List of works - Ryo Yamada

A burden of rare variants in BMPR2 and KCNK3 contributes to a risk of familial pulmonary arterial hypertension.

scientific article

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

scientific article

A genome-wide association study of serum levels of prostate-specific antigen in the Japanese population

scientific article published on 11 June 2014

A high-throughput SNP typing system for genome-wide association studies

A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects

scientific article published on 27 August 2011

A multimedia intervention on cardiopulmonary resuscitation and advance directives.

scientific article

A nationwide study of SLE in Japanese identified subgroups of patients with clear signs patterns and associations between signs and age or sex.

scientific article published on 13 August 2014

A prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration

scientific article published on 23 August 2017

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

scientific article published on 09 May 2010

A twin study of rheumatoid arthritis in the Japanese population

scientific article published on 4 January 2016

Airflow limitation in smokers is associated with arterial stiffness: the Nagahama Study

scientific article published on 01 November 2013

An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes

scientific article published on 12 February 2013

An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka

scientific journal article

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

scientific article (publication date: December 2003)

An optimal dose-effect mode trend test for SNP genotype tables

scientific article published on 01 February 2009

Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis

scientific article

Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population

scientific article published on 18 April 2015

Application of permanents of square matrices for DNA identification in multiple-fatality cases

scientific article

Association between ZIC2, RASGRF1, and SHISA6 genes and high myopia in Japanese subjects

scientific article published on 13 November 2013

Association between antinuclear antibodies and the HLA class II locus and heterogeneous characteristics of staining patterns: the Nagahama study.

scientific article published in December 2014

Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy

scientific article published on February 2002

Association between the SERPING1 gene and age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese

scientific article

Association of 15q14 and 15q25 with high myopia in Japanese

scientific article published on 01 June 2011

Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy

scientific article

Association of genetic polymorphisms with interferon-induced haematologic adverse effects in chronic hepatitis C patients

scientific article

Association of longer QT interval with arterial waveform and lower pulse pressure amplification: the Nagahama Study

scientific article published on 18 April 2013

CCDC102B confers risk of low vision and blindness in high myopia.

scientific article

CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy.

scientific article published on 29 May 2018

Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization.

scientific article published on 26 June 2008

Citrullinated proteins in rheumatoid arthritis.

scientific article

Citrullination by peptidylarginine deiminase in rheumatoid arthritis.

scientific article published on June 2007

Combined association of clinical and lifestyle factors with non-restorative sleep: The Nagahama Study

scientific article

Comprehensive HLA Typing from a Current Allele Database Using Next-Generation Sequencing Data

scientific article published on 01 January 2018

Comprehensive assessment of the expression of the SWI/SNF complex defines two distinct prognostic subtypes of ovarian clear cell carcinoma.

scientific article published on 20 June 2016

Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis

scientific article published on August 2016

Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1

scientific article published on 01 December 2009

Cross-Sectional Epidemiological Analysis of the Nagahama Study for Correlates of Overactive Bladder: Genetic and Environmental Considerations.

scientific article published on 21 October 2017

Data-driven comparison of multiple high-dimensional single-cell expression profiles

scientific article published on 01 November 2021

Decomposition of a set of distributions in extended exponential family form for distinguishing multiple oligo-dimensional marker expression profiles of single-cell populations and visualizing their dynamics

scientific article published on 10 April 2020

Effects of smoking and shared epitope on the production of anti-citrullinated peptide antibody in a Japanese adult population

scientific article published on December 2014

Erratum: Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction

article

Estimation of P-value of MAX test with double triangle diagram for 2 x 3 SNP case-control tables

scientific article published on 01 September 2010

Ethnic differences in allele frequency of autoimmune-disease-associated SNPs.

scientific article published on 10 May 2005

Exome Sequencing Landscape Analysis in Ovarian Clear Cell Carcinoma Shed Light on Key Chromosomal Regions and Mutation Gene Networks.

scientific article published on 5 September 2017

FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.

