List of works by Thomas Henry

A genome-wide screen identifies IRF2 as a key regulator of caspase-4 in human cells

scientific article published on 29 July 2019

A proximity-dependent biotinylation (BioID) approach flags the p62/sequestosome-1 protein as a caspase-1 substrate

scientific article published on 21 June 2018

AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity

scientific article

AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages.

scientific article published on 4 May 2012

ASC controls IFN-γ levels in an IL-18-dependent manner in caspase-1-deficient mice infected with Francisella novicida

scientific article published on 23 August 2013

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.

scientific article

Activation of the inflammasome upon Francisella tularensis infection: interplay of innate immune pathways and virulence factors.

scientific article published on 27 July 2007

Asparagine assimilation is critical for intracellular replication and dissemination of Francisella

scientific article published on 8 November 2013

Caspase-11 controls interleukin-1β release through degradation of TRPC1.

scientific article

Catch me if you can

scientific article

Characterization of the Inflammasome in Human Kupffer Cells in Response to Synthetic Agonists and Pathogens.

scientific article

Contribution of flagellin pattern recognition to intestinal inflammation during Salmonella enterica serotype typhimurium infection

scientific article published on 23 February 2009

Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System

scientific article published on 02 October 2019

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

scientific article published on 24 August 2008

Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner.

scientific article

Deletion of Inflammasome Components Is Not Sufficient To Prevent Fatal Inflammation in Models of Familial Hemophagocytic Lymphohistiocytosis.

scientific article

Differential Interaction of the Staphylococcal Toxins Panton-Valentine Leukocidin and γ-Hemolysin CB with Human C5a Receptors

scientific article published on 19 June 2015

Francisella IglG protein and the DUF4280 proteins: PAAR-like proteins in non-canonical Type VI secretion systems?

scientific article published on 29 October 2016

Francisella Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium.

scientific article

Fulminant Staphylococcal Infections

scientific article published on 01 October 2018

Geoepidemiology and Immunologic Features of Autoinflammatory Diseases: a Comprehensive Review.

scientific article published on 03 June 2017

Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape

scientific article published on 16 January 2014

Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms

scientific article published on 15 June 2020

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida

scientific article published on 16 March 2015

Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin.

scientific article

Human Monocyte-Derived Osteoclasts Are Targeted by Staphylococcal Pore-Forming Toxins and Superantigens

scientific article

Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11.

scientific article published on 16 January 2018

Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β

scientific article published on 08 August 2018

IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection.

scientific article published on 2 October 2017

Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts

scientific article

Improved methods for producing outer membrane vesicles in Gram-negative bacteria.

scientific article published in July 2004

In vivo negative selection screen identifies genes required for Francisella virulence

scholarly article

Inflammasome activation restricts Legionella pneumophila replication in primary microglial cells through flagellin detection.

scientific article published on 28 January 2013

Inflammasomes in human diseases

scientific article

Inherited anomalies of innate immune receptors in pediatric-onset inflammatory diseases

scientific article published on 09 August 2015

Interleukin-1, inflammasome and autoinflammatory diseases

scientific article

Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signalling

scientific article published on 25 February 2019

Irgm2 and Gate-16 cooperatively dampen Gram-negative bacteria-induced caspase-11 response

scientific article published on 30 October 2020

Kineret®/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection

scientific article

LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.

scientific article published on 19 February 2018

Molecular motors hijacking by intracellular pathogens.

scientific article

NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly

scientific article published on 06 October 2021

Necrotizing Soft Tissue Infection Staphylococcus aureus but not S. pyogenes Isolates Display High Rates of Internalization and Cytotoxicity Toward Human Myoblasts

scientific article published in 2019

Pathogenesis of adult-onset Still's disease: new insights from the juvenile counterpart.

scientific article

Pre-existing antibody-mediated adverse effects prevent the clinical development of a bacterial anti-inflammatory protein

scientific article published on 29 May 2020

Publisher Correction: Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin

scientific article published on 01 October 2018

Pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patients

scientific article published on 07 October 2019

Regulation of mouse NK cell development and function by cytokines

scientific article published on 12 December 2013

S1PR5 is pivotal for the homeostasis of patrolling monocytes.

scientific article published on 30 April 2013

Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes

scientific article

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow

scientific article published on 10 February 2014

The inflammasomes: platforms of innate immunity

scientific article

The pyrin inflammasome: from sensing RhoA GTPases-inhibiting toxins to triggering autoinflammatory syndromes

scientific article published on 01 April 2018

The staphylococcal toxin Panton-Valentine Leukocidin targets human C5a receptors.

scientific article published on May 2013

The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors

scientific article

The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche.

scientific article published on 2 October 2006

The virulence protein SopD2 regulates membrane dynamics of Salmonella-containing vacuoles

scientific article published on 15 July 2010

Transcriptional Regulation of Inflammasomes

scientific article published on 29 October 2020

Treatment of adult-onset Still's disease: a review

scientific article

Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections

scientific article

[Guanylate binding proteins: new proteins from the cell host cytosol involved in antibacterial immunity]

scientific article published on 01 June 2015