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List of works by Jonathan A Ledermann

2010 Gynecologic Cancer InterGroup (GCIG) Consensus Statement on Clinical Trials in Ovarian Cancer: Report From the Fourth Ovarian Cancer Consensus Conference ⬇️

scientific article published on May 1, 2011

A Phase 3 Trial of Bevacizumab in Ovarian Cancer ⬇️

scientific article published on December 29, 2011

A phase II study of weekly neoadjuvant chemotherapy followed by radical chemoradiation for locally advanced cervical cancer ⬇️

scientific article published on May 21, 2013

A randomised, placebo-controlled trial of weekly paclitaxel and saracatinib (AZD0530) in platinum-resistant ovarian, fallopian tube or primary peritoneal cancer†.

scientific article published on 28 July 2014

Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial

scientific article published on 12 February 2018

An Adaptive Study to Determine the Optimal Dose of the Tablet Formulation of the PARP Inhibitor Olaparib.

scientific article

An overview of early investigational therapies for chemoresistant ovarian cancer.

scientific article published on 24 July 2015

Benefits of Enhancing the Platinum-Free Interval in the Treatment of Relapsed Ovarian Cancer: More Than Just a Hypothesis? ⬇️

scientific article published on May 1, 2011

Biomarkers in the development of anti-angiogenic therapies for ovarian cancer ⬇️

scientific article published on December 29, 2011

Cediranib in patients with relapsed platinum-sensitive ovarian cancer (ICON6): a randomised, double-blind, placebo-controlled phase 3 trial.

scientific article

Clinical trials and decision-making strategies for optimal treatment of relapsed ovarian cancer ⬇️

scientific article published on September 1, 2011

Current academic clinical trials in ovarian cancer: Gynecologic Cancer Intergroup and US National Cancer Institute Clinical Trials Planning Meeting, May 2009

scientific article

Data set for reporting of ovary, fallopian tube and primary peritoneal carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR)

scientific article

ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma

scientific article published on 18 December 2020

ESMO-ESGO-ESTRO Consensus Conference on Endometrial Cancer: Diagnosis, Treatment and Follow-up

scientific article

Evidence for different mechanisms of 'unhooking' for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples.

scientific article

Exploratory outcome analyses according to stage and/or residual disease in the ICON7 trial of carboplatin and paclitaxel with or without bevacizumab for newly diagnosed ovarian cancer ⬇️

scientific article published on 16 November 2018

Family history and women with ovarian cancer: is it asked and does it matter?: An observational study

scientific article published on February 2012

First-line treatment of ovarian cancer: questions and controversies to address

scientific article published on 11 April 2018

Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the ovary

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for mucinous ovarian carcinoma

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian sex cord stromal tumors

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian tumors of low malignant potential (borderline ovarian tumors).

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for small cell carcinoma of the cervix.

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for squamous cell carcinoma of the ovary

scientific article

Gynecologic Cancer InterGroup (GCIG) consensus review for uterine and ovarian carcinosarcoma.

scientific article

High dose chemotherapy with peripheral blood stem cell transplantation (PBSCT) in ovarian cancer

scientific article

High-dose chemotherapy for solid tumors: results of the EBMT.

scientific article

Homologous recombination deficiency and ovarian cancer.

scientific article published on 8 April 2016

How should we manage patients with "platinum-sensitive" recurrent ovarian cancer?

scientific article

ICON 9-an international phase III randomized study to evaluate the efficacy of maintenance therapy with olaparib and cediranib or olaparib alone in patients with relapsed platinum-sensitive ovarian cancer following a response to platinum-based chemo

scientific article published on 23 October 2020

Inhibition of carboplatin-induced DNA interstrand cross-link repair by gemcitabine in patients receiving these drugs for platinum-resistant ovarian cancer.

scientific article

Intermediate clinical endpoints: a bridge between progression-free survival and overall survival in ovarian cancer trials

scientific article

Local Treatment of Unresectable Colorectal Liver Metastases: Results of a Randomized Phase II Trial

scientific article

Maintenance therapy in ovarian cancer.

scientific article published on September 2014

Management of platinum-sensitive recurrent ovarian cancer

scientific article

New clinical research strategies for rare gynecologic malignancies

scientific article published on February 2015

Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer

scientific article

Novel approaches to improve the treatment of rare gynecologic cancers: research opportunities and challenges

scientific article published on January 2014

OV21/PETROC: A randomized Gynecologic Cancer Intergroup phase II study of intraperitoneal versus intravenous chemotherapy following neoadjuvant chemotherapy and optimal debulking surgery in epithelial ovarian cancer

scientific article published on 23 November 2017

Olaparib as maintenance treatment for patients with platinum-sensitive relapsed ovarian cancer.

scientific article published on 22 May 2019

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial.

scientific article

Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serous ovarian cancer and a BRCA mutation: Overall survival adjusted for postprogression poly(adenosine diphosphate ribose) polymerase inhibitor therapy.

scientific article published on 08 April 2016

Olaparib treatment for BRCA-mutant ovarian cancer with leptomeningeal disease

scientific article published on 19 October 2016

Outcome of patients with advanced ovarian cancer who do not undergo debulking surgery: A single institution retrospective review.

scientific article published on 5 November 2016

Overall survival in patients with platinum-sensitive recurrent serous ovarian cancer receiving olaparib maintenance monotherapy: an updated analysis from a randomised, placebo-controlled, double-blind, phase 2 trial.

scientific article published on 08 September 2016

PARP inhibitors in ovarian cancer: Clinical evidence for informed treatment decisions

scientific article published on December 2015

Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer

scientific article published on 22 March 2016

Phase I and pharmacokinetic study of the polyamine synthesis inhibitor SAM486A in combination with 5-fluorouracil/leucovorin in metastatic colorectal cancer

scientific article published in March 2004

Pre-clinical assessment of autologous DC-based therapy in ovarian cancer patients with progressive disease

scientific article

Predicting response to bevacizumab in ovarian cancer: a panel of potential biomarkers informing treatment selection

scientific article

Primary chemotherapy: the future for the management of advanced ovarian cancer?

scientific article published on October 2010

Prolonged response of relapsed high grade serous ovarian carcinoma to the oral angiokinase inhibitor nintedanib in a patient with a germline BRCA1 mutation.

scientific article published on 17 October 2012

Role of molecular agents and targeted therapy in clinical trials for women with ovarian cancer.

scientific article published on May 2011

Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial ⬇️

scientific article

Targeted Therapies for Ovarian Cancer.

scientific article published on 8 December 2016

Targeted anti-vascular therapies for ovarian cancer: current evidence ⬇️

scientific article

Targeted trials in ovarian cancer

scientific article published on 29 June 2010

Toxicity and quality of life after adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): an open-label, multicentre, randomised, phase 3 trial

scientific article published on 7 July 2016

Update on rare epithelial ovarian cancers: based on the Rare Ovarian Tumors Young Investigator Conference.

scientific article

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