List of works - Elena Dreassi

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

scientific article published on 8 October 2010

A Drug Discovery Approach to a Reveal Novel Antioxidant Natural Source: The Case of Chestnut Burr Biomass

scientific article published in 2024

A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-]Pyrimidine Dual Src/P-Glycoprotein Inhibitor

scientific article published on 19 June 2019

A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation

scientific article

A unique domain for a unique target: selective inhibitors of host cell DDX3X to fight emerging viruses

scientific article published on 30 July 2020

Analysis of guazatine mixture by LC and LC–MS and antimycotic activity determination of principal components

article

Antihypertensive, cardio- and neuro-protective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats

scientific article published on 29 May 2020

Application of near-infrared reflectance spectrometry in the study of atopy. Part 1. Investigation of skin spectra

scientific article published on 01 August 1997

Application of near-infrared reflectance spectrometry to the analytical control of pharmaceuticals: ranitidine hydrochloride tablet production

scientific article published on 01 February 1996

Assessing the Efficiency of Molecular Markers for the Species Identification of Gregarines Isolated from the Mealworm and Super Worm Midgut

AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma

scientific article published on 05 March 2020

Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses

scientific article

CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction

scientific article

Characterization and comparison of Metarhizium strains isolated from Rhynchophorus ferrugineus

scientific article published on 6 June 2014

Chemical evaluation of the Rhynchophorus ferrugineus larvae fed on different substrates as human food source

scientific article published in January 2017

Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma

scientific article

Cuticle-degrading proteases and toxins as virulence markers of Beauveria bassiana (Balsamo) Vuillemin

scientific article

DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins

scientific article published on 07 May 2020

Design and optimization of the variables in the adsorptive stripping voltammetric determination of rufloxacin in tablets, human plasma and urine

scientific article published on 01 April 1995

Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.

scientific article

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

scientific article

Determination of levamisole in animal tissues using liquid chromatography with ultraviolet detection.

scientific article published in December 2001

Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data

scientific article

Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family

scientific article published on 20 February 2016

Dietary fatty acids influence the growth and fatty acid composition of the yellow mealworm Tenebrio molitor (Coleoptera: Tenebrionidae).

scientific article published on 12 January 2017

Drug analysis by near-infra-red reflectance spectroscopy. Determination of the active ingredient and water content in antibiotic powders

scientific article published on 01 January 1989

Efficient use of agricultural waste to naturally fortify <i>Tenebrio molitor</i> mealworms and evaluation of their nutraceutical properties

scientific article published in 2023

Experimental design in the development of voltammetric method for the assay of omeprazole

article

Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor

scientific article published on 09 April 2020

Front Cover: Bithiazole Inhibitors of Phosphatidylinositol 4‐Kinase (PI4KIIIβ) as Broad‐Spectrum Antivirals Blocking the Replication of SARS‐CoV‐2, Zika Virus, and Human Rhinoviruses (ChemMedChem 23/2021)

scientific article

GC-EI-MS analysis of fatty acid composition in brain and serum of twitcher mouse.

scientific article published on 11 September 2014

High-performance liquid chromatographic assay of erythromycin from biological matrix using electrochemical or ultraviolet detection

scientific article published on 01 June 2000

Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells

scientific article

Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

scientific article published on 22 February 2016

In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains

scientific article published on 20 December 2019

In vitro studies of simulated percutaneous absorption: Influence of various enhancers in the release of clonazepam from 2-hydroxyethyl acetate patches

scientific article published on 01 January 1998

Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria.

scientific article

LC/ESI/MS method for the quantitative detection of guazatine residues in cereals

scientific article published on 25 July 2007

Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach †

scientific article published on 03 December 2019

Near infrared reflectance spectroscopy in the study of atopy. Part 3. Interactions between the skin and fomblins

scientific article published on 01 November 1998

Near-infrared Reflectance Spectrometry in the Studyof AtopyPart 2. Interactions Between the Skin and Polyethylene Glycol 400, Isopropyl Myristate and Hydrogel

scientific article published on 01 August 1997

New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors

scientific article

Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients.

scientific article published on 2 June 2015

Plasmin-Binding Tripeptide-Decorated Liposomes Loading Pyrazolo[3,4-d]pyrimidines for Targeting Hepatocellular Carcinoma

scientific article published on 07 May 2018

Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII.

scientific article published on 22 December 2017

Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.

scientific article

Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors

scientific article published on 20 May 2013

Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line.

scientific article

Quantification of psychosine in the serum of twitcher mouse by LC–ESI-tandem-MS analysis ⬇️

scientific article published on March 4, 2013

Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides.

