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List of works by Yoshitaka Fujihara

A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO.

scientific article

A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling

scientific article published on 05 July 2016

Activation of Myofibroblast TRPA1 by Steroids and Pirfenidone Ameliorates Fibrosis in Experimental Crohn's Disease.

scientific article published on 21 December 2017

An App knock-in mouse inducing the formation of a toxic conformer of Aβ as a model for evaluating only oligomer-induced cognitive decline in Alzheimer's disease

scientific article published on 01 June 2019

CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice

scientific article

CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice

scientific article published on 28 March 2020

CRISPR/Cas9-based genome editing in mice by single plasmid injection

scientific article published in January 2014

CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†

scientific article published on 01 August 2019

Calreticulin is required for development of the cumulus oocyte complex and female fertility

scientific article

Characterization of a BAC transgenic mouse expressing Krt19-driven iCre recombinase in its digestive organs

scientific article published on 08 August 2019

Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice

scientific article published on 08 October 2018

Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages.

scientific article published in January 2006

DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ

scientific article published on 04 March 2020

Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes

scientific article published on 28 July 2015

Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa

scientific article

Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models.

scientific article published on 22 January 2018

Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes.

scientific article

Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos.

scientific article published on 05 June 2014

GPI-AP release in cellular, developmental, and reproductive biology.

scientific article published on 22 November 2015

GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice

scientific journal article

Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA.

scientific article

Generation of precise point mutation mice by footprintless genome modification.

scientific article

Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice.

scientific article published on 29 June 2016

Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models.

scientific article published on 21 October 2017

Identification of an imprinted gene cluster in the X-inactivation center

scientific article

Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice

scientific article published on 27 August 2019

Induction of DNA methylation by artificial piRNA production in male germ cells.

scientific article published on 12 March 2015

JunB is essential for IL-23-dependent pathogenicity of Th17 cells

scientific article

Lentiviral Vector-Mediated Complementation Restored Fetal Viability but Not Placental Hyperplasia in Plac1-Deficient Mice.

scientific article published on 19 November 2015

Live imaging of X chromosome reactivation dynamics in early mouse development can discriminate naïve from primed pluripotent stem cells.

scientific article published on 28 July 2016

MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors.

scientific article published on 19 March 2018

Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa

scientific article published on May 23, 2012

NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility

scientific article published on 01 June 2020

Production of mouse pups from germline transmission-failed knockout chimeras.

scientific article published on 24 July 2012

Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a.

scientific article published on 22 January 2018

Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity†

scientific article published on 01 April 2019

Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive.

scientific article

Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse

scientific journal article

Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish

scientific article published on 07 April 2022

Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice

scientific article published on 11 May 2020

Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice

scientific article published on 15 April 2020

Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.

scientific article published on 15 July 2016

The Mg2+ transporter CNNM4 regulates sperm Ca2+ homeostasis and is essential for reproduction.

scientific article published on 22 March 2016

mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility

scientific article published on 26 September 2018