published on April 2013

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis

scientific article

Can genetics resolve what Notch does in HSCs?

scientific article

Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells

scientific article published on April 2008

Closer to the source: notch and the nature of thymus-settling cells.

scientific article

Compartmentalized effects of aging on group 2 innate lymphoid cell development and function

scientific article published on 20 August 2019

Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.

scientific article published on 22 May 2015

Cutting Edge: Notch Signaling Promotes the Plasticity of Group-2 Innate Lymphoid Cells.

scientific article published on 23 January 2017

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

scientific article published on 03 October 2019

Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4+ T Cells in Graft-versus-Host Disease

scientific article published on 10 June 2019

Epithelial Notch signaling is a limiting step for pancreatic carcinogenesis.

scientific article

Fetal hematopoietic stem cells are making waves.

scientific article published on 7 April 2017

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

scientific article published on 20 March 2017

From the cradle to the grave: activities of GATA‐3 throughout T‐cell development and differentiation ⬇️

scientific article published on November 1, 2010

From the yolk sac to the spleen: New roles for Notch in regulating hematopoiesis

scientific article published on 01 May 2003

Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma.

scientific article

GATA-3 is required for early T lineage progenitor development

scientific journal article

GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion.

scientific article

GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells

scientific article published on 14 February 2020

Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades.

scientific article

Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation

scientific article published on 09 December 2013

Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1.

scientific article

IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

article

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

scientific article

Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V(beta) domains.

scientific article

Ikaros, Notch, and GATA1 cross paths during megakaryopoiesis.

scientific article published in March 2013

Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease ⬇️

scientific article published on April 6, 2011

Immunology. Keeping a tight leash on Notch.

scientific article

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

scientific article

Increased expression of PcG protein YY1 negatively regulates B cell development while allowing accumulation of myeloid cells and LT-HSC cells

scientific article (publication date: 2012)

Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration

scientific article

MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis

scientific article published on 03 May 2018

MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.

scientific article published on 30 July 2013

MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function.

scientific article published on February 2012

Mastermind critically regulates Notch-mediated lymphoid cell fate decisions.

scientific article published on 8 June 2004

Metabolism: Inflammation keeps old mice healthy.

scientific article published on 18 November 2015

New Insights into Graft-Versus-Host Disease and Graft Rejection

scientific article published on 3 November 2017

Notch Ligand Delta-like 4 Promotes Regulatory T Cell Identity in Pulmonary Viral Infection

scientific article published on 11 January 2017

Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing.

scientific article

Notch Signaling Promotes Mature T-Cell Lymphomagenesis

scientific article published in 2022

Notch Signaling and Alloreactivity.

scientific article published on 8 September 2016

Notch activity synergizes with B-cell-receptor and CD40 signaling to enhance B-cell activation

scientific article published on 19 December 2006

Notch and cancer: best to avoid the ups and downs.

scientific article

Notch and human hematopoietic stem cells

scientific article published on February 2014

Notch and the immune system

scientific article published on 01 December 2003

Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation.

scientific article

Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection

scientific article published on 23 July 2018

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

scientific article published on 26 February 2013

Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration

scientific article published on 30 March 2015

Notch signaling and development of the hematopoietic system.

scientific article published on January 2012

Notch signaling at the crossroads of innate and adaptive immunity

scientific article published on 18 June 2020

Notch signaling in cancer

scientific article

Notch signaling in hematopoietic cell transplantation and T cell alloimmunity.

scientific article published on 31 August 2013

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

scientific article

Notch signaling is an important regulator of type 2 immunity.

scientific article

Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice

scientific article published on 04 September 2018

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.

scientific article published on 21 December 2011

Notch signaling regulates T cell accumulation and function in the central nervous system during experimental autoimmune encephalomyelitis.

scientific article published on 03 July 2013

Notch signaling specifies megakaryocyte development from hematopoietic stem cells.

scientific article published on September 2008

Notch signalling in T cell homeostasis and differentiation

scientific article published on 06 November 2019

Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation.

scientific article published on 5 January 2006

Oncogenic Notch signaling in T-cell and B-cell lymphoproliferative disorders.

scientific article published on 28 April 2016

One-two punch injury to tolerance mechanisms in graft-versus-host disease

scientific article published on 01 April 2020

PI16+ reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial niches

scientific article published in 2023

Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice

scientific article published on 14 June 2016

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo

scientific article published on 26 March 2015

Regulation of lymphoid development, differentiation, and function by the Notch pathway.

scientific article

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.

scientific article

Role of the immune response induced by superantigens in the pathogenesis of microbial infections.

scientific article published on January 1997

STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease

scientific article published on 23 December 2013

Selective thymus settling regulated by cytokine and chemokine receptors

scientific article published on 01 February 2007

Small-molecule BCL6 inhibitor effectively treats mice with non-sclerodermatous chronic graft-versus-host disease

article

Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development

scientific article published on 03 August 2018

Subcutaneous panniculitis-like T-cell lymphoma with bone marrow involvement.

scientific article

T Cell-Restricted Notch Signaling Contributes to Pulmonary Th1 and Th2 Immunity during Cryptococcus neoformans Infection.

scientific article published on 14 June 2017

T Cell–Specific Notch Inhibition Blocks Graft-versus-Host Disease by Inducing a Hyporesponsive Program in Alloreactive CD4+ and CD8+ T Cells ⬇️

scientific article published on June 1, 2013

T-ing up inflammation in fat

scientific article published on 01 August 2009

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.

scientific article published on 16 March 2016

Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

scientific article published on 19 March 2019

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

scientific article published on 7 April 2015

Targeting the Notch Pathway to Prevent Rejection.

scientific article published on April 2016

The FOSSIL Study: FLAG or standard 7+3 induction therapy in secondary acute myeloid leukemia

scientific article published on 01 June 2018

The Histone Methyltransferase Gene Absent, Small, or Homeotic Discs-1 Like Is Required for Normal Hox Gene Expression and Fertility in Mice

scientific journal article

The PAF1c Subunit CDC73 Is Required for Mouse Hematopoietic Stem Cell Maintenance but Displays Leukemia-Specific Gene Regulation

article

The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia

scientific journal article

The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.

scientific article

The shelterin complex and hematopoiesis.

scientific article published on 2 May 2016

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

scientific article published on 6 July 2016

Transient blockade of delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation.

scientific article

Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia

scientific article

Trithorax group genes in hematopoiesis.

scientific article published in July 2015

Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase.

scientific article published on 20 August 2015

Use of botulinum toxin type A to avoid tracheal intubation or tracheostomy in severe paradoxical vocal cord movement

scientific article published on 01 September 2000

Use of ibritumomab tiuxetan anti-CD20 radioimmunotherapy in a non-Hodgkin's lymphoma patient previously treated with a yttrium-90-labeled anti-CD22 monoclonal antibody.

scientific article published in June 2003

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