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List of works by Jaclyn F Hechtman

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors

scientific article published on 3 June 2017

A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with ROS1-Rearranged Lung Cancer

scientific article published on 16 December 2015

AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants.

scientific article published on 24 February 2015

ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.

scientific article published in December 2017

ARID1A expression in early stage colorectal adenocarcinoma: an exploration of its prognostic significance.

scientific article published on 02 March 2016

Additional Primary Malignancies in Patients with Gastrointestinal Stromal Tumor (GIST): A Clinicopathologic Study of 260 Patients with Molecular Analysis and Review of the Literature

scientific article published on 7 January 2015

Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade

scientific article published on 01 April 2019

Anti-glutamate receptor 2 as a new potential diagnostic probe for prostatic adenocarcinoma: a pilot immunohistochemical study

scientific article

BRAF mutation predicts for poor outcomes after metastasectomy in patients with metastatic colorectal cancer.

scientific article published on 15 April 2014

Carcinoma ex microcystic adenoma of the pancreas: a report of a novel form of malignancy in serous neoplasms

scientific article published on 01 February 2012

Cellular localization of PD-L1 expression in mismatch-repair-deficient and proficient colorectal carcinomas.

scientific article

Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival

scientific article published on 9 February 2017

Clinical Features and Outcomes of Patients with Colorectal Cancers Harboring NRAS Mutations

scientific article published on 26 April 2017

Clinical and genetic determinants of ovarian metastases from colorectal cancer.

scientific article published on 22 November 2016

Clonal relatedness and mutational differences between upper tract and bladder urothelial carcinoma

scientific article published on 23 October 2018

Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions

scientific article published on 14 January 2019

Colorectal carcinoma with double somatic mismatch repair gene inactivation: clinical and pathological characteristics and response to immune checkpoint blockade

scientific article published on 07 June 2019

Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention

scientific article published on 30 May 2018

Corpora amylacea in gastrointestinal leiomyomas: a clinical, light microscopic, ultrastructural and immunohistochemical study with comparison to hyaline globules

scientific article published on 6 July 2013

Detection of NTRK Fusions: Merits and Limitations of Current Diagnostic Platforms

scientific article published on 13 June 2019

EBV-associated lymphoepithelioma-like carcinoma of the pancreas: Case report with targeted sequencing analysis.

scientific article published on 9 April 2015

EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer

scientific article published on 21 November 2018

ESMO recommendations on the standard methods to detect NTRK fusions in daily practice and clinical research

scientific article published on 01 September 2019

Efficacy of Combined VEGFR1-3, PDGFα/β, and FGFR1-3 Blockade Using Nintedanib for Esophagogastric Cancer

scientific article published on 05 April 2019

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.

scientific article published in February 2018

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

scientific article published on 01 August 2017

FOLFCIS Treatment and Genomic Correlates of Response in Advanced Anal Squamous Cell Cancer

scientific article published on 21 September 2018

Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer.

scientific article published on 9 November 2017

Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response

scientific article published on 01 May 2019

Germline SDHA mutations in children and adults with cancer

scientific article published on 01 August 2018

HER2/neu gene amplification and protein overexpression in gastric and gastroesophageal junction adenocarcinoma: a review of histopathology, diagnostic testing, and clinical implications.

scientific article published on June 2012

Hepatic mass in a 73-year-old man

scientific article published on 26 January 2012

Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF

scientific article published on 11 December 2015

Immunohistochemical null-phenotype for mismatch repair proteins in colonic carcinoma associated with concurrent MLH1 hypermethylation and MSH2 somatic mutations.

scientific article

Increased spinal c-Fos expression with noxious and non-noxious peripheral stimulation after severe spinal contusion

scientific article published on 11 December 2006

Intraductal polypoid lipid-rich neuroendocrine tumor of the pancreas with entrapped ductules: case report and review of the literature.

scientific article published on March 2013

Intramuscular corpora amylacea adjacent to ileal low-grade neuroendocrine tumours (typical carcinoids): a light microscopic, immunohistochemical and ultrastructural study

scientific article published on 26 February 2013

Ischemic bowel due to embolization from an isolated mobile thrombus of the ascending aorta: a case report and review of the literature.