scientific article

SRC family kinase inhibition through a new pyrazolo[3,4-d]pyrimidine derivative as a feasible approach for glioblastoma treatment

scientific article published on May 2015

Serum Metabolomics and Proteomics to Study the Antihypertensive Effect of Protein Extracts from Tenebrio molitor

scientific article published in 2022

Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors

scientific article published on 29 April 2015

Synthesis and biological evaluation of guanidino compounds endowed with subnanomolar affinity as competitive inhibitors of maize polyamine oxidase.

scientific article published in August 2009

Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity

scientific article published on 14 October 2014

Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors

article

Thin-layer chromatography and densitometry in drug assay: comparison of methods for monitoring valproic acid in plasma

scientific article published on 01 January 1990

List of works by Elena Dreassi

2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo[3,4-d]pyrimidines Src-Abl dual inhibitors.

A Drug Discovery Approach to a Reveal Novel Antioxidant Natural Source: The Case of Chestnut Burr Biomass

A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-]Pyrimidine Dual Src/P-Glycoprotein Inhibitor

A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation

A unique domain for a unique target: selective inhibitors of host cell DDX3X to fight emerging viruses

Analysis of guazatine mixture by LC and LC–MS and antimycotic activity determination of principal components

Antihypertensive, cardio- and neuro-protective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats

Application of near-infrared reflectance spectrometry in the study of atopy. Part 1. Investigation of skin spectra

Application of near-infrared reflectance spectrometry to the analytical control of pharmaceuticals: ranitidine hydrochloride tablet production

Assessing the Efficiency of Molecular Markers for the Species Identification of Gregarines Isolated from the Mealworm and Super Worm Midgut

AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma

Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses

CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction

Characterization and comparison of Metarhizium strains isolated from Rhynchophorus ferrugineus

Chemical evaluation of the Rhynchophorus ferrugineus larvae fed on different substrates as human food source

Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma

Cuticle-degrading proteases and toxins as virulence markers of Beauveria bassiana (Balsamo) Vuillemin

DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins

Design and optimization of the variables in the adsorptive stripping voltammetric determination of rufloxacin in tablets, human plasma and urine

Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

Determination of levamisole in animal tissues using liquid chromatography with ultraviolet detection.

Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data

Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family

Dietary fatty acids influence the growth and fatty acid composition of the yellow mealworm Tenebrio molitor (Coleoptera: Tenebrionidae).

Drug analysis by near-infra-red reflectance spectroscopy. Determination of the active ingredient and water content in antibiotic powders

Efficient use of agricultural waste to naturally fortify <i>Tenebrio molitor</i> mealworms and evaluation of their nutraceutical properties

Experimental design in the development of voltammetric method for the assay of omeprazole

Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor

Front Cover: Bithiazole Inhibitors of Phosphatidylinositol 4‐Kinase (PI4KIIIβ) as Broad‐Spectrum Antivirals Blocking the Replication of SARS‐CoV‐2, Zika Virus, and Human Rhinoviruses (ChemMedChem 23/2021)

GC-EI-MS analysis of fatty acid composition in brain and serum of twitcher mouse.

High-performance liquid chromatographic assay of erythromycin from biological matrix using electrochemical or ultraviolet detection

Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells

Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains

In vitro studies of simulated percutaneous absorption: Influence of various enhancers in the release of clonazepam from 2-hydroxyethyl acetate patches

Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria.

LC/ESI/MS method for the quantitative detection of guazatine residues in cereals

Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach †

Near infrared reflectance spectroscopy in the study of atopy. Part 3. Interactions between the skin and fomblins

Near-infrared Reflectance Spectrometry in the Studyof AtopyPart 2. Interactions Between the Skin and Polyethylene Glycol 400, Isopropyl Myristate and Hydrogel

New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors

Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients.

Plasmin-Binding Tripeptide-Decorated Liposomes Loading Pyrazolo[3,4-d]pyrimidines for Targeting Hepatocellular Carcinoma

Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII.

Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.

Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors

Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line.

Quantification of psychosine in the serum of twitcher mouse by LC–ESI-tandem-MS analysis ⬇️

Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides.

SRC family kinase inhibition through a new pyrazolo[3,4-d]pyrimidine derivative as a feasible approach for glioblastoma treatment

Serum Metabolomics and Proteomics to Study the Antihypertensive Effect of Protein Extracts from Tenebrio molitor

Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors

Synthesis and biological evaluation of guanidino compounds endowed with subnanomolar affinity as competitive inhibitors of maize polyamine oxidase.

Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity

Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors

Thin-layer chromatography and densitometry in drug assay: comparison of methods for monitoring valproic acid in plasma