scientific article published on November 2009

Gastroesophageal reflux disease symptoms and dietary behaviors are significant correlates of short sleep duration in the general population: the Nagahama Study

scientific article

Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population

scientific article published on 18 January 2019

Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese

scientific article

Genetic variants in pigment epithelium-derived factor influence response of polypoidal choroidal vasculopathy to photodynamic therapy

scientific article published on 24 March 2011

Genome-wide association analyses identify two susceptibility loci for pachychoroid disease central serous chorioretinopathy

scientific article published on 12 December 2019

Genome-wide association study of genetic factors related to confectionery intake: Potential roles of theADIPOQgene

scientific article published on 29 May 2013

Genome-wide single nucleotide polymorphism analyses of rheumatoid arthritis.

scientific article

HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis

scientific article published on 22 October 2009

Human genetic variation database, a reference database of genetic variations in the Japanese population

scientific article published on 25 February 2016

Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population

article

Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

scientific article

In silico study of medical decision-making for rare diseases: heterogeneity of decision-makers in a population improves overall benefit

scientific article published on 25 September 2018

Increased aortic wave reflection and smaller pulse pressure amplification in smokers and passive smokers confirmed by urinary cotinine levels: the Nagahama Study

scientific article published on 08 April 2013

Isotonic Regression Based-Method in Quantitative High-Throughput Screenings for Genotoxicity.

scientific article

Knee Pain and Low Back Pain Additively Disturb Sleep in the General Population: A Cross-Sectional Analysis of the Nagahama Study

scientific article

LAMPLINK: detection of statistically significant SNP combinations from GWAS data

scientific article

Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence variants

scientific article

Lessons from a genomewide association study of rheumatoid arthritis

scientific article published on 05 September 2007

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

scientific journal article

Mouth breathing, another risk factor for asthma: the Nagahama Study.

scientific article published on 17 March 2016

Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses

scientific article

Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury

scientific article published on 17 January 2019

No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese

scientific article published on 19 May 2006

PADI4 polymorphism predisposes male smokers to rheumatoid arthritis

scientific article published on 09 November 2010

PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population

scientific article published on 01 February 2013

POSH promotes cell survival in Drosophila and in human RASF cells.

scientific article published on 26 October 2010

Peptidylarginine deiminase type 4, anticitrullinated peptide antibodies, and rheumatoid arthritis.

scientific article

Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis

scientific article published on 29 May 2017

Prediction of taxane and platinum sensitivity in ovarian cancer based on gene expression profiles.

scientific article published in April 2016

Recent findings on genes associated with inflammatory disease.

scientific article

Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus

scientific article published on 01 March 2010

Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary Disease in A General Japanese Population: The Nagahama Study.

scientific article published on April 2016

Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.

scientific article published on 31 January 2018

Role of selected polymorphisms in determining muscle fiber composition in Japanese men and women.

scientific article published on 18 January 2018

SLC22A4 and RUNX1: identification of RA susceptible genes

scientific article

Significance ofC2/CFBVariants in Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in a Japanese Population

scientific article published on 16 February 2012

Significant association of periodontal disease with anti-citrullinated peptide antibody in a Japanese healthy population - The Nagahama study

scientific article published on 26 March 2015

Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye.

scientific article

The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.

scientific article published on 29 March 2010

The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population

scientific article published on 19 April 2011

Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels

scientific article published on 15 July 2015

Three-dimensional optical coherence tomography evaluation of vascular changes at arteriovenous crossings

scientific article published on 25 March 2014

Vascular endothelial growth factor gene polymorphisms and choroidal neovascularization in highly myopic eyes

scientific article published on 30 April 2012

[Rheumatoid arthritis nd citrullinated antigens]

scientific article published on 01 May 2005

[Studies on the genes related to rheumatoid arthritis and the application of the results to clinical medicine]

scientific article published on 01 September 2007

List of works by Ryo Yamada

A burden of rare variants in BMPR2 and KCNK3 contributes to a risk of familial pulmonary arterial hypertension.

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

A genome-wide association study of serum levels of prostate-specific antigen in the Japanese population

A high-throughput SNP typing system for genome-wide association studies

A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects

A multimedia intervention on cardiopulmonary resuscitation and advance directives.

A nationwide study of SLE in Japanese identified subgroups of patients with clear signs patterns and associations between signs and age or sex.

A prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

A twin study of rheumatoid arthritis in the Japanese population

Airflow limitation in smokers is associated with arterial stiffness: the Nagahama Study

An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes

An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

An optimal dose-effect mode trend test for SNP genotype tables

Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis

Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population

Application of permanents of square matrices for DNA identification in multiple-fatality cases

Association between ZIC2, RASGRF1, and SHISA6 genes and high myopia in Japanese subjects

Association between antinuclear antibodies and the HLA class II locus and heterogeneous characteristics of staining patterns: the Nagahama study.

Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy

Association between the SERPING1 gene and age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese

Association of 15q14 and 15q25 with high myopia in Japanese

Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy

Association of genetic polymorphisms with interferon-induced haematologic adverse effects in chronic hepatitis C patients

Association of longer QT interval with arterial waveform and lower pulse pressure amplification: the Nagahama Study

CCDC102B confers risk of low vision and blindness in high myopia.

CFH and VIPR2 as susceptibility loci in choroidal thickness and pachychoroid disease central serous chorioretinopathy.

Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization.

Citrullinated proteins in rheumatoid arthritis.

Citrullination by peptidylarginine deiminase in rheumatoid arthritis.

Combined association of clinical and lifestyle factors with non-restorative sleep: The Nagahama Study

Comprehensive HLA Typing from a Current Allele Database Using Next-Generation Sequencing Data

Comprehensive assessment of the expression of the SWI/SNF complex defines two distinct prognostic subtypes of ovarian clear cell carcinoma.

Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis

Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1

Cross-Sectional Epidemiological Analysis of the Nagahama Study for Correlates of Overactive Bladder: Genetic and Environmental Considerations.

Data-driven comparison of multiple high-dimensional single-cell expression profiles

Decomposition of a set of distributions in extended exponential family form for distinguishing multiple oligo-dimensional marker expression profiles of single-cell populations and visualizing their dynamics

Effects of smoking and shared epitope on the production of anti-citrullinated peptide antibody in a Japanese adult population

Erratum: Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction

Estimation of P-value of MAX test with double triangle diagram for 2 x 3 SNP case-control tables

Ethnic differences in allele frequency of autoimmune-disease-associated SNPs.

Exome Sequencing Landscape Analysis in Ovarian Clear Cell Carcinoma Shed Light on Key Chromosomal Regions and Mutation Gene Networks.

FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.

Gastroesophageal reflux disease symptoms and dietary behaviors are significant correlates of short sleep duration in the general population: the Nagahama Study

Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population

Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese

Genetic variants in pigment epithelium-derived factor influence response of polypoidal choroidal vasculopathy to photodynamic therapy

Genome-wide association analyses identify two susceptibility loci for pachychoroid disease central serous chorioretinopathy

Genome-wide association study of genetic factors related to confectionery intake: Potential roles of theADIPOQgene

Genome-wide single nucleotide polymorphism analyses of rheumatoid arthritis.

HLA-DRB1*0901 lowers anti-cyclic citrullinated peptide antibody levels in Japanese patients with rheumatoid arthritis

Human genetic variation database, a reference database of genetic variations in the Japanese population

Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population

Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

In silico study of medical decision-making for rare diseases: heterogeneity of decision-makers in a population improves overall benefit

Increased aortic wave reflection and smaller pulse pressure amplification in smokers and passive smokers confirmed by urinary cotinine levels: the Nagahama Study

Isotonic Regression Based-Method in Quantitative High-Throughput Screenings for Genotoxicity.

Knee Pain and Low Back Pain Additively Disturb Sleep in the General Population: A Cross-Sectional Analysis of the Nagahama Study

LAMPLINK: detection of statistically significant SNP combinations from GWAS data

Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence variants

Lessons from a genomewide association study of rheumatoid arthritis

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

Mouth breathing, another risk factor for asthma: the Nagahama Study.

Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses

Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury

No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese

PADI4 polymorphism predisposes male smokers to rheumatoid arthritis

PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population

POSH promotes cell survival in Drosophila and in human RASF cells.

Peptidylarginine deiminase type 4, anticitrullinated peptide antibodies, and rheumatoid arthritis.

Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis

Prediction of taxane and platinum sensitivity in ovarian cancer based on gene expression profiles.

Recent findings on genes associated with inflammatory disease.

Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus

Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary Disease in A General Japanese Population: The Nagahama Study.

Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers.

Role of selected polymorphisms in determining muscle fiber composition in Japanese men and women.