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List of works by Toshio Matsumoto

2D7 diabody bound to the alpha2 domain of HLA class I efficiently induces caspase-independent cell death against malignant and activated lymphoid cells

scientific article

A Recombinant HLA Class I-Specific Single-Chain Fv Diabody Can Target Cancer Stem Cell-Like Side Population Cells in Multiple Myeloma.

scholarly article

A defucosylated anti-CD317 antibody exhibited enhanced antibody-dependent cellular cytotoxicity against primary myeloma cells in the presence of effectors from patients

scientific article published on 5 August 2010

A double-blinded head-to-head trial of minodronate and alendronate in women with postmenopausal osteoporosis

scientific article published on 2 March 2009

A new active vitamin D, ED-71, increases bone mass in osteoporotic patients under vitamin D supplementation: a randomized, double-blind, placebo-controlled clinical trial

scientific article published on 21 June 2005

A pilot study comparing the CGM-assessed glycemic profiles of patients with type 1 diabetes on insulin degludec and insulin glargine

scientific article published on 14 October 2016

A progressive auto-amplification loop in TAK1 expression and activation in myeloma cells

scholarly article

A single-chain Fv diabody against human leukocyte antigen-A molecules specifically induces myeloma cell death in the bone marrow environment

scientific article published on February 2007

A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome

scientific article published on 13 August 2004

Ability of myeloma cells to secrete macrophage inflammatory protein (MIP)-1alpha and MIP-1beta correlates with lytic bone lesions in patients with multiple myeloma

scientific article published in April 2004

Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib

scientific article published on 25 May 2013

Activation of peroxisome proliferator-activated receptor α in megakaryocytes reduces platelet-derived growth factor-BB in platelets.

scientific article published on 2 November 2010

Adrenomedullin enhances angiogenic potency of bone marrow transplantation in a rat model of hindlimb ischemia

scientific article

Aggressive antiplatelet therapy before coronary stent implantation in acute coronary syndrome with essential thrombocythemia--a case report

scientific article

An Acidic Milieu Created In Myeloma-Osteoclast Interaction Enhances Tumor Growth, but Triggers Anti-Myeloma Activity of Reveromycin A, a Novel Anti-Resorptive Agent

scholarly article

Androgen receptor counteracts Doxorubicin-induced cardiotoxicity in male mice

scientific article

Androgen receptor gene knockout male mice exhibit impaired cardiac growth and exacerbation of angiotensin II-induced cardiac fibrosis

scientific article published on 16 June 2005

Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling

scientific article published on 30 May 2013

Androgen-androgen receptor system protects against angiotensin II-induced vascular remodeling

scientific article published on 5 February 2009

Anti-neuronal antibodies in acute pandysautonomia

scientific article

Antitumor activity of humanized monoclonal antibody against HM1.24 antigen in human myeloma xenograft models

scientific article published on 01 February 2006

Apoptosis-related changes in skeletal muscles of patients with mitochondrial diseases

scientific article published on 31 October 2001

Aspirin inhibits thrombin action on endothelial cells via up-regulation of aminopeptidase N/CD13 expression

scientific article (publication date: November 2005)

Association of Th1 and Th2 cytokines with transient inflammatory reaction during lenalidomide plus dexamethasone therapy in multiple myeloma

scientific article published on 23 April 2013

Autologous peripheral blood-derived mononuclear cells induced by erythropoietin improve critical ischemic limbs

scientific article published on 15 February 2012

Beneficial effect of tacrolimus on myasthenia gravis with thymoma

scientific article published on 01 March 2007

Bisphosphonate Use May Reduce the Risk of Urolithiasis in Astronauts on Long‐Term Spaceflights

scientific article published in 2021

Bone-derived hormones and their systemic regulation

scientific article published in January 2018

Bone–fat linkage via interleukin-11 in response to mechanical loading

scholarly article

Bosentan ameliorated exercise-induced pulmonary arterial hypertension complicated with systemic sclerosis

