List of works - Trevor Humby

A novel translational assay of response inhibition and impulsivity: effects of prefrontal cortex lesions, drugs used in ADHD, and serotonin 2C receptor antagonism.

scientific article published on 9 May 2013

A pharmacological mouse model suggests a novel risk pathway for postpartum psychosis.

scientific article published on 28 September 2016

Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease.

scientific article published in November 2006

Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice.

scientific article

An mTph2 SNP gives rise to alterations in extracellular 5-HT levels, but not in performance on a delayed-reinforcement task

scientific article

Assaying dissociable elements of behavioural inhibition and impulsivity: translational utility of animal models

scientific article

Behavioral effects of psychomotor stimulants in rats with dorsal or ventral subiculum lesions: locomotion, cocaine self-administration, and prepulse inhibition of startle

scientific article

Behavioural and Psychiatric Phenotypes in Men and Boys with X-Linked Ichthyosis: Evidence from a Worldwide Online Survey

scientific article

Behavioural and cognitive abnormalities in an imprinting centre deletion mouse model for Prader-Willi syndrome

scientific article

Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome

scientific article published on 03 June 2015

Circadian and photoperiodic time measurement in male Syrian hamsters following lesions of the melatonin-binding sites of the paraventricular thalamus

scientific article published in January 1992

Common genetic effects on variation in impulsivity and activity in mice.

scientific article published in July 2004

Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention.

scientific article published on 28 February 2009

Differential effects of forebrain 5-hydroxytryptamine depletions on Pavlovian aversive conditioning to discrete and contextual stimuli in the rat.

scientific article published in October 1995

Dissociable effects of Sry and sex chromosome complement on activity, feeding and anxiety-related behaviours in mice

scientific article

Dopaminergic and behavioral changes in a loss-of-imprinting model of Cdkn1c

scientific article published on 31 August 2017

Effects of 5-HT2C, 5-HT1A receptor challenges and modafinil on the initiation and persistence of gambling behaviours

scientific article published on 02 March 2020

Effects of regional striatal lesions on motor, motivational, and executive aspects of progressive-ratio performance in rats.

scientific article

Enhanced appetitive learning and reversal learning in a mouse model for Prader-Willi syndrome

scientific article published in June 2012

Enhancement of amphetamine-induced locomotor activity and dopamine release in nucleus accumbens following excitotoxic lesions of the hippocampus.

scientific article

Genetic and pharmacological modulation of the steroid sulfatase axis improves response control; comparison with drugs used in ADHD.

scientific article

Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine.

scientific article published in April 1999

Impairments in impulse control in mice transgenic for the human FTDP-17 tauV337M mutation are exacerbated by age.

scientific article

Imprinted Nesp55 influences behavioral reactivity to novel environments

scientific article

Impulsive Choice in Mice Lacking Paternal Expression of Grb10 Suggests Intragenomic Conflict in Behavior.

scientific article published on 21 March 2018

Impulsive choice in mice lacking paternal expression ofGrb10suggests intra-genomic conflict in behavior

Impulsive choices in mice lacking imprinted Nesp55.

scientific article

Isolation rearing in rats: pre- and postsynaptic changes in striatal dopaminergic systems

scientific article published on April 1998

Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia.

scientific article

Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour

scientific article

Maternal deprivation of neonatal rats produces enduring changes in dopamine function.

scientific article published in April 1999

Measuring impulsivity in mice using a novel operant delayed reinforcement task: effects of behavioural manipulations and d-amphetamine

scientific article published on 30 August 2003

Measuring risk-taking in mice: balancing the risk between seeking reward and danger

scientific article published on 28 November 2013

Mice lacking paternal expression of imprinted Grb10 are risk-takers

scientific article published on 26 February 2020

Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism

scientific article published on August 2001

Mood symptoms, neurodevelopmental traits, and their contributory factors in X‐linked ichthyosis, ichthyosis vulgaris and psoriasis

scientific article published in 2022

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination

scientific article

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

scientific article

Placental programming of anxiety in adulthood revealed by Igf2-null models.

scientific article

Steroid sulfatase-deficient mice exhibit endophenotypes relevant to attention deficit hyperactivity disorder.

scientific article published on July 2011

The effects of automatic spelling correction software on understanding and comprehension in compensated dyslexia: improved recall following dictation.

scientific article published on 29 June 2014

The effects of isolation-rearing of rats on behavioural responses to food and environmental novelty

scientific article

The effects of isolation-rearing on preference by rats for a novel environment

scientific article

The effects of isolation-rearing on sucrose consumption in rats

scientific article

The role of N-methyl-d-aspartate-type glutamatergic neurotransmission in the photic induction of immediate-early gene expression in the suprachiasmatic nuclei of the Syrian hamster.

