List of works - Hisatsugu Koshimizu

Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits

scientific article published on January 2008

Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits

scientific article

Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons

scientific article published in June 2003

BIT/SHPS-1 promotes antiapoptotic effect of BDNF on low potassium-induced cell death of cultured cerebellar granule neurons

scientific article published on 08 May 2011

Biogenesis and transport of secretory granules to release site in neuroendocrine cells.

scientific article published on 08 July 2008

Brain-derived neurotrophic factor regulates cholesterol metabolism for synapse development

scientific article

Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons.

scientific article

Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase-2

scientific article published on 24 November 2018

Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice

scientific article

Corticotropin-releasing hormone-binding protein is upregulated by brain-derived neurotrophic factor and is secreted in an activity-dependent manner in rat cerebral cortical neurons

scientific article

Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia.

scientific article

Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons.

scientific article published on 26 February 2010

Distinct usages of phospholipase C gamma and Shc in intracellular signaling stimulated by neurotrophins.

scientific article published in November 2002

ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response

scientific article

Functional interaction between BDNF and mGluR II in vitro: BDNF down-regulated mGluR II gene expression and an mGluR II agonist enhanced BDNF-induced BDNF gene expression in rat cerebral cortical neurons

scientific article published on 21 January 2017

Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population

scientific article published on 31 January 2019

M4 muscarinic receptor knockout mice display abnormal social behavior and decreased prepulse inhibition.

scientific article

Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival.

scientific article published on 13 August 2009

Neuronal roles of the integrin-associated protein (IAP/CD47) in developing cortical neurons.

scientific article

Neuroprotective protein and carboxypeptidase E.

scientific article published on 23 January 2009

Reprint of: Chromogranin A: a new proposal for trafficking, processing and induction of granule biogenesis

scientific article

Roles of amino acid residues near the chromophore of photoactive yellow protein.

scientific article published in April 2001

Serpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells

scientific journal article

Serpinins: Role in Granule Biogenesis, Inhibition of Cell Death and Cardiac Function ⬇️

scientific article published on January 1, 2012

Shp-2 positively regulates brain-derived neurotrophic factor-promoted survival of cultured ventral mesencephalic dopaminergic neurons through a brain immunoglobulin-like molecule with tyrosine-based activation motifs/Shp substrate-1.

scientific article

The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropes

scientific journal article

Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism.

scientific article published on 15 March 2017

Vexin is upregulated in cerebral cortical neurons by brain-derived neurotrophic factor

scientific article published on 19 June 2020

List of works by Hisatsugu Koshimizu

Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits

Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits

Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons

BIT/SHPS-1 promotes antiapoptotic effect of BDNF on low potassium-induced cell death of cultured cerebellar granule neurons

Biogenesis and transport of secretory granules to release site in neuroendocrine cells.

Brain-derived neurotrophic factor regulates cholesterol metabolism for synapse development

Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons.

Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase-2

Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice

Corticotropin-releasing hormone-binding protein is upregulated by brain-derived neurotrophic factor and is secreted in an activity-dependent manner in rat cerebral cortical neurons

Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia.

Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons.

Distinct usages of phospholipase C gamma and Shc in intracellular signaling stimulated by neurotrophins.

ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response

Functional interaction between BDNF and mGluR II in vitro: BDNF down-regulated mGluR II gene expression and an mGluR II agonist enhanced BDNF-induced BDNF gene expression in rat cerebral cortical neurons

Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population

M4 muscarinic receptor knockout mice display abnormal social behavior and decreased prepulse inhibition.

Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival.

Neuronal roles of the integrin-associated protein (IAP/CD47) in developing cortical neurons.

Neuroprotective protein and carboxypeptidase E.

Reprint of: Chromogranin A: a new proposal for trafficking, processing and induction of granule biogenesis

Roles of amino acid residues near the chromophore of photoactive yellow protein.

Serpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells

Serpinins: Role in Granule Biogenesis, Inhibition of Cell Death and Cardiac Function ⬇️

Shp-2 positively regulates brain-derived neurotrophic factor-promoted survival of cultured ventral mesencephalic dopaminergic neurons through a brain immunoglobulin-like molecule with tyrosine-based activation motifs/Shp substrate-1.

The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropes

Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism.

Vexin is upregulated in cerebral cortical neurons by brain-derived neurotrophic factor