scientific article published on November 2010

Bosentan improves systemic sclerosis-related peripheral circulation insufficiency

scientific article published on 05 February 2011

Carbohydrate-to-insulin ratio is estimated from 300-400 divided by total daily insulin dose in type 1 diabetes patients who use the insulin pump

scientific article published on 01 November 2012

Causes and differential diagnosis of hypocalcemia--recommendation proposed by expert panel supported by ministry of health, labour and welfare, Japan

scientific article published on 19 May 2008

Central motor conduction in cervical dystonia with cervical spondylotic myelopathy

scientific article

Chronic corticosteroid administration causes mitochondrial dysfunction in skeletal muscle

scientific article published in August 2002

Clinical usefulness of measurement of fibroblast growth factor 23 (FGF23) in hypophosphatemic patients: proposal of diagnostic criteria using FGF23 measurement

scientific article published on 05 March 2008

Clinical, pathological, and genetic features of limb-girdle muscular dystrophy type 2A with new calpain 3 gene mutations in seven patients from three Japanese families

scientific article published in November 1998

Combination Therapy of a Defucosylated Anti-HM1.24 Monoclonal Antibody Plus Lenalidomide Induces Marked Antibody-Dependent Cellular Cytotoxicity and Inhibits the Clonogenic Potential of Myeloma Cancer Stem-Like Cells

scholarly article

Combination Therapy of a Defucosylated Anti-HM1.24 Monoclonal Antibody Plus Lenalidomide Significantly Enhances Myeloma Cell Cytotoxicity Via Antibody-Dependent Cellular Cytotoxicity

scholarly article

Combination with a defucosylated anti-HM1.24 monoclonal antibody plus lenalidomide induces marked ADCC against myeloma cells and their progenitors

scientific article (publication date: 2013)

Comparison of angiogenic potency between mesenchymal stem cells and mononuclear cells in a rat model of hindlimb ischemia

scientific article published on 2 March 2005

Complicated paraneoplastic neurological syndromes: a report of two patients with small cell or non-small cell lung cancer

scientific article published in December 2003

Concise review: Defining and targeting myeloma stem cell-like cells

scientific article published on May 2014

Congenital ventricular aneurysm as an unexpected complication of monomorphic premature ventricular contractions

scientific article published on 14 May 2010

Construction of a conventional non-radioisotope method to quantify HM1.24 antigens: correlation of HM1.24 levels and ADCC activity of the humanized antibody against HM1.24.

scientific article published on 13 February 2006

Decrease in plasma brain natriuretic peptide level in the early phase after the start of carvedilol therapy is a novel predictor of long-term outcome in patients with chronic heart failure

scientific article published in October 2009

Decreased AP-1 activity and interleukin-11 expression by bone marrow stromal cells may be associated with impaired bone formation in aged mice

scientific article published on 01 August 2003

Dehydroepiandrosterone sulfate is inversely associated with sex-dependent diverse carotid atherosclerosis regardless of endothelial function

scientific article published on 2 June 2010

Delayed motor and sensory neuropathy in a patient with brainstem encephalitis

scientific article published in July 2005

Delayed treatment with vitamin C and N-acetyl-l-cysteine protects Schwann cells without compromising the anti-myeloma activity of bortezomib

scientific article published on April 28, 2011

Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors

scientific article published on 13 August 2003

Dermatomyositis with peripheral nervous system involvement: activation of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) in vasculitic lesions

scientific article published on 01 December 2003

Diabetic conditions differentially affect the endothelial function, arterial stiffness and carotid atherosclerosis

scientific article published on 8 January 2014

Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice

scientific article

Dissociation between titer of anti-ganglioside antibody and severity of symptoms in a case of Guillain–Barré syndrome with treatment-related fluctuation

scientific article published on June 15, 2003

Diurnal fluctuation of edema synchronized with plasma VEGF concentration in a patient with POEMS syndrome

scientific article published on 01 December 2002

Effect of aspirin treatment on serum concentrations of lipoprotein(a) in patients with atherosclerotic diseases

scientific article (publication date: September 2002)

Effect of eldecalcitol, an active vitamin D analog, on hip structure and biomechanical properties: 3D assessment by clinical CT

scientific article published on May 15, 2011

Effect of low-dose (1 mg/day) pitavastatin on left ventricular diastolic function and albuminuria in patients with hyperlipidemia

scientific article published on 31 March 2011

Effect of teriparatide on bone mineral density and biochemical markers in Japanese women with postmenopausal osteoporosis: a 6-month dose-response study

scientific article published on 01 November 2008

Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation

scientific article published on 10 September 2015

Effects of androgens on cardiovascular remodeling.

scientific article published on 05 April 2012

Effects of statins on cardiorenal syndrome.

scientific article

Effects of teriparatide on bone mineral density and bone turnover markers in Japanese subjects with osteoporosis at high risk of fracture in a 24-month clinical study: 12-month, randomized, placebo-controlled, double-blind and 12-month open-label ph

scientific article published on 24 May 2010

Efficacy of denosumab co-administered with vitamin D and Ca by baseline vitamin D status

scientific article published on 15 July 2020

Eldecalcitol is superior to alfacalcidol in maintaining bone mineral density in glucocorticoid-induced osteoporosis patients (e-GLORIA)

scientific article published on 05 March 2020

Emerging of Valproic Acid as an Anti-Myeloma Agent.

scholarly article

Endothelial Nitric Oxide Synthase-Independent Pleiotropic Effects of Pitavastatin Against Atherogenesis and Limb Ischemia in Mice

scientific article published on 6 June 2017

Endothelial nitric oxide synthase-independent protective action of statin against angiotensin II-induced atrial remodeling via reduced oxidant injury

scientific article published in March 2010

Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta

scientific article

Expanding phenotype and clinical heterogeneity in patients with identical mutation of the parkin gene

scientific article published in April 2004

Expression of RANK is dependent upon differentiation into the macrophage/osteoclast lineage: induction by 1alpha,25-dihydroxyvitamin D3 and TPA in a human myelomonocytic cell line, HL60.

scientific article

Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia.

scientific article published on 12 February 2010

Ezetimibe monotherapy ameliorates vascular function in patients with hypercholesterolemia through decreasing oxidative stress

scientific article published on 26 October 2011

Facilitation of Osteoblast Differentiation by ATF-4 Accumulation through Proteasome Inhibition.

scholarly article

Frontiers in vitamin D; basic research and clinical application. Eldecalcitol: the effect on bones and calcium metabolism

scientific article published on 01 November 2011

Glucocorticoid excess induces superoxide production in vascular endothelial cells and elicits vascular endothelial dysfunction

scientific article

Gold nanoparticle cluster-plasmon-enhanced fluorescent silica core-shell nanoparticles for X-ray computed tomography-fluorescence dual-mode imaging of tumors

scientific article published on 01 June 2013

Heparin cofactor II as a novel vascular protective factor against atherosclerosis.

scientific article published on 03 September 2009

Heparin cofactor II is a novel protective factor against carotid atherosclerosis in elderly individuals

scientific article

Heparin cofactor II is an independent protective factor against peripheral arterial disease in elderly subjects with cardiovascular risk factors

scientific article published on 30 April 2009

Heparin cofactor II protects against angiotensin II-induced cardiac remodeling via attenuation of oxidative stress in mice

scientific article published on 26 July 2010

Heparin cofactor II, a serine protease inhibitor, promotes angiogenesis via activation of the AMP-activated protein kinase-endothelial nitric-oxide synthase signaling pathway.

scientific article

High plasma aldosterone concentration is a novel risk factor of cognitive impairment in patients with hypertension

scientific article published on 23 September 2010

High plasma heparin cofactor II activity is associated with reduced incidence of in-stent restenosis after percutaneous coronary intervention

scientific article published on 26 January 2004

High serum parathyroid hormone and calcium are risk factors for hypertension in Japanese patients

scientific article published on 22 May 2014

Improvement of cardiac diastolic function and prognosis after autologous peripheral blood stem cell transplantation in AL cardiac amyloidosis

scientific article published on 15 October 2007

Increase in serum triglyceride was associated with coronary plaque vulnerability in a patient with rheumatoid arthritis

scientific article published on 06 June 2014

Induction of endosomal/lysosomal pathways in differentiating osteoblasts as revealed by combined proteomic and transcriptomic analyses

scientific article published on 02 August 2010

Infective endocarditis caused by lactobacillus

scientific article published on 16 June 2008

Inhibition of TACE Activity Enhances the Susceptibility of Myeloma Cells to TRAIL

scientific article published on February 28, 2012

Inhibition of thrombin action ameliorates insulin resistance in type 2 diabetic db/db mice.

scientific article published on 4 December 2009

Interferon-alpha enhances CD317 expression and the antitumor activity of anti-CD317 monoclonal antibody in renal cell carcinoma xenograft models

scientific article

Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice

scientific article published on 15 October 2002

Intra-vascular ultrasound findings of diffuse coronary atherosclerotic change in systemic lupus erythematosus with secondary antiphospholipid syndrome

scientific article published on 01 August 2006

Intravenous pamidronate prevents femoral bone loss and renal stone formation during 90-day bed rest.

scientific article published on 23 August 2004

Involvement of mitochondria in myasthenia gravis complicated with dermatomyositis and rheumatoid arthritis: a case report

scientific article published on 20 April 2005

Isolated cranial neuropathy associated with anti-glycolipid antibodies

scientific article published on 01 October 2004

Ligand-selective potentiation of rat mineralocorticoid receptor activation function 1 by a CBP-containing histone acetyltransferase complex

scientific article published on June 2002

Magnetically responsive smart nanoparticles for cancer treatment with a combination of magnetic hyperthermia and remote-control drug release

scientific article

Malignant B-lymphoid cells with bone lesions express receptor activator of nuclear factor-kappaB ligand and vascular endothelial growth factor to enhance osteoclastogenesis

scientific article published in September 2005

Marked improvement of platelet transfusion refractoriness after bortezomib therapy in multiple myeloma

scientific article published on 20 February 2009

Mechanical stress activates Smad pathway through PKCδ to enhance interleukin-11 gene transcription in osteoblasts

scientific article

Mechanical stress induces Interleukin-11 expression to stimulate osteoblast differentiation

scientific article published on 07 August 2009

Minodronate

scientific article published on 15 May 2020

Minodronate combined with alfacalcidol versus alfacalcidol alone for glucocorticoid-induced osteoporosis: a multicenter, randomized, comparative study

scientific article published on 22 January 2020

Mitochondrial damage in patients with long-term corticosteroid therapy: development of oculoskeletal symptoms similar to mitochondrial disease

scientific article published on 18 May 2002

Motor Neuron Involvement in a Patient with Long-term Corticosteroid Administration

scientific article published on September 1, 2003

Multi-Wavelength Analysis of 18$\mu $m-Selected Galaxies in the AKARI/Infrared-Camera monitor field towards the North Ecliptic Pole

Multiple myeloma complicated with disseminated zygomycosis after bortezomib therapy

scientific article published on August 2010

Myeloma cell-osteoclast interaction enhances angiogenesis together with bone resorption: a role for vascular endothelial cell growth factor and osteopontin

scientific article published in February 2007

Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2.

