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List of works by Housheng Hansen He

8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.

scientific article

Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein.

scientific article published on October 2016

Androgen receptor and MYC equilibration centralizes on developmental super-enhancer

scientific article published on 15 December 2021

Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.

scientific article published on October 2011

BINOCh: binding inference from nucleosome occupancy changes.

scientific article

CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer

scientific article published on 19 March 2021

Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer

scientific article published on 31 August 2020

Crucial role of noncoding RNA in driving prostate cancer development and progression

scientific article published on 25 November 2016

Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics

scientific article

Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2

scientific article

Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response

scientific article

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

scientific article published on 15 February 2013

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent

scientific article

Early-life programming of mesenteric lymph node stromal cell identity by the lymphotoxin pathway regulates adult mucosal immunity

scientific article published on 01 December 2019

Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer

scientific article published on 11 December 2019

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

scientific article published on 13 June 2017

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Genomic hallmarks of localized, non-indolent prostate cancer.

scientific article published on 9 January 2017

GlcNAcylation of histone H2B facilitates its monoubiquitination

scientific article

Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes

scientific article published on 16 September 2020

High-dimensional genomic data bias correction and data integration using MANCIE

scientific article

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression.

scientific article published on 13 January 2017

LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression.

scientific article

Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity.

scientific article

MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A.

scientific article published on 17 June 2013

Modeling cis-regulation with a compendium of genome-wide histone H3K27ac profiles.

scientific article published on 27 July 2016

Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer.

scientific article published on 15 August 2016

N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

scientific article published on 10 October 2019

Noncoding RNA for personalized prostate cancer treatment: utilizing the 'dark matters' of the genome.

scientific article published on 25 January 2017

Nucleosome dynamics define transcriptional enhancers

scientific article

ONECUT2 is a driver of neuroendocrine prostate cancer

scientific article published in Nature Communications

PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy

scientific article published on 25 March 2015

Pioneer of prostate cancer: past, present and the future of FOXA1

scientific article published on 18 September 2020

Reactivation of androgen receptor-regulated lipid biosynthesis drives the progression of castration-resistant prostate cancer.

scientific article published on 23 October 2017

Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification

scientific article

Refined RIP-seq protocol for epitranscriptome analysis with low input materials

scientific article published on 13 September 2018

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

scientific article published on 6 January 2016

Systematic evaluation of factors influencing ChIP-seq fidelity

scientific article

TMPRSS2-ERG activates NO-cGMP signaling in prostate cancer cells

scientific article published on 04 February 2019

The DNA methylation landscape of advanced prostate cancer

scientific article published on 13 July 2020

Transcriptional landscape of the human cell cycle.

scientific article published on 13 March 2017

Variant Set Enrichment: an R package to identify disease-associated functional genomic regions.

scientific article published on 22 February 2017

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