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List of works by Giuseppina Di Stefano

A ketogenic diet increases succinic dehydrogenase (SDH) activity and recovers age-related decrease in numeric density of SDH-positive mitochondria in cerebellar Purkinje cells of late-adult rats

scientific article

A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes

scientific article published in August 2009

Age-related effects of moderate alcohol consumption on GAP-43 levels in rat hippocampus.

scientific article

Alterations of synaptic turnover rate in aging may trigger senile plaque formation and neurodegeneration

scientific article published in January 2007

Baseline apoptosis of tumor cells as a response predictor to chemotherapy

scientific article published on 01 June 1997

Brain aging: The zinc connection.

scientific article

Cellular distribution of GAP-43 mRNA in hippocampus and cerebellum of adult rat brain by in situ RT-PCR

scientific article published on 01 September 2001

Comment on “Expression of amyloid beta peptide in human platelets: Pivotal role of the phospholipase Cγ2-protein kinase C pathway in platelet activation” by Shen et al

scientific article published on 10 July 2008

Contribution of non-reference alleles in mtDNA of Alzheimer's disease patients

scientific article

Cytochemical Estimation of Cytochrome Oxidase Activity as a Morphofunctional Mitochondrial Check-Up

scientific article published on 01 January 2006

Cytochrome oxidase activity in hippocampal synaptic mitochondria during aging: a quantitative cytochemical investigation.

scientific article published in June 2004

Decay of mitochondrial metabolic competence in the aging cerebellum

scientific article published in June 2004

Decreased Presence of Perforated Synapses in a Triple-Transgenic Mouse Model of Alzheimer's Disease

scientific article published on 01 April 2008

Dietary restriction modulates synaptic structural dynamics in the aging hippocampus

scientific article published on 01 July 1999

Differences in gene expression in the hippocampus of aged rats are associated with better long-term memory performance in a passive avoidance test

scientific article published in April 2010

Distribution of map2 in hippocampus and cerebellum of young and old rats by quantitative immunohistochemistry.

scientific article

Dose-dependent opposite effect of zinc on apoptosis in mouse thymocytes

scientific article published on 01 September 1995

Dynamin binding protein gene expression and memory performance in aged rats

scientific article published on 12 January 2011

Effect of melatonin and pineal grafting on thymocyte apoptosis in aging mice.

scientific article published in September 1996

Effect of two medium chain triglycerides-supplemented diets on synaptic morphology in the cerebellar cortex of late-adult rats

scientific article published in December 2009

Effect of zinc or zinc plus arginine supplementation on antibody titre and lymphocyte subsets after influenza vaccination in elderly subjects: a randomized controlled trial

scientific article published on 01 November 1998

Effects of ethanol on GAP-43 levels in hippocampus and cerebellum of aged rats.

scientific article

Evaluation of NK and LAK cell activities in neoplastic patients during treatment with morphine

scientific article published on 01 July 1991

GAP-43 mRNA detection by in situ hybridization, direct and indirect in situ RT-PCR in hippocampal and cerebellar tissue sections of adult rat brain

scientific article published in January 2003

Generation of human lymphokine-activated killer cells following an IL-2 pulse in elderly cancer patients

scientific article published on 01 February 1998

Immune enhancement by conditioning of senescent mice. Comparison of old and young mice in learning ability and in ability to increase natural killer cell activity and other host defense reactions in response to a conditioned stimulus.

scientific article published in November 1994

Impact of potentially inappropriate medications and polypharmacy on 3-month readmission among older patients discharged from acute care hospital: a prospective study

scientific article published on 11 November 2017

Impaired antibody response to influenza vaccine in institutionalized elderly

scientific article published on 01 June 1994

In vivo amifostine (WR-2721) prevents chemotherapy-induced apoptosis of peripheral blood lymphocytes from cancer patients

scientific article published on 01 January 1999

Ketogenic diets cause opposing changes in synaptic morphology in CA1 hippocampus and dentate gyrus of late-adult rats

scientific article published in June 2008

Ketogenic diets: an historical antiepileptic therapy with promising potentialities for the aging brain

scientific article published on 24 February 2010

Level and distribution of microtubule-associated protein-2 (MAP2) as an index of dendritic structural dynamics

scientific article

Long-term melatonin supplementation does not recover the impairment of natural killer cell activity and lymphocyte proliferation in aging mice

scientific article published on 01 January 1997

Mapping of mitochondrial metabolic competence by cytochrome oxidase and succinic dehydrogenase cytochemistry.