scientific article published on 19 July 2005

New approved drugs for osteoporosis in Japan

scientific article published on 01 June 2012

Non-invasive Measurement of Skin Autofluorescence as a Beneficial Surrogate Marker for Atherosclerosis in Patients with Type 2 Diabetes

scientific article published on 01 January 2015

Number and severity of prevalent vertebral fractures and the risk of subsequent vertebral fractures in Japanese women with osteoporosis: results from the minodronate trial

scientific article published on 26 March 2013

Optical Identification of 15$\mu $m Sources in the AKARI Performance Verification Field toward the North Ecliptic Pole

scientific article

Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion

scientific article published on 8 June 2004

Overexpressions of myoglobin and antioxidant enzymes in ragged‐red fibers of skeletal muscle from patients with mitochondrial encephalomyopathy

scientific article published on October 1, 2003

Oxidative stress-associated mitochondrial dysfunction in corticosteroid-treated muscle cells

scientific article published on July 2004

Parathyroid hormone (1-34) counteracts the suppression of interleukin-11 expression by glucocorticoid in murine osteoblasts: a possible mechanism for stimulating osteoblast differentiation against glucocorticoid excess

scientific article published on 8 February 2013

Parathyroid neoplasms: a state and view of clinical research

scientific article published on 01 March 2011

Parkin affects mitochondrial function and apoptosis in neuronal and myogenic cells

scientific article published on 4 August 2006

Parkin enhances mitochondrial biogenesis in proliferating cells

scientific article published on 31 January 2006

Persistent Activation of Calcium-Sensing Receptor Suppresses Bone Turnover, Increases Microcracks, and Decreases Bone Strength

scientific article published on 06 March 2019

Pim Inhibition Suppresses Osteoclastogenesis and Tumor Growth in Myeloma

scholarly article

Pim-2 is a critical target for treatment of osteoclastogenesis enhanced in myeloma

scientific article published on 17 October 2016

Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

scientific article

Pitavastatin, an HMG-CoA reductase inhibitor, exerts eNOS-independent protective actions against angiotensin II induced cardiovascular remodeling and renal insufficiency

scientific article published on 25 October 2007

Plasma heparin cofactor II activity is inversely associated with left atrial volume and diastolic dysfunction in humans with cardiovascular risk factors.

scientific article

Potent induction of activin A secretion from monocytes and bone marrow stromal fibroblasts by cognate interaction with activated T cells.

scientific article published in August 2002

Potentiation of bortezomib's Anti-Myeloma Effects in Combination with Anti-DR5 Agonistic Antibody: The Role of ER Stress in DR5 Editing and DR-Mediated Apoptotic Signaling

scholarly article

Predictive Factors for Efficacy of Dipeptidyl Peptidase-4 Inhibitors in Patients with Type 2 Diabetes Mellitus.

scientific article

RANKL as a target for the treatment of osteoporosis

scientific article published on 15 October 2020

Recent advances in the management of osteoporosis

scientific article

Reduced bone formation and increased adiposity with insulin resistance in interleukin-11 deficient mice

scholarly article

Relationship Between Bone Mineral Density and Risk of Vertebral Fractures with Denosumab Treatment in Japanese Postmenopausal Women and Men with Osteoporosis

scientific article published on 25 August 2020

Role for macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in the development of osteolytic lesions in multiple myeloma

scientific article published on 01 September 2002

SB431542, a TGF-Beta Receptor Kinase Inhibitor, Restores Bone Formation Which Ameliorates Myeloma-Induced Microenvironment.

scholarly article

Secondary osteoporosis UPDATE. Drugs under development for metabolic bone disease

scientific article published in May 2010

Serum carboxy-terminal telopeptide of type I collagen (ICTP) as a surrogate marker for vulnerable plaques in atherosclerotic patients: a pilot study

scientific article published on 6 April 2013

Size-controlled synthesis, surface functionalization, and biological applications of thiol-organosilica particles

scientific article published on 7 April 2010

Space flight/bedrest immobilization and bone. Bisphosphonate and the loss of bone mineral due to space flight or prolonged bed rest

scientific article published in December 2012

Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II-deficient mice

scientific article

Successful treatment with tacrolimus in a case of refractory dermatomyositis

scientific article published in November 2005

Superparamagnetic nanoparticle clusters for cancer theranostics combining magnetic resonance imaging and hyperthermia treatment

scientific article published on 23 April 2013

TAK1 is a pivotal therapeutic target for tumor progression and bone destruction in myeloma

scientific article published on 09 April 2020

Targeting myeloma–osteoclast interaction with Vγ9Vδ2 T cells

scientific article published on June 23, 2011

Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth

scientific article

The Role of Heparin Cofactor Ⅱ in the Regulation of Insulin Sensitivity and Maintenance of Glucose Homeostasis in Humans and Mice

scientific article published on 15 May 2017

The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome

scientific article (publication date: 27 June 2003)