scientific article

Transgenic expression of the FTDP-17 tauV337M mutation in brain dissociates components of executive function in mice.

scientific article

Visuospatial attentional functioning in mice: interactions between cholinergic manipulations and genotype

scientific article published on 01 August 1999

What are imprinted genes doing in the brain?

scientific article published on January 2008

X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder

scientific article published on 8 December 2006

Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice

scientific article

List of works by Trevor Humby

A novel translational assay of response inhibition and impulsivity: effects of prefrontal cortex lesions, drugs used in ADHD, and serotonin 2C receptor antagonism.

A pharmacological mouse model suggests a novel risk pathway for postpartum psychosis.

Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease.

Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice.

An mTph2 SNP gives rise to alterations in extracellular 5-HT levels, but not in performance on a delayed-reinforcement task

Assaying dissociable elements of behavioural inhibition and impulsivity: translational utility of animal models

Behavioral effects of psychomotor stimulants in rats with dorsal or ventral subiculum lesions: locomotion, cocaine self-administration, and prepulse inhibition of startle

Behavioural and Psychiatric Phenotypes in Men and Boys with X-Linked Ichthyosis: Evidence from a Worldwide Online Survey

Behavioural and cognitive abnormalities in an imprinting centre deletion mouse model for Prader-Willi syndrome

Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome

Circadian and photoperiodic time measurement in male Syrian hamsters following lesions of the melatonin-binding sites of the paraventricular thalamus

Common genetic effects on variation in impulsivity and activity in mice.

Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention.

Differential effects of forebrain 5-hydroxytryptamine depletions on Pavlovian aversive conditioning to discrete and contextual stimuli in the rat.

Dissociable effects of Sry and sex chromosome complement on activity, feeding and anxiety-related behaviours in mice

Dopaminergic and behavioral changes in a loss-of-imprinting model of Cdkn1c

Effects of 5-HT2C, 5-HT1A receptor challenges and modafinil on the initiation and persistence of gambling behaviours

Effects of regional striatal lesions on motor, motivational, and executive aspects of progressive-ratio performance in rats.

Enhanced appetitive learning and reversal learning in a mouse model for Prader-Willi syndrome

Enhancement of amphetamine-induced locomotor activity and dopamine release in nucleus accumbens following excitotoxic lesions of the hippocampus.

Genetic and pharmacological modulation of the steroid sulfatase axis improves response control; comparison with drugs used in ADHD.

Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine.

Impairments in impulse control in mice transgenic for the human FTDP-17 tauV337M mutation are exacerbated by age.

Imprinted Nesp55 influences behavioral reactivity to novel environments

Impulsive Choice in Mice Lacking Paternal Expression of Grb10 Suggests Intragenomic Conflict in Behavior.

Impulsive choice in mice lacking paternal expression ofGrb10suggests intra-genomic conflict in behavior

Impulsive choices in mice lacking imprinted Nesp55.

Isolation rearing in rats: pre- and postsynaptic changes in striatal dopaminergic systems

Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia.

Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour

Maternal deprivation of neonatal rats produces enduring changes in dopamine function.

Measuring impulsivity in mice using a novel operant delayed reinforcement task: effects of behavioural manipulations and d-amphetamine

Measuring risk-taking in mice: balancing the risk between seeking reward and danger

Mice lacking paternal expression of imprinted Grb10 are risk-takers

Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism

Mood symptoms, neurodevelopmental traits, and their contributory factors in X‐linked ichthyosis, ichthyosis vulgaris and psoriasis

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

Placental programming of anxiety in adulthood revealed by Igf2-null models.

Steroid sulfatase-deficient mice exhibit endophenotypes relevant to attention deficit hyperactivity disorder.

The effects of automatic spelling correction software on understanding and comprehension in compensated dyslexia: improved recall following dictation.

The effects of isolation-rearing of rats on behavioural responses to food and environmental novelty

The effects of isolation-rearing on preference by rats for a novel environment

The effects of isolation-rearing on sucrose consumption in rats

The role of N-methyl-d-aspartate-type glutamatergic neurotransmission in the photic induction of immediate-early gene expression in the suprachiasmatic nuclei of the Syrian hamster.

Transgenic expression of the FTDP-17 tauV337M mutation in brain dissociates components of executive function in mice.

Visuospatial attentional functioning in mice: interactions between cholinergic manipulations and genotype

What are imprinted genes doing in the brain?

X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder

Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice