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List of works by Emiliano Pena-Altamira

Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation.

scientific article

Copper-zinc superoxide dismutase (SOD1) is released by microglial cells and confers neuroprotection against 6-OHDA neurotoxicity

scientific journal article

Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo

scientific article published on 11 September 2019

Dietary Protein Source Influences Brain Inflammation and Memory in a Male Senescence-Accelerated Mouse Model of Dementia

scientific article published on 09 November 2020

Disease-related regressive alterations of forebrain cholinergic system in SOD1 mutant transgenic mice.

scientific article published on April 2005

Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells.

scientific article

Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells.

scientific article published on 2 March 2017

Histone post-translational modifications in Huntington's and Parkinson's diseases.

scientific article published on January 2013

Long-term dietary administration of valproic acid does not affect, while retinoic acid decreases, the lifespan of G93A mice, a model for amyotrophic lateral sclerosis

scientific article

Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose

scientific article published on 10 October 2018

Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects

scientific article

Neurochemical correlates of differential neuroprotection by long-term dietary creatine supplementation.

scientific article published on 6 September 2005

Neuronal Regulation of Neuroprotective Microglial Apolipoprotein E Secretion in Rat In Vitro Models of Brain Pathophysiology.

scientific article published in August 2015

New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents

scientific article published on 27 June 2017

Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.

scientific article

Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors.

scientific article

Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss

scientific article published on 28 October 2019

Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.

scientific article published on 26 December 2016

The transcription factor CCAAT enhancer-binding protein β protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms

scientific article published on 6 November 2013

Transcriptional profiling in the lumbar spinal cord of a mouse model of amyotrophic lateral sclerosis: a role for wild-type superoxide dismutase 1 in sporadic disease?

scientific article

Zinc supplementation in rats impairs hippocampal-dependent memory consolidation and dampens post-traumatic recollection of stressful event

scientific article