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List of works by Kazuhiro Aoki

A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss

scientific article

A novel underuse model shows that inactivity but not ovariectomy determines the deteriorated material properties and geometry of cortical bone in the tibia of adult rats.

scientific article

A peptide that blocks the interaction of NF-κB p65 subunit with Smad4 enhances BMP2-induced osteogenesis.

scientific article published on 16 April 2018

A structural modulator of tumor necrosis factor type 1 receptor promotes bone formation under lipopolysaccharide-induced inflammation in a murine tooth extraction model

scientific article published on 20 January 2012

A threshold of mechanical strain intensity for the direct activation of osteoblast function exists in a murine maxilla loading model

scientific article published on 17 November 2015

A tumor necrosis factor receptor loop peptide mimic inhibits bone destruction to the same extent as anti-tumor necrosis factor monoclonal antibody in murine collagen-induced arthritis

scientific article published in April 2007

A tumor necrosis factor-alpha antagonist inhibits inflammatory bone resorption induced by Porphyromonas gingivalis infection in mice

scientific article published in April 2006

Accumulation of p100, a precursor of NF-κB2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice.

scientific article

Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody

scientific article published on 23 June 2006

Amount of bone lengthening affects blood flow recovery and bone mineralization after distraction osteogenesis in a canine cleft palate model

scientific article

Bacterial Inhibition and Osteoblast Adhesion on Ti Alloy Surfaces Modified by Poly(PEGMA-r-Phosmer) Coating

scientific article published on 05 July 2018

Bone mineral density of the mandible in ovariectomized rats: analyses using dual energy X-ray absorptiometry and peripheral quantitative computed tomography.

scientific article

Bovine deciduous dentine is more susceptible to osteoclastic resorption than permanent dentine: results of quantitative analyses.

scientific article

Bovine dentine organic matrix down-regulates osteoclast activity.

scientific article published on 20 March 2009

CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction.

scientific article

Decontamination of Anodized Implant Surface With Different Modalities for Peri-Implantitis Treatment: Lasers and Mechanical Debridement With Citric Acid.

scientific article

Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice

scientific article

Defective nuclear factor-κB-inducing kinase in aly/aly mice prevents bone resorption induced by local injection of lipopolysaccharide.

scientific article published on 29 December 2010

Delivery of RANKL-Binding Peptide OP3-4 Promotes BMP-2-Induced Maxillary Bone Regeneration.

scientific article published on 22 March 2016

Disruption of NF-κB1 prevents bone loss caused by mechanical unloading.

scientific article published in June 2013

Effect of ascorbic acid deficiency on primary and reparative dentinogenesis in non-ascorbate-synthesizing ODS rats

scientific article published on 01 October 1997

Effect of doxycycline-treated hydroxyapatite surface on bone apposition: A histomophometric study in murine maxillae

scientific article

Effect of recombinant human fibroblast growth factor-2 on bone formation in rabbit mandibular distraction models using beta-tricalcium phosphate

scientific article published on 11 February 2010

Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1

scientific article published on 13 February 2014

Effects of neurectomy and tenotomy on the bone mineral density and strength of tibiae

scientific article published on 01 August 2001

Effects of surface roughness of titanium implants on bone remodeling activity of femur in rabbits.

scientific article published in December 1997

Gelatin hydrogel as a carrier of recombinant human fibroblast growth factor-2 during rat mandibular distraction

scientific article published on 31 March 2014

Increased bone mass in adult prostacyclin-deficient mice.

scientific article published on 11 November 2009

Inhibition of BMP2-induced bone formation by the p65 subunit of NF-κB via an interaction with Smad4.

scientific article published on 16 July 2014

Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1.

scientific article

Inhibition of the classical NF-kappaB pathway prevents osteoclast bone-resorbing activity.

scientific article published on 27 January 2009

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

scientific article published in Nature

LPS-induced inhibition of osteogenesis is TNF-alpha dependent in a murine tooth extraction model

scientific article published in October 2009

Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model.

scientific article published on 22 January 2016

Lipopolysaccharide-induced bone resorption is increased in TNF type 2 receptor-deficient mice in vivo

scientific article published on 30 August 2008

Low-level ultrahigh-frequency and ultrashort-pulse blue laser irradiation enhances osteoblast extracellular calcification by upregulating proliferation and differentiation via transient receptor potential vanilloid 1.

scientific article published on 7 December 2017

Microgravity promotes osteoclast activity in medaka fish reared at the international space station

scientific article

NF-κB RELA-deficient bone marrow macrophages fail to support bone formation and to maintain the hematopoietic niche after lethal irradiation and stem cell transplantation

scientific article published on 07 June 2014

Nanogel-crosslinked nanoparticles increase the inhibitory effects of W9 synthetic peptide on bone loss in a murine bone resorption model.

scientific article

Occlusal disharmony-induced stress causes osteopenia of the lumbar vertebrae and long bones in mice

scientific article published on 9 January 2018

Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis.

scientific article

Peptide-based delivery to bone.

scientific article published on 16 June 2012

Peptide-induced de novo bone formation after tooth extraction prevents alveolar bone loss in a murine tooth extraction model

scientific article

Phytic acid: an alternative root canal chelating agent

scientific article published on 20 November 2014

Polysaccharide nanogel delivery of a TNF-alpha and RANKL antagonist peptide allows systemic prevention of bone loss

scientific article

Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation

scientific article published on 01 May 2010

Regional distinctions in cortical bone mineral density measured by pQCT can predict alterations in material property at the tibial diaphysis of the Cynomolgus monkey.

scientific article published on 5 October 2005

Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.

scientific article published on 26 November 2006

Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo

scientific article

Selective inhibition of NF-κB suppresses bone invasion by oral squamous cell carcinoma in vivo.

scientific article published on 23 February 2012

Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis

scientific article

Stimulation of bone formation in cortical bone of mice treated with a receptor activator of nuclear factor-κB ligand (RANKL)-binding peptide that possesses osteoclastogenesis inhibitory activity

scientific article published on 14 January 2013

Suppression of NF-kappaB increases bone formation and ameliorates osteopenia in ovariectomized mice

scientific article published on 01 September 2010

TGF-β in dentin matrix extract induces osteoclastogenesis in vitro.

scientific article

The deficiency of immunoregulatory receptor PD-1 causes mild osteopetrosis

article

The induction of RANKL molecule clustering could stimulate early osteoblast differentiation

scientific article published on 26 December 2018

The influence of mechanical stimulation on osteoclast localization in the mouse maxilla: bone histomorphometry and finite element analysis ⬇️

scientific article published on May 15, 2012

The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: a bone histomorphometric study. ⬇️

scientific article published on 12 September 2015

The intra-articular injection of RANKL-binding peptides inhibits cartilage degeneration in a murine model of osteoarthritis.

scientific article

The tumor necrosis factor type 2 receptor plays a protective role in tumor necrosis factor-α-induced bone resorption lacunae on mouse calvariae

scientific article published in June 2011

The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: increased resorption and osteopenia in me(v)/me(v) mutant mice

scientific article published on 01 September 1999

Trabecular bone turnover, bone marrow cell development, and gene expression of bone matrix proteins after low calcium feeding in rats

scientific article published on 01 December 1999

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