scientific article published on August 2011

Loss of central inhibition: implications for behavioral hypersensitivity after contusive spinal cord injury in rats.

scientific article

MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation.

scientific article published on 08 March 2017

Majority of -Mutant and -Deficient Colorectal Carcinomas Achieve Clinical Benefit From Immune Checkpoint Inhibitor Therapy and Are Microsatellite Instability-High

scientific article published on 04 March 2019

Massive upper gastrointestinal hemorrhage due to adenosquamous carcinoma of the pancreas: Case report and literature review.

scientific article published on June 2011

Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition.

scientific article published on 26 September 2017

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

scientific article published on 20 March 2015

Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer

scientific article published on 30 October 2018

Multiple endocrine neoplasia type 1 associated with a new mutation in the menin gene and a midgut neuroendocrine tumor

article

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

scientific article published on 8 May 2017

Mycobacterial pseudotumor of the plantar fascia: how common is it? ⬇️

scientific article published on 04 April 2013

NTRK Fusions Define a Novel Uterine Sarcoma Subtype With Features of Fibrosarcoma.

scientific article published on 16 March 2018

Neurogenic polyps of the gastrointestinal tract: a clinicopathologic review with emphasis on differential diagnosis and syndromic associations

scientific article published on January 2015

Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing.

scientific article published on 27 November 2014

Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies

scientific article published on 06 August 2018

Outcomes following resection of intrahepatic cholangiocarcinoma

scientific article

Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma.

scientific article published on 22 July 2016

Performance of DAXX Immunohistochemistry as a Screen for DAXX Mutations in Pancreatic Neuroendocrine Tumors

scientific article published on 01 March 2019

Phase II study of trastuzumab with modified docetaxel, cisplatin, and 5 fluorouracil in metastatic HER2-positive gastric cancer

scientific article published on 07 August 2018

Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors: a pilot immunohistochemical study

scientific article published on 14 February 2013

Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next Generation Sequencing for Matching Patients to Targeted and Immune Therapies

scientific article published on 29 October 2018

RET fusions in a small subset of advanced colorectal cancers at risk of being neglected

scientific article published on 10 March 2018

Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer.

scientific article published on 3 May 2018

Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype

scientific article published on 28 July 2017

Rectal lymphogranuloma venereum mimicking cancer.

scientific article published on 05 September 2013

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma.

scientific article published on 29 May 2016

Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels

scientific article published on 28 March 2016

Sequencing of 279 cancer genes in ampullary carcinoma reveals trends relating to histologic subtypes and frequent amplification and overexpression of ERBB2 (HER2)

scientific article published on 15 May 2015

Somatic HNF1A mutations in the malignant transformation of hepatocellular adenomas: a retrospective analysis of data from MSK-IMPACT and TCGA

scientific article published on 17 August 2018

Subclinical focal Cholangitis mimicking liver metastasis in asymptomatic patients with history of pancreatic Ductal Adenocarcinoma and Biliary tree intervention

scientific article

Successful Targeted Therapy of Refractory Pediatric Fusion-Positive Secretory Breast Carcinoma

scientific article published on 18 August 2017

The past, present, and future of HER2 (ERBB2) in cancer: Approaches to molecular testing and an evolving role in targeted therapy

scientific article published on 02 April 2019

Thymomas diagnosed during pregnancy: two cases in young women without paraneoplastic or autoimmune disease.

scientific article published on 08 June 2011

Universal screening for microsatellite instability in colorectal cancer in the clinical genomics era: new recommendations, methods, and considerations

scientific article published on 01 October 2017

V211D Mutation in MEK1 Causes Resistance to MEK Inhibitors in Colon Cancer

scientific article published on 21 June 2019

Venous thromboembolism during pregnancy. Clinical suspicion warrants evaluation.

scientific article published on October 2003

Wegener's granulomatosis

scientific article published on 01 February 2009

What hides behind the MASC: clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC).

scientific article

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