Therapy with bortezomib plus dexamethasone induces osteoblast activation in responsive patients with multiple myeloma

scientific article

Transcriptional induction of FosB/DeltaFosB gene by mechanical stress in osteoblasts

scientific article

Transforming Growth Factor-β1 as a Common Target Molecule for Development of Cardiovascular Diseases, Renal Insufficiency and Metabolic Syndrome.

scientific article published on 28 December 2010

Transient inflammatory reaction during lenalidomide plus reduced-dose dexamethasone therapy in two patients with relapsed multiple myeloma

scientific article published on 01 February 2011

Up-regulation of hexokinaseII in myeloma cells: targeting myeloma cells with 3-bromopyruvate

scientific article published on February 1, 2012

Update and perspectives of anabolic therapies for osteoporosis

scientific article published on 01 March 2012

Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma

scientific article

Vascular smooth muscle cell proliferation is dependent upon upregulation of mitochondrial transcription factor A (mtTFA) expression in injured rat carotid artery.

scientific article

Vicious cycle between myeloma cell binding to bone marrow stromal cells via VLA-4-VCAM-1 adhesion and macrophage inflammatory protein-1alpha and MIP-1beta production

scientific article

Vitamin D and its derivatives as anti-osteoporotic drugs

scientific article published in April 2005

Vitamin D insufficiency defined by serum 25-hydroxyvitamin D and parathyroid hormone before and after oral vitamin D₃ load in Japanese subjects

scientific article published on 22 June 2010

[Biochemical markers in bone metastasis]

scientific article published on 01 July 2004

[Bisphosphonate and mechanical stress on bone]

scientific article published on 01 September 2008

[Bone architecture and strength on unloading]

scientific article published on 01 July 2013

[Bone remodeling: a role in bone homeostasis]

scientific article published on 01 May 2009

[Cancer Treatment-Induced Bone Loss(CTIBL)]

scientific article published on 01 December 2018

[Discovery and significance of parathyroid hormone]

scientific article published on 01 October 2005

[Effect of bisphosphonate on myeloma bone disease]

scientific article published on 01 May 2002

[Eldecalcitol (ED-71)]

scientific article published on 01 January 2011

[Glucocorticoid-induced reduction in NO bioavailability and vascular endothelial dysfunction]

scientific article published on 01 June 2007

[Hormones and osteoporosis update. Vitamin D and bone].

scientific article published in July 2009

[Mechanisms for formation of myeloma bone disease]

scientific article published on 01 April 2008

[Osteoporosis in RA: pathophysiology and treatment]

scientific article published on 01 January 2005

[Pathophysiology and classitication of parathyroidism]

scientific article published on 01 August 2007

[Phosphatonin]

scientific article published on 01 October 2007

[Physiopathology of and therapy for osteoporosis]

scientific article published on 01 October 2008

[Space flight/bedrest immobilization and bone. Bone metabolism in space flight and long-duration bed rest]

scientific article published on 01 December 2012

[Successful treatment of relapsed/refractory Hodgkin's lymphoma with tandem transplantation]

scientific article published on 01 October 2004

[The pathology, diagnosis and therapy on osteoporosis]

scientific article published on 01 October 2014

[Treatment of osteoporosis in daily medical practice: discussion]

scientific article published on 01 April 2005

[Useful clinical tests for early diagnosis of endocrine and metabolic disorders]

scientific article published on 01 December 2005

[Vitamin D-vitamin D receptor system regulates antithrombogenicity in vivo]

scientific article published on 01 July 2006

c-Fos degradation by the ubiquitin-proteasome proteolytic pathway in osteoclast progenitors

scientific article published on 19 September 2005