scientific article published in September 2001

Metallothionein isoforms (I+II and III) and interleukin-6 in the hippocampus of old rats: may their concomitant increments lead to neurodegeneration?

scientific article

Morphometric investigations of the mitochondrial damage in ceroid lipopigment accumulation due to vitamin E deficiency

scientific article published on 01 May 2002

Morphometry of age pigment (lipofuscin) and of ceroid pigment deposits associated with vitamin E deficiency

scientific article published in May 2002

Natural killer activity in stage III and IV endometriosis: impaired cytotoxicity and retained lymphokine responsiveness of natural killer cells

scientific article published on 01 June 1995

Neurobiology of the Aging Brain

Neuronal Death versus Synaptic Pathology in Alzheimer's Disease

scientific article published on 01 December 2003

Neuronal apoptosis in Alzheimer's disease: the role of age-related mitochondrial metabolic competence

scientific article published in August 2009

One-month strawberry-rich anthocyanin supplementation ameliorates cardiovascular risk, oxidative stress markers and platelet activation in humans

scientific article published on 27 November 2013

Optimization of cytotoxic assay by target cell retention of the fluorescent dye carboxyfluorescein diacetate (CFDA) and comparison with conventional 51CR release assay

scientific article published on 01 October 1992

Peripheral inflammatory biomarkers of Alzheimer's disease: the role of platelets

scientific article published on 09 May 2010

Platelet as a physiological model to investigate apoptotic mechanisms in Alzheimer beta-amyloid peptide production

scientific article published on 23 November 2007

Preservation of mitochondrial volume homeostasis at the early stages of age-related synaptic deterioration

scientific article published in January 2007

Prolactin increases the susceptibility of primary leukemia cells to NK and LAK effectors

scientific article published on 01 January 1996

Quantitative immunohistochemistry of glucose transport protein (Glut3) expression in the rat hippocampus during aging.

scientific article published in May 2001

Regulation of NK cell lymphokine responsiveness by pituitary-thyroid hormones during ontogeny in mice. Suggestion for a sequential neuroendocrine-immune cross-talk

scientific article published on 01 November 1994

Relationship between 17-beta-estradiol and prolactin in the regulation of natural killer cell activity during progression of endometriosis

scientific article published on 01 September 1995

Release of beta-amyloid from high-density platelets: implications for Alzheimer's disease pathology

scientific article published in January 2007

Role of diffuse low-level heteroplasmy of mitochondrial DNA in Alzheimer's disease neurodegeneration

scientific article published on 23 July 2015

Role of prolactin in the modulation of NK and LAK cell activity after short- or long-term morphine administration in neoplastic patients

scientific article published on 01 October 1996

Role of the low zinc bioavailability on cellular immune effectiveness in cystic fibrosis

scientific article published on 01 June 1995

Selective decline of the metabolic competence of oversized synaptic mitochondria in the old monkey cerebellum

scientific article published in April 2008

Selenium Concentrations and Mortality among Community-Dwelling Older Adults: Results from IlSIRENTE Study

scientific article published on 01 January 2018

Special considerations for the treatment of chronic kidney disease in the elderly.

scientific article published on 17 February 2016

Structural synaptic remodeling in the perirhinal cortex of adult and old rats following object-recognition visual training.

scientific article

Synaptic and mitochondrial morphometry provides structural correlates of successful brain aging

scientific article published on February 2007

Synaptic and mitochondrial physiopathologic changes in the aging nervous system and the role of zinc ion homeostasis

scientific article

Synaptic pathology in the brain cortex of old monkeys as an early alteration in senile plaque formation

scientific article

Synaptic remodeling in hippocampal CA1 region of aged rats correlates with better memory performance in passive avoidance test

scientific article published in April 2008

Testing mitochondrial metabolic competence by cytochrome oxidase preferential cytochemistry versus immunoreactivity of subunits I and IV.

scientific article published in January 2006

Vitamin E deficiency and aging effect on expression levels of GAP-43 and MAP-2 in selected areas of the brain

scientific article published